7DW7
Crystal Structure of N1051A mutant of Formylglycinamidine Synthetase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004642 | molecular_function | phosphoribosylformylglycinamidine synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0006541 | biological_process | glutamine metabolic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00419 |
| Chain | Residue | Details |
| A | CYS1135 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00419 |
| Chain | Residue | Details |
| A | HIS1260 | |
| A | GLU1262 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00419 |
| Chain | Residue | Details |
| A | GLY307 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | THR386 | |
| A | ALA678 | |
| A | SER886 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00419, ECO:0000269|PubMed:15301531, ECO:0000269|PubMed:22683785, ECO:0000269|PubMed:24223728 |
| Chain | Residue | Details |
| A | ASP679 | |
| A | GLU718 | |
| A | ASN722 | |
| A | ASP884 |
