7DVQ

Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0005515	molecular_function	protein binding
0	0005681	cellular_component	spliceosomal complex
0	0005737	cellular_component	cytoplasm
0	0006397	biological_process	mRNA processing
0	0008017	molecular_function	microtubule binding
0	0008380	biological_process	RNA splicing
0	0014069	cellular_component	postsynaptic density
0	0030165	molecular_function	PDZ domain binding
0	0030425	cellular_component	dendrite
0	0031122	biological_process	cytoplasmic microtubule organization
0	0035372	biological_process	protein localization to microtubule
0	0042995	cellular_component	cell projection
0	0043025	cellular_component	neuronal cell body
0	0043197	cellular_component	dendritic spine
0	0043198	cellular_component	dendritic shaft
0	0044877	molecular_function	protein-containing complex binding
0	0045184	biological_process	establishment of protein localization
0	0045202	cellular_component	synapse
0	0097110	molecular_function	scaffold protein binding
0	0098978	cellular_component	glutamatergic synapse
0	0099092	cellular_component	postsynaptic density, intracellular component
0	0099151	biological_process	regulation of postsynaptic density assembly
0	1902897	biological_process	regulation of postsynaptic density protein 95 clustering
1	0000245	biological_process	spliceosomal complex assembly
1	0000375	biological_process	RNA splicing, via transesterification reactions
1	0000398	biological_process	mRNA splicing, via spliceosome
1	0003723	molecular_function	RNA binding
1	0003729	molecular_function	mRNA binding
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005654	cellular_component	nucleoplasm
1	0005681	cellular_component	spliceosomal complex
1	0005684	cellular_component	U2-type spliceosomal complex
1	0005686	cellular_component	U2 snRNP
1	0005689	cellular_component	U12-type spliceosomal complex
1	0005730	cellular_component	nucleolus
1	0006338	biological_process	chromatin remodeling
1	0006397	biological_process	mRNA processing
1	0008380	biological_process	RNA splicing
1	0016607	cellular_component	nuclear speck
1	0034693	cellular_component	U11/U12 snRNP
1	0045943	biological_process	positive regulation of transcription by RNA polymerase I
1	0045944	biological_process	positive regulation of transcription by RNA polymerase II
1	0045945	biological_process	positive regulation of transcription by RNA polymerase III
1	0071004	cellular_component	U2-type prespliceosome
1	0071005	cellular_component	U2-type precatalytic spliceosome
1	0071013	cellular_component	catalytic step 2 spliceosome
1	0110016	cellular_component	B-WICH complex
1	1903241	biological_process	U2-type prespliceosome assembly
1	1990935	molecular_function	splicing factor binding
2	0000398	biological_process	mRNA splicing, via spliceosome
2	0003723	molecular_function	RNA binding
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005654	cellular_component	nucleoplasm
2	0005681	cellular_component	spliceosomal complex
2	0005684	cellular_component	U2-type spliceosomal complex
2	0005686	cellular_component	U2 snRNP
2	0005689	cellular_component	U12-type spliceosomal complex
2	0006397	biological_process	mRNA processing
2	0008380	biological_process	RNA splicing
2	0016607	cellular_component	nuclear speck
2	0071005	cellular_component	U2-type precatalytic spliceosome
2	0071011	cellular_component	precatalytic spliceosome
2	0071013	cellular_component	catalytic step 2 spliceosome
2	1903241	biological_process	U2-type prespliceosome assembly
3	0000124	cellular_component	SAGA complex
3	0000375	biological_process	RNA splicing, via transesterification reactions
3	0000398	biological_process	mRNA splicing, via spliceosome
3	0003676	molecular_function	nucleic acid binding
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005654	cellular_component	nucleoplasm
3	0005681	cellular_component	spliceosomal complex
3	0005684	cellular_component	U2-type spliceosomal complex
3	0005686	cellular_component	U2 snRNP
3	0005689	cellular_component	U12-type spliceosomal complex
3	0005730	cellular_component	nucleolus
3	0006282	biological_process	regulation of DNA repair
3	0006397	biological_process	mRNA processing
3	0008380	biological_process	RNA splicing
3	0030620	molecular_function	U2 snRNA binding
3	0042177	biological_process	negative regulation of protein catabolic process
3	0043484	biological_process	regulation of RNA splicing
3	0044877	molecular_function	protein-containing complex binding
3	0045893	biological_process	positive regulation of DNA-templated transcription
3	0071005	cellular_component	U2-type precatalytic spliceosome
3	0071013	cellular_component	catalytic step 2 spliceosome
3	1903241	biological_process	U2-type prespliceosome assembly
4	0000375	biological_process	RNA splicing, via transesterification reactions
4	0000398	biological_process	mRNA splicing, via spliceosome
4	0003676	molecular_function	nucleic acid binding
4	0003723	molecular_function	RNA binding
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005654	cellular_component	nucleoplasm
4	0005681	cellular_component	spliceosomal complex
4	0005684	cellular_component	U2-type spliceosomal complex
4	0005686	cellular_component	U2 snRNP
4	0005689	cellular_component	U12-type spliceosomal complex
4	0006397	biological_process	mRNA processing
4	0008380	biological_process	RNA splicing
4	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
4	0071005	cellular_component	U2-type precatalytic spliceosome
4	1903241	biological_process	U2-type prespliceosome assembly
4	1990935	molecular_function	splicing factor binding
5	0000398	biological_process	mRNA splicing, via spliceosome
5	0001825	biological_process	blastocyst formation
5	0003676	molecular_function	nucleic acid binding
5	0003723	molecular_function	RNA binding
5	0003729	molecular_function	mRNA binding
5	0005515	molecular_function	protein binding
5	0005634	cellular_component	nucleus
5	0005654	cellular_component	nucleoplasm
5	0005681	cellular_component	spliceosomal complex
5	0005684	cellular_component	U2-type spliceosomal complex
5	0005686	cellular_component	U2 snRNP
5	0005689	cellular_component	U12-type spliceosomal complex
5	0006397	biological_process	mRNA processing
5	0008380	biological_process	RNA splicing
5	0071011	cellular_component	precatalytic spliceosome
5	0071013	cellular_component	catalytic step 2 spliceosome
5	1903241	biological_process	U2-type prespliceosome assembly
6	0000398	biological_process	mRNA splicing, via spliceosome
6	0003677	molecular_function	DNA binding
6	0003723	molecular_function	RNA binding
6	0005515	molecular_function	protein binding
6	0005634	cellular_component	nucleus
6	0005654	cellular_component	nucleoplasm
6	0005681	cellular_component	spliceosomal complex
6	0005684	cellular_component	U2-type spliceosomal complex
6	0005686	cellular_component	U2 snRNP
6	0005689	cellular_component	U12-type spliceosomal complex
6	0006397	biological_process	mRNA processing
6	0008270	molecular_function	zinc ion binding
6	0008380	biological_process	RNA splicing
6	0016363	cellular_component	nuclear matrix
6	0016607	cellular_component	nuclear speck
6	0045893	biological_process	positive regulation of DNA-templated transcription
6	0046872	molecular_function	metal ion binding
6	0048863	biological_process	stem cell differentiation
6	0071005	cellular_component	U2-type precatalytic spliceosome
6	0071011	cellular_component	precatalytic spliceosome
6	1903241	biological_process	U2-type prespliceosome assembly
7	0000124	cellular_component	SAGA complex
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0003723	molecular_function	RNA binding
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005681	cellular_component	spliceosomal complex
7	0005684	cellular_component	U2-type spliceosomal complex
7	0005686	cellular_component	U2 snRNP
7	0005689	cellular_component	U12-type spliceosomal complex
7	0006282	biological_process	regulation of DNA repair
7	0006397	biological_process	mRNA processing
7	0008380	biological_process	RNA splicing
7	0043484	biological_process	regulation of RNA splicing
7	0045893	biological_process	positive regulation of DNA-templated transcription
7	0071005	cellular_component	U2-type precatalytic spliceosome
7	0071011	cellular_component	precatalytic spliceosome
7	1903241	biological_process	U2-type prespliceosome assembly
7	1990935	molecular_function	splicing factor binding
8	0000375	biological_process	RNA splicing, via transesterification reactions
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003677	molecular_function	DNA binding
8	0003723	molecular_function	RNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005681	cellular_component	spliceosomal complex
8	0005829	cellular_component	cytosol
8	0006397	biological_process	mRNA processing
8	0008380	biological_process	RNA splicing
8	0016363	cellular_component	nuclear matrix
8	0016607	cellular_component	nuclear speck
8	0048024	biological_process	regulation of mRNA splicing, via spliceosome
8	0071013	cellular_component	catalytic step 2 spliceosome
9	0000209	biological_process	protein polyubiquitination
9	0000413	biological_process	protein peptidyl-prolyl isomerization
9	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
9	0004842	molecular_function	ubiquitin-protein transferase activity
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005681	cellular_component	spliceosomal complex
9	0005737	cellular_component	cytoplasm
9	0005796	cellular_component	Golgi lumen
9	0005886	cellular_component	plasma membrane
9	0006397	biological_process	mRNA processing
9	0006457	biological_process	protein folding
9	0008380	biological_process	RNA splicing
9	0016018	molecular_function	cyclosporin A binding
9	0016567	biological_process	protein ubiquitination
9	0016740	molecular_function	transferase activity
9	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
9	0061630	molecular_function	ubiquitin protein ligase activity
9	0071013	cellular_component	catalytic step 2 spliceosome
9	0072659	biological_process	protein localization to plasma membrane
a	0000243	cellular_component	commitment complex
a	0000387	biological_process	spliceosomal snRNP assembly
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0005683	cellular_component	U7 snRNP
a	0005684	cellular_component	U2-type spliceosomal complex
a	0005685	cellular_component	U1 snRNP
a	0005686	cellular_component	U2 snRNP
a	0005687	cellular_component	U4 snRNP
a	0005689	cellular_component	U12-type spliceosomal complex
a	0005697	cellular_component	telomerase holoenzyme complex
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006396	biological_process	RNA processing
a	0006397	biological_process	mRNA processing
a	0006479	biological_process	protein methylation
a	0008380	biological_process	RNA splicing
a	0016604	cellular_component	nuclear body
a	0019899	molecular_function	enzyme binding
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0034709	cellular_component	methylosome
a	0034715	cellular_component	pICln-Sm protein complex
a	0034719	cellular_component	SMN-Sm protein complex
a	0036261	biological_process	7-methylguanosine cap hypermethylation
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0070034	molecular_function	telomerase RNA binding
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071011	cellular_component	precatalytic spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0071208	molecular_function	histone pre-mRNA DCP binding
a	0071209	molecular_function	U7 snRNA binding
a	0097526	cellular_component	spliceosomal tri-snRNP complex
a	1903241	biological_process	U2-type prespliceosome assembly
a	1990446	molecular_function	U1 snRNP binding
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005682	cellular_component	U5 snRNP
b	0005683	cellular_component	U7 snRNP
b	0005684	cellular_component	U2-type spliceosomal complex
b	0005685	cellular_component	U1 snRNP
b	0005686	cellular_component	U2 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005689	cellular_component	U12-type spliceosomal complex
b	0005697	cellular_component	telomerase holoenzyme complex
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0006479	biological_process	protein methylation
b	0008380	biological_process	RNA splicing
b	0030532	cellular_component	small nuclear ribonucleoprotein complex
b	0034709	cellular_component	methylosome
b	0034719	cellular_component	SMN-Sm protein complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0043229	cellular_component	intracellular organelle
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0070034	molecular_function	telomerase RNA binding
b	0070990	molecular_function	snRNP binding
b	0071004	cellular_component	U2-type prespliceosome
b	0071005	cellular_component	U2-type precatalytic spliceosome
b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
b	0071208	molecular_function	histone pre-mRNA DCP binding
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990446	molecular_function	U1 snRNP binding
b	1990447	molecular_function	U2 snRNP binding
c	0000243	cellular_component	commitment complex
c	0000245	biological_process	spliceosomal complex assembly
c	0000387	biological_process	spliceosomal snRNP assembly
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005681	cellular_component	spliceosomal complex
c	0005682	cellular_component	U5 snRNP
c	0005684	cellular_component	U2-type spliceosomal complex
c	0005685	cellular_component	U1 snRNP
c	0005686	cellular_component	U2 snRNP
c	0005687	cellular_component	U4 snRNP
c	0005689	cellular_component	U12-type spliceosomal complex
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0006396	biological_process	RNA processing
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0030532	cellular_component	small nuclear ribonucleoprotein complex
c	0034709	cellular_component	methylosome
c	0034715	cellular_component	pICln-Sm protein complex
c	0034719	cellular_component	SMN-Sm protein complex
c	0036261	biological_process	7-methylguanosine cap hypermethylation
c	0043229	cellular_component	intracellular organelle
c	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
c	0071005	cellular_component	U2-type precatalytic spliceosome
c	0071007	cellular_component	U2-type catalytic step 2 spliceosome
c	0071011	cellular_component	precatalytic spliceosome
c	0071013	cellular_component	catalytic step 2 spliceosome
c	0097526	cellular_component	spliceosomal tri-snRNP complex
c	1903241	biological_process	U2-type prespliceosome assembly
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0015030	cellular_component	Cajal body
C	0016020	cellular_component	membrane
C	0016607	cellular_component	nuclear speck
C	0030623	molecular_function	U5 snRNA binding
C	0042220	biological_process	response to cocaine
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071466	biological_process	cellular response to xenobiotic stimulus
d	0000245	biological_process	spliceosomal complex assembly
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005684	cellular_component	U2-type spliceosomal complex
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005689	cellular_component	U12-type spliceosomal complex
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006397	biological_process	mRNA processing
d	0008380	biological_process	RNA splicing
d	0030532	cellular_component	small nuclear ribonucleoprotein complex
d	0034709	cellular_component	methylosome
d	0034715	cellular_component	pICln-Sm protein complex
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0070062	cellular_component	extracellular exosome
d	0071005	cellular_component	U2-type precatalytic spliceosome
d	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	1903241	biological_process	U2-type prespliceosome assembly
D	0000354	biological_process	cis assembly of pre-catalytic spliceosome
D	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0001649	biological_process	osteoblast differentiation
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
D	0003724	molecular_function	RNA helicase activity
D	0004386	molecular_function	helicase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0042802	molecular_function	identical protein binding
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0071005	cellular_component	U2-type precatalytic spliceosome
D	0071006	cellular_component	U2-type catalytic step 1 spliceosome
D	0071013	cellular_component	catalytic step 2 spliceosome
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005683	cellular_component	U7 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005697	cellular_component	telomerase holoenzyme complex
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0043229	cellular_component	intracellular organelle
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	1903241	biological_process	U2-type prespliceosome assembly
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
E	0005829	cellular_component	cytosol
E	0006396	biological_process	RNA processing
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0016607	cellular_component	nuclear speck
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0071007	cellular_component	U2-type catalytic step 2 spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005683	cellular_component	U7 snRNP
f	0005684	cellular_component	U2-type spliceosomal complex
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005689	cellular_component	U12-type spliceosomal complex
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0006397	biological_process	mRNA processing
f	0008380	biological_process	RNA splicing
f	0030532	cellular_component	small nuclear ribonucleoprotein complex
f	0034709	cellular_component	methylosome
f	0034715	cellular_component	pICln-Sm protein complex
f	0034719	cellular_component	SMN-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071005	cellular_component	U2-type precatalytic spliceosome
f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0120114	cellular_component	Sm-like protein family complex
f	1903241	biological_process	U2-type prespliceosome assembly
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005683	cellular_component	U7 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0043186	cellular_component	P granule
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071004	cellular_component	U2-type prespliceosome
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
h	0000243	cellular_component	commitment complex
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005683	cellular_component	U7 snRNP
h	0005684	cellular_component	U2-type spliceosomal complex
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005689	cellular_component	U12-type spliceosomal complex
h	0005697	cellular_component	telomerase holoenzyme complex
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006396	biological_process	RNA processing
h	0006397	biological_process	mRNA processing
h	0006479	biological_process	protein methylation
h	0008380	biological_process	RNA splicing
h	0016604	cellular_component	nuclear body
h	0019899	molecular_function	enzyme binding
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034709	cellular_component	methylosome
h	0034715	cellular_component	pICln-Sm protein complex
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0070034	molecular_function	telomerase RNA binding
h	0071005	cellular_component	U2-type precatalytic spliceosome
h	0071007	cellular_component	U2-type catalytic step 2 spliceosome
h	0071011	cellular_component	precatalytic spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0071208	molecular_function	histone pre-mRNA DCP binding
h	0071209	molecular_function	U7 snRNA binding
h	0097526	cellular_component	spliceosomal tri-snRNP complex
h	1903241	biological_process	U2-type prespliceosome assembly
h	1990446	molecular_function	U1 snRNP binding
i	0000387	biological_process	spliceosomal snRNP assembly
i	0000398	biological_process	mRNA splicing, via spliceosome
i	0003723	molecular_function	RNA binding
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005681	cellular_component	spliceosomal complex
i	0005682	cellular_component	U5 snRNP
i	0005683	cellular_component	U7 snRNP
i	0005684	cellular_component	U2-type spliceosomal complex
i	0005685	cellular_component	U1 snRNP
i	0005686	cellular_component	U2 snRNP
i	0005687	cellular_component	U4 snRNP
i	0005689	cellular_component	U12-type spliceosomal complex
i	0005697	cellular_component	telomerase holoenzyme complex
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006397	biological_process	mRNA processing
i	0006479	biological_process	protein methylation
i	0008380	biological_process	RNA splicing
i	0030532	cellular_component	small nuclear ribonucleoprotein complex
i	0034709	cellular_component	methylosome
i	0034719	cellular_component	SMN-Sm protein complex
i	0036261	biological_process	7-methylguanosine cap hypermethylation
i	0043229	cellular_component	intracellular organelle
i	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
i	0070034	molecular_function	telomerase RNA binding
i	0070990	molecular_function	snRNP binding
i	0071004	cellular_component	U2-type prespliceosome
i	0071005	cellular_component	U2-type precatalytic spliceosome
i	0071007	cellular_component	U2-type catalytic step 2 spliceosome
i	0071013	cellular_component	catalytic step 2 spliceosome
i	0071204	cellular_component	histone pre-mRNA 3'end processing complex
i	0071208	molecular_function	histone pre-mRNA DCP binding
i	1903241	biological_process	U2-type prespliceosome assembly
i	1990446	molecular_function	U1 snRNP binding
i	1990447	molecular_function	U2 snRNP binding
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005654	cellular_component	nucleoplasm
I	0005681	cellular_component	spliceosomal complex
I	0006397	biological_process	mRNA processing
I	0008380	biological_process	RNA splicing
j	0000243	cellular_component	commitment complex
j	0000245	biological_process	spliceosomal complex assembly
j	0000387	biological_process	spliceosomal snRNP assembly
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003723	molecular_function	RNA binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005681	cellular_component	spliceosomal complex
j	0005682	cellular_component	U5 snRNP
j	0005684	cellular_component	U2-type spliceosomal complex
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005689	cellular_component	U12-type spliceosomal complex
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0006396	biological_process	RNA processing
j	0006397	biological_process	mRNA processing
j	0008380	biological_process	RNA splicing
j	0030532	cellular_component	small nuclear ribonucleoprotein complex
j	0034709	cellular_component	methylosome
j	0034715	cellular_component	pICln-Sm protein complex
j	0034719	cellular_component	SMN-Sm protein complex
j	0036261	biological_process	7-methylguanosine cap hypermethylation
j	0043229	cellular_component	intracellular organelle
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0071005	cellular_component	U2-type precatalytic spliceosome
j	0071007	cellular_component	U2-type catalytic step 2 spliceosome
j	0071011	cellular_component	precatalytic spliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	0097526	cellular_component	spliceosomal tri-snRNP complex
j	1903241	biological_process	U2-type prespliceosome assembly
J	0000245	biological_process	spliceosomal complex assembly
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0000974	cellular_component	Prp19 complex
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005681	cellular_component	spliceosomal complex
J	0006396	biological_process	RNA processing
J	0006397	biological_process	mRNA processing
J	0008380	biological_process	RNA splicing
J	0016607	cellular_component	nuclear speck
J	0071007	cellular_component	U2-type catalytic step 2 spliceosome
J	0071013	cellular_component	catalytic step 2 spliceosome
J	0071014	cellular_component	post-mRNA release spliceosomal complex
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005684	cellular_component	U2-type spliceosomal complex
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005689	cellular_component	U12-type spliceosomal complex
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0030532	cellular_component	small nuclear ribonucleoprotein complex
k	0034709	cellular_component	methylosome
k	0034715	cellular_component	pICln-Sm protein complex
k	0034719	cellular_component	SMN-Sm protein complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0070062	cellular_component	extracellular exosome
k	0071005	cellular_component	U2-type precatalytic spliceosome
k	0071007	cellular_component	U2-type catalytic step 2 spliceosome
k	0071011	cellular_component	precatalytic spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	1903241	biological_process	U2-type prespliceosome assembly
K	0005515	molecular_function	protein binding
K	0005681	cellular_component	spliceosomal complex
K	0006397	biological_process	mRNA processing
K	0008380	biological_process	RNA splicing
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005683	cellular_component	U7 snRNP
l	0005684	cellular_component	U2-type spliceosomal complex
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005689	cellular_component	U12-type spliceosomal complex
l	0005697	cellular_component	telomerase holoenzyme complex
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034709	cellular_component	methylosome
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0043229	cellular_component	intracellular organelle
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0071005	cellular_component	U2-type precatalytic spliceosome
l	0071007	cellular_component	U2-type catalytic step 2 spliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	1903241	biological_process	U2-type prespliceosome assembly
L	0000077	biological_process	DNA damage checkpoint signaling
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000974	cellular_component	Prp19 complex
L	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
L	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
L	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
L	0003677	molecular_function	DNA binding
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005662	cellular_component	DNA replication factor A complex
L	0005681	cellular_component	spliceosomal complex
L	0005737	cellular_component	cytoplasm
L	0006281	biological_process	DNA repair
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0016020	cellular_component	membrane
L	0016607	cellular_component	nuclear speck
L	0042802	molecular_function	identical protein binding
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0071007	cellular_component	U2-type catalytic step 2 spliceosome
L	0071013	cellular_component	catalytic step 2 spliceosome
L	0071987	molecular_function	WD40-repeat domain binding
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005683	cellular_component	U7 snRNP
m	0005684	cellular_component	U2-type spliceosomal complex
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005689	cellular_component	U12-type spliceosomal complex
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0034709	cellular_component	methylosome
m	0034715	cellular_component	pICln-Sm protein complex
m	0034719	cellular_component	SMN-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0071005	cellular_component	U2-type precatalytic spliceosome
m	0071007	cellular_component	U2-type catalytic step 2 spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	0120114	cellular_component	Sm-like protein family complex
m	1903241	biological_process	U2-type prespliceosome assembly
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005681	cellular_component	spliceosomal complex
M	0005684	cellular_component	U2-type spliceosomal complex
M	0006281	biological_process	DNA repair
M	0006397	biological_process	mRNA processing
M	0008380	biological_process	RNA splicing
M	0016567	biological_process	protein ubiquitination
M	0016607	cellular_component	nuclear speck
M	0016740	molecular_function	transferase activity
M	0034247	biological_process	snoRNA splicing
M	0046872	molecular_function	metal ion binding
M	0061630	molecular_function	ubiquitin protein ligase activity
M	0070100	biological_process	negative regulation of chemokine-mediated signaling pathway
M	0071005	cellular_component	U2-type precatalytic spliceosome
n	0000245	biological_process	spliceosomal complex assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005683	cellular_component	U7 snRNP
n	0005684	cellular_component	U2-type spliceosomal complex
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005689	cellular_component	U12-type spliceosomal complex
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006397	biological_process	mRNA processing
n	0008380	biological_process	RNA splicing
n	0030532	cellular_component	small nuclear ribonucleoprotein complex
n	0034709	cellular_component	methylosome
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0043186	cellular_component	P granule
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0071004	cellular_component	U2-type prespliceosome
n	0071005	cellular_component	U2-type precatalytic spliceosome
n	0071007	cellular_component	U2-type catalytic step 2 spliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0000974	cellular_component	Prp19 complex
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005681	cellular_component	spliceosomal complex
P	0005739	cellular_component	mitochondrion
P	0006397	biological_process	mRNA processing
P	0008380	biological_process	RNA splicing
P	0016607	cellular_component	nuclear speck
P	0045292	biological_process	mRNA cis splicing, via spliceosome
P	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P	0071013	cellular_component	catalytic step 2 spliceosome
R	0000122	biological_process	negative regulation of transcription by RNA polymerase II
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0003713	molecular_function	transcription coactivator activity
R	0003714	molecular_function	transcription corepressor activity
R	0003723	molecular_function	RNA binding
R	0005112	molecular_function	Notch binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005681	cellular_component	spliceosomal complex
R	0006357	biological_process	regulation of transcription by RNA polymerase II
R	0006397	biological_process	mRNA processing
R	0008024	cellular_component	cyclin/CDK positive transcription elongation factor complex
R	0008380	biological_process	RNA splicing
R	0016363	cellular_component	nuclear matrix
R	0016604	cellular_component	nuclear body
R	0016607	cellular_component	nuclear speck
R	0016922	molecular_function	nuclear receptor binding
R	0019899	molecular_function	enzyme binding
R	0030511	biological_process	positive regulation of transforming growth factor beta receptor signaling pathway
R	0042771	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
R	0042809	molecular_function	nuclear vitamin D receptor binding
R	0042974	molecular_function	nuclear retinoic acid receptor binding
R	0043923	biological_process	positive regulation by host of viral transcription
R	0045892	biological_process	negative regulation of DNA-templated transcription
R	0045944	biological_process	positive regulation of transcription by RNA polymerase II
R	0046332	molecular_function	SMAD binding
R	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
R	0048384	biological_process	retinoic acid receptor signaling pathway
R	0048385	biological_process	regulation of retinoic acid receptor signaling pathway
R	0050681	molecular_function	nuclear androgen receptor binding
R	0050769	biological_process	positive regulation of neurogenesis
R	0070562	biological_process	regulation of vitamin D receptor signaling pathway
R	0070564	biological_process	positive regulation of vitamin D receptor signaling pathway
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071013	cellular_component	catalytic step 2 spliceosome
R	0071300	biological_process	cellular response to retinoic acid
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0000974	cellular_component	Prp19 complex
T	0001650	cellular_component	fibrillar center
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005662	cellular_component	DNA replication factor A complex
T	0005681	cellular_component	spliceosomal complex
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016607	cellular_component	nuclear speck
T	0031965	cellular_component	nuclear membrane
T	0034504	biological_process	protein localization to nucleus
T	0071007	cellular_component	U2-type catalytic step 2 spliceosome
T	0071013	cellular_component	catalytic step 2 spliceosome
T	1900087	biological_process	positive regulation of G1/S transition of mitotic cell cycle
U	0000398	biological_process	mRNA splicing, via spliceosome
U	0003723	molecular_function	RNA binding
U	0003729	molecular_function	mRNA binding
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005681	cellular_component	spliceosomal complex
U	0006397	biological_process	mRNA processing
U	0008380	biological_process	RNA splicing
U	0015030	cellular_component	Cajal body
U	0016607	cellular_component	nuclear speck
U	0070742	molecular_function	C2H2 zinc finger domain binding
U	0071005	cellular_component	U2-type precatalytic spliceosome
U	0071007	cellular_component	U2-type catalytic step 2 spliceosome
U	0071013	cellular_component	catalytic step 2 spliceosome
v	0000380	biological_process	alternative mRNA splicing, via spliceosome
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005681	cellular_component	spliceosomal complex
v	0006397	biological_process	mRNA processing
v	0008380	biological_process	RNA splicing
v	0016607	cellular_component	nuclear speck
v	0019899	molecular_function	enzyme binding
v	0046872	molecular_function	metal ion binding
V	0000398	biological_process	mRNA splicing, via spliceosome
V	0003723	molecular_function	RNA binding
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005681	cellular_component	spliceosomal complex
V	0005829	cellular_component	cytosol
V	0006397	biological_process	mRNA processing
V	0008380	biological_process	RNA splicing
V	0016607	cellular_component	nuclear speck
V	0048024	biological_process	regulation of mRNA splicing, via spliceosome
V	0071005	cellular_component	U2-type precatalytic spliceosome
V	0071006	cellular_component	U2-type catalytic step 1 spliceosome
V	0071007	cellular_component	U2-type catalytic step 2 spliceosome
V	0071013	cellular_component	catalytic step 2 spliceosome
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0003676	molecular_function	nucleic acid binding
x	0003723	molecular_function	RNA binding
x	0003724	molecular_function	RNA helicase activity
x	0004386	molecular_function	helicase activity
x	0005515	molecular_function	protein binding
x	0005524	molecular_function	ATP binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0005681	cellular_component	spliceosomal complex
x	0005737	cellular_component	cytoplasm
x	0006397	biological_process	mRNA processing
x	0008380	biological_process	RNA splicing
x	0016787	molecular_function	hydrolase activity
x	0016887	molecular_function	ATP hydrolysis activity
x	0038187	molecular_function	pattern recognition receptor activity
x	0043130	molecular_function	ubiquitin binding
x	0045087	biological_process	innate immune response
x	0060090	molecular_function	molecular adaptor activity
x	0071005	cellular_component	U2-type precatalytic spliceosome
x	0140374	biological_process	antiviral innate immune response
X	0000398	biological_process	mRNA splicing, via spliceosome
X	0003723	molecular_function	RNA binding
X	0003729	molecular_function	mRNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005681	cellular_component	spliceosomal complex
X	0005686	cellular_component	U2 snRNP
X	0005829	cellular_component	cytosol
X	0006397	biological_process	mRNA processing
X	0008380	biological_process	RNA splicing
X	0031047	biological_process	regulatory ncRNA-mediated gene silencing
X	0035196	biological_process	miRNA processing
X	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
X	0071005	cellular_component	U2-type precatalytic spliceosome
X	0140416	molecular_function	transcription regulator inhibitor activity
X	1903241	biological_process	U2-type prespliceosome assembly
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0003676	molecular_function	nucleic acid binding
y	0003723	molecular_function	RNA binding
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005681	cellular_component	spliceosomal complex
y	0006397	biological_process	mRNA processing
y	0008380	biological_process	RNA splicing
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0003676	molecular_function	nucleic acid binding
Y	0003723	molecular_function	RNA binding
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005681	cellular_component	spliceosomal complex
Y	0005686	cellular_component	U2 snRNP
Y	0005730	cellular_component	nucleolus
Y	0005783	cellular_component	endoplasmic reticulum
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0031965	cellular_component	nuclear membrane
Y	0071005	cellular_component	U2-type precatalytic spliceosome
Y	0071011	cellular_component	precatalytic spliceosome
Y	1903241	biological_process	U2-type prespliceosome assembly
z	0000398	biological_process	mRNA splicing, via spliceosome
z	0000413	biological_process	protein peptidyl-prolyl isomerization
z	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0006457	biological_process	protein folding
z	0016018	molecular_function	cyclosporin A binding
z	0071005	cellular_component	U2-type precatalytic spliceosome
z	0071013	cellular_component	catalytic step 2 spliceosome
Z	0000398	biological_process	mRNA splicing, via spliceosome
Z	0003723	molecular_function	RNA binding
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005681	cellular_component	spliceosomal complex
Z	0005684	cellular_component	U2-type spliceosomal complex
Z	0005686	cellular_component	U2 snRNP
Z	0006397	biological_process	mRNA processing
Z	0008380	biological_process	RNA splicing
Z	0070274	cellular_component	RES complex
Z	0071005	cellular_component	U2-type precatalytic spliceosome
Z	1903241	biological_process	U2-type prespliceosome assembly

Functional Information from PROSITE/UniProt

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YdnTiFHRVVpgFIvQGG

Chain	Residue	Details
z	TYR49-GLY66
9	TYR316-GLY333

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
3	PHE287-HIS293

---

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CrHyFCesCA

Chain	Residue	Details
M	CYS277-ALA286

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAgfDrLILLWNV

Chain	Residue	Details
E	LEU81-VAL95
E	LEU124-SER138
E	VAL167-ILE181
E	ILE208-LEU222
E	ILE300-THR314
T	LEU303-VAL317
T	ILE345-LEU359

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SvVMVDEAHE

Chain	Residue	Details
x	SER515-GLU524

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N-acetylserine => ECO:0000269|Ref.6, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712

Chain	Residue	Details
d	SER2
6	CYS72
6	CYS75
6	CYS85
k	SER2
j	LYS86
i	ARG112
Z	SER281
Z	SER391
Z	SER407
Z	SER567
6	CYS61

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
d	SER9
k	SER9
T	SER391
R	SER446
R	SER479
R	SER481

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
d	THR12
k	THR12
1	GLU1205

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
d	LYS6
1	THR235
d	LYS8
k	LYS6
k	LYS8

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
D	THR389
U	SER1460
U	SER1462
U	SER1482
U	SER1483
U	SER1501
U	SER1621
U	SER1893
U	SER2343
U	SER2394
U	SER2453
D	THR1428
U	SER454
U	SER484
U	SER486
U	SER875
U	SER1336
U	SER1368
U	SER1421

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:F1LNJ2

Chain	Residue	Details
D	TYR709
R	LYS416
R	LYS441
R	LYS452
U	THR1892
Y	LYS243
R	LYS141
R	LYS158
R	LYS258
R	LYS286
R	LYS339
R	LYS344

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
D	LYS971
8	SER797
8	SER802

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q6P4T2

Chain	Residue	Details
D	THR1765
U	SER1179
U	SER2581

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
D	SER2002
U	SER1083
U	SER1152

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
D	THR2131
U	SER857
U	SER952
U	SER1318
U	SER1401
U	SER2100

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
D	SER2133
D	SER2135
Z	SER248

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
D	LYS46
U	SER353
2	LYS280
2	LYS492
2	LYS543
2	LYS770
2	LYS790
2	LYS843
2	LYS857

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:15144186, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER402
U	SER358
U	SER846
U	SER1214

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:15144186, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	THR406
U	THR1106
U	THR2381

---

site_id	SWS_FT_FI15
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
8	SER414
8	SER420
8	SER583
8	SER707
8	SER795

---

site_id	SWS_FT_FI16
Number of Residues	6
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
8	THR416
8	THR555
8	THR572
8	THR574
8	THR581
8	THR793

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER429
8	SER431
8	SER605
8	SER607

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
8	SER436
8	SER777

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER450
U	SER935
U	SER1311
1	THR303
1	THR313

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER452

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER463
8	SER465

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:20068231

Chain	Residue	Details
8	SER478
U	SER1124
U	SER2702

---

site_id	SWS_FT_FI23
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER524
U	SER2121
U	SER2675
U	SER2677
8	SER526
8	SER528
8	SER530
8	SER532
8	SER773
8	SER901
U	SER1541
U	SER1876

---

site_id	SWS_FT_FI24
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER549
U	SER704
U	SER706
U	SER992
U	SER1198
U	SER1227
U	SER1254
U	SER1257
U	SER1258
U	SER2018
U	SER2030
8	SER551
U	SER2042
U	SER2310
U	SER2368
U	SER2376
U	SER2740
8	SER705
U	SER508
U	SER510
U	SER534
U	SER536
U	SER543
U	SER702

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER560
8	SER562

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	TYR596
U	SER2123
U	SER2398
U	SER2407
U	SER2692

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER597
U	SER1522
U	SER1970

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	THR614
U	SER1423
U	SER1616
U	SER1620
U	SER1024
U	SER1042
U	SER1266
U	SER1270
U	SER1271
U	SER1348
U	SER1383
U	SER1384

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER616

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
8	SER626
8	SER628

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
8	SER636

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER638
1	THR436

---

site_id	SWS_FT_FI33
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER694
U	SER1582
U	SER1598
U	SER1600
U	SER1601
U	SER1658
U	SER1727
U	SER1729
U	SER1731
U	SER1732
U	SER1818
8	SER715
U	SER1822
U	SER1884
U	SER2090
U	SER2415
U	SER2429
8	SER748
U	SER1517
U	SER1519
U	SER1521
U	SER1577
U	SER1579
U	SER1581

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q52KI8

Chain	Residue	Details
8	SER695

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER696

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER713
U	SER1946
U	SER1958
U	SER2118
U	SER968
U	SER970
U	SER972
U	SER1032
U	SER1451
U	SER1691
U	SER1693
U	SER1923

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	THR718
U	SER1975
U	SER1984
U	SER1987
U	SER1996
U	SER1999
U	SER2008
U	SER2011
U	SER2664
U	SER2706
U	SER1497
U	SER1502
U	SER1762
U	SER1764
U	SER1890
U	SER1916
U	SER1919
U	SER1972

---

site_id	SWS_FT_FI38
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER738
U	SER1415
U	SER1925
U	SER1948
U	SER1960

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER740
U	THR1043
U	THR1931
U	THR1954
U	THR1966
U	THR1978
U	THR2092

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER752

---

site_id	SWS_FT_FI41
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER754
8	SER756

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER769

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER775

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q52KI8

Chain	Residue	Details
8	THR778
U	SER2690

---

site_id	SWS_FT_FI45
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER781
U	SER1444
U	SER1542
U	SER1552
U	SER1694
U	SER1878
U	SER2412

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	SER791
U	SER1073

---

site_id	SWS_FT_FI47
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
8	THR872
U	SER1101

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
8	SER874

---

site_id	SWS_FT_FI49
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
8	LYS127
U	SER1404
8	LYS447
8	LYS459
8	LYS472
8	LYS869

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
8	LYS231
U	SER1857
U	SER2335

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
8	LYS249

---

site_id	SWS_FT_FI52
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR1208
U	THR1880

---

site_id	SWS_FT_FI53
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
U	SER1219

---

site_id	SWS_FT_FI54
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
U	SER1320
U	SER1387

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
U	SER1326

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
U	SER1329

---

site_id	SWS_FT_FI57
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	SER1382

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	SER1403

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR1413

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR1434

---

site_id	SWS_FT_FI61
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
U	THR1453
U	THR1472
U	THR1511
U	THR1698
U	THR2144

---

site_id	SWS_FT_FI62
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	SER1458
U	SER1648
U	SER2020
U	SER2032
U	SER2067

---

site_id	SWS_FT_FI63
Number of Residues	9
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	SER1463
U	SER1499
U	SER1854
U	SER2044
U	SER2046
U	SER2071
U	SER2426
U	SER2684
U	SER2688

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR1492

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR1531

---

site_id	SWS_FT_FI66
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
U	THR1927
U	THR1950
U	THR1962

---

site_id	SWS_FT_FI67
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR2022
U	THR2034

---

site_id	SWS_FT_FI68
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR2069

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	SER2102

---

site_id	SWS_FT_FI70
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR2104

---

site_id	SWS_FT_FI71
Number of Residues	7
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
U	ARG2194
U	ARG2207
U	ARG2231
U	ARG2246
U	ARG2274
U	ARG2288
U	ARG2342

---

site_id	SWS_FT_FI72
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
U	SER2272

---

site_id	SWS_FT_FI73
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR2289

---

site_id	SWS_FT_FI74
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243

Chain	Residue	Details
U	THR2291

---

site_id	SWS_FT_FI75
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
U	THR2302

---

site_id	SWS_FT_FI76
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR2316

---

site_id	SWS_FT_FI77
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR2329
U	THR2409

---

site_id	SWS_FT_FI78
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
U	SER2382

---

site_id	SWS_FT_FI79
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine; alternate => ECO:0007744|PubMed:24129315

Chain	Residue	Details
U	ARG2384

---

site_id	SWS_FT_FI80
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	SER2449

---

site_id	SWS_FT_FI81
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
U	THR2583

---

site_id	SWS_FT_FI82
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	THR2599
U	THR2738

---

site_id	SWS_FT_FI83
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
U	SER2694

---

site_id	SWS_FT_FI84
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
U	LYS108
U	LYS130
U	LYS2587

---