7DL9
Crystal structure of nucleoside transporter NupG
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005337 | molecular_function | nucleoside transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015212 | molecular_function | cytidine transmembrane transporter activity |
| A | 0015213 | molecular_function | uridine transmembrane transporter activity |
| A | 0015214 | molecular_function | pyrimidine nucleoside transmembrane transporter activity |
| A | 0015293 | molecular_function | symporter activity |
| A | 0015506 | molecular_function | nucleoside:proton symporter activity |
| A | 0015858 | biological_process | nucleoside transport |
| A | 0015860 | biological_process | purine nucleoside transmembrane transport |
| A | 0015861 | biological_process | cytidine transport |
| A | 0015862 | biological_process | uridine transmembrane transport |
| A | 0015864 | biological_process | pyrimidine nucleoside transport |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0032238 | biological_process | adenosine transport |
| A | 1901642 | biological_process | nucleoside transmembrane transport |
| B | 0005337 | molecular_function | nucleoside transmembrane transporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0015212 | molecular_function | cytidine transmembrane transporter activity |
| B | 0015213 | molecular_function | uridine transmembrane transporter activity |
| B | 0015214 | molecular_function | pyrimidine nucleoside transmembrane transporter activity |
| B | 0015293 | molecular_function | symporter activity |
| B | 0015506 | molecular_function | nucleoside:proton symporter activity |
| B | 0015858 | biological_process | nucleoside transport |
| B | 0015860 | biological_process | purine nucleoside transmembrane transport |
| B | 0015861 | biological_process | cytidine transport |
| B | 0015862 | biological_process | uridine transmembrane transport |
| B | 0015864 | biological_process | pyrimidine nucleoside transport |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0032238 | biological_process | adenosine transport |
| B | 1901642 | biological_process | nucleoside transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue OLC A 501 |
| Chain | Residue |
| A | PHE84 |
| A | ALA166 |
| B | PHE175 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue OLC A 502 |
| Chain | Residue |
| B | LEU5 |
| B | LYS8 |
| B | TRP138 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 184 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:33640454, ECO:0007744|PDB:7DL9 |
| Chain | Residue | Details |
| A | MET1-LYS4 | |
| B | LEU179-ARG209 | |
| B | LEU269-ILE280 | |
| B | ILE327-GLN346 | |
| A | GLY59-SER67 | |
| A | ASN114-ILE135 | |
| A | LEU179-ARG209 | |
| A | LEU269-ILE280 | |
| A | ILE327-GLN346 | |
| B | MET1-LYS4 | |
| B | GLY59-SER67 | |
| B | ASN114-ILE135 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 510 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:33640454, ECO:0007744|PDB:7DL9 |
| Chain | Residue | Details |
| A | LEU5-MET29 | |
| A | PHE306-ASN326 | |
| A | GLY347-VAL369 | |
| A | TRP380-LYS403 | |
| B | LEU5-MET29 | |
| B | GLY37-LEU58 | |
| B | ALA68-GLN88 | |
| B | PRO92-ILE113 | |
| B | ARG136-GLU156 | |
| B | HIS159-THR178 | |
| B | MET210-HIS236 | |
| A | GLY37-LEU58 | |
| B | PHE248-ILE268 | |
| B | LYS281-TYR300 | |
| B | PHE306-ASN326 | |
| B | GLY347-VAL369 | |
| B | TRP380-LYS403 | |
| A | ALA68-GLN88 | |
| A | PRO92-ILE113 | |
| A | ARG136-GLU156 | |
| A | HIS159-THR178 | |
| A | MET210-HIS236 | |
| A | PHE248-ILE268 | |
| A | LYS281-TYR300 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 64 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:33640454, ECO:0007744|PDB:7DL9 |
| Chain | Residue | Details |
| A | PHE30-ASP36 | |
| B | SER237-SER247 | |
| B | GLY301-PRO305 | |
| B | GLU370-ASP379 | |
| A | VAL89-THR91 | |
| A | LEU157-SER158 | |
| A | SER237-SER247 | |
| A | GLY301-PRO305 | |
| A | GLU370-ASP379 | |
| B | PHE30-ASP36 | |
| B | VAL89-THR91 | |
| B | LEU157-SER158 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:33640454, ECO:0007744|PDB:7DL9 |
| Chain | Residue | Details |
| A | TYR404-HIS418 | |
| B | TYR404-HIS418 |
