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7E0E

Crystal structure of mouse interferon alpha2 at 2.1 angstrom resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0002250biological_processadaptive immune response
A0002286biological_processT cell activation involved in immune response
A0002323biological_processnatural killer cell activation involved in immune response
A0005125molecular_functioncytokine activity
A0005126molecular_functioncytokine receptor binding
A0005132molecular_functiontype I interferon receptor binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006952biological_processdefense response
A0006959biological_processhumoral immune response
A0019221biological_processcytokine-mediated signaling pathway
A0030183biological_processB cell differentiation
A0033141biological_processpositive regulation of peptidyl-serine phosphorylation of STAT protein
A0042100biological_processB cell proliferation
A0043330biological_processresponse to exogenous dsRNA
A0051607biological_processdefense response to virus
Functional Information from PROSITE/UniProt
site_idPS00252
Number of Residues19
DetailsINTERFERON_A_B_D Interferon alpha, beta and delta family signature. YFhRItvYLrekkhspCAW
ChainResidueDetails
ATYR123-TRP141

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305
ChainResidueDetails
AASN78

223532

PDB entries from 2024-08-07

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