7DSA
Crystal structure of actin capping protein in complex with V-1 (space group P62)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008290 | cellular_component | F-actin capping protein complex |
| A | 0030018 | cellular_component | Z disc |
| A | 0030036 | biological_process | actin cytoskeleton organization |
| A | 0030863 | cellular_component | cortical cytoskeleton |
| A | 0034329 | biological_process | cell junction assembly |
| A | 0051015 | molecular_function | actin filament binding |
| A | 0051016 | biological_process | barbed-end actin filament capping |
| A | 0051693 | biological_process | actin filament capping |
| A | 0071203 | cellular_component | WASH complex |
| B | 0003779 | molecular_function | actin binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008290 | cellular_component | F-actin capping protein complex |
| B | 0030036 | biological_process | actin cytoskeleton organization |
| B | 0051016 | biological_process | barbed-end actin filament capping |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006417 | biological_process | regulation of translation |
| C | 0008290 | cellular_component | F-actin capping protein complex |
| C | 0008361 | biological_process | regulation of cell size |
| C | 0010557 | biological_process | positive regulation of macromolecule biosynthetic process |
| C | 0010613 | biological_process | positive regulation of cardiac muscle hypertrophy |
| C | 0016202 | biological_process | regulation of striated muscle tissue development |
| C | 0030182 | biological_process | neuron differentiation |
| C | 0030307 | biological_process | positive regulation of cell growth |
| C | 0048471 | cellular_component | perinuclear region of cytoplasm |
| C | 0051092 | biological_process | positive regulation of NF-kappaB transcription factor activity |
| C | 0051247 | biological_process | positive regulation of protein metabolic process |
| C | 2000812 | biological_process | regulation of barbed-end actin filament capping |
Functional Information from PROSITE/UniProt
| site_id | PS00231 |
| Number of Residues | 6 |
| Details | F_ACTIN_CAPPING_BETA F-actin capping protein beta subunit signature. CDYNRD |
| Chain | Residue | Details |
| B | CYS62-ASP67 |
| site_id | PS00748 |
| Number of Residues | 9 |
| Details | F_ACTIN_CAPPING_A_1 F-actin capping protein alpha subunit signature 1. VHYYEDGNV |
| Chain | Residue | Details |
| A | VAL196-VAL204 |
| site_id | PS00749 |
| Number of Residues | 11 |
| Details | F_ACTIN_CAPPING_A_2 F-actin capping protein alpha subunit signature 2. KaLRRqLPVTR |
| Chain | Residue | Details |
| A | LYS256-ARG266 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Repeat: {"description":"ANK 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Repeat: {"description":"ANK 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 32 |
| Details | Repeat: {"description":"ANK 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylcysteine","evidences":[{"source":"UniProtKB","id":"P62774","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
