7DKF

Activity optimized supercomplex state4

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
12	0003954	molecular_function	NADH dehydrogenase activity
12	0005739	cellular_component	mitochondrion
12	0005743	cellular_component	mitochondrial inner membrane
12	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
12	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
12	0009060	biological_process	aerobic respiration
12	0016020	cellular_component	membrane
12	0032981	biological_process	mitochondrial respiratory chain complex I assembly
12	0045271	cellular_component	respiratory chain complex I
12	0070469	cellular_component	respirasome
12	1902600	biological_process	proton transmembrane transport
22	0005739	cellular_component	mitochondrion
22	0005743	cellular_component	mitochondrial inner membrane
22	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
22	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
22	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
22	0032981	biological_process	mitochondrial respiratory chain complex I assembly
22	0045271	cellular_component	respiratory chain complex I
22	0070469	cellular_component	respirasome
22	1902600	biological_process	proton transmembrane transport
32	0005739	cellular_component	mitochondrion
32	0005743	cellular_component	mitochondrial inner membrane
32	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
32	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
32	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
32	0045271	cellular_component	respiratory chain complex I
32	0070469	cellular_component	respirasome
32	1902600	biological_process	proton transmembrane transport
42	0003954	molecular_function	NADH dehydrogenase activity
42	0005739	cellular_component	mitochondrion
42	0005743	cellular_component	mitochondrial inner membrane
42	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
42	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
42	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
42	0009060	biological_process	aerobic respiration
42	0015990	biological_process	electron transport coupled proton transport
42	0032981	biological_process	mitochondrial respiratory chain complex I assembly
42	0042773	biological_process	ATP synthesis coupled electron transport
42	0045271	cellular_component	respiratory chain complex I
42	0048039	molecular_function	ubiquinone binding
42	0070469	cellular_component	respirasome
52	0005739	cellular_component	mitochondrion
52	0005743	cellular_component	mitochondrial inner membrane
52	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
52	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
52	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
52	0042773	biological_process	ATP synthesis coupled electron transport
52	0045271	cellular_component	respiratory chain complex I
52	0070469	cellular_component	respirasome
52	1902600	biological_process	proton transmembrane transport
62	0003954	molecular_function	NADH dehydrogenase activity
62	0005739	cellular_component	mitochondrion
62	0005743	cellular_component	mitochondrial inner membrane
62	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
62	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
62	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
62	0015990	biological_process	electron transport coupled proton transport
62	0032981	biological_process	mitochondrial respiratory chain complex I assembly
62	0042773	biological_process	ATP synthesis coupled electron transport
62	0045271	cellular_component	respiratory chain complex I
62	0070469	cellular_component	respirasome
72	0005739	cellular_component	mitochondrion
72	0005743	cellular_component	mitochondrial inner membrane
72	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
72	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
72	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
72	0032981	biological_process	mitochondrial respiratory chain complex I assembly
72	0070469	cellular_component	respirasome
72	1902600	biological_process	proton transmembrane transport
82	0005739	cellular_component	mitochondrion
82	0005743	cellular_component	mitochondrial inner membrane
82	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
82	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
82	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
82	0010181	molecular_function	FMN binding
82	0016491	molecular_function	oxidoreductase activity
82	0045271	cellular_component	respiratory chain complex I
82	0046872	molecular_function	metal ion binding
82	0051287	molecular_function	NAD binding
82	0051539	molecular_function	4 iron, 4 sulfur cluster binding
82	0070469	cellular_component	respirasome
82	1902600	biological_process	proton transmembrane transport
92	0016491	molecular_function	oxidoreductase activity
A1	0005739	cellular_component	mitochondrion
A1	0005743	cellular_component	mitochondrial inner membrane
A1	0046872	molecular_function	metal ion binding
A1	0070469	cellular_component	respirasome
a2	0005739	cellular_component	mitochondrion
a2	0005743	cellular_component	mitochondrial inner membrane
a2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
a2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
a2	0045271	cellular_component	respiratory chain complex I
a2	0070469	cellular_component	respirasome
A2	0005739	cellular_component	mitochondrion
A2	0005743	cellular_component	mitochondrial inner membrane
A2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
A2	0005758	cellular_component	mitochondrial intermembrane space
A2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A2	0008637	biological_process	apoptotic mitochondrial changes
A2	0009055	molecular_function	electron transfer activity
A2	0016020	cellular_component	membrane
A2	0016491	molecular_function	oxidoreductase activity
A2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
A2	0042773	biological_process	ATP synthesis coupled electron transport
A2	0045271	cellular_component	respiratory chain complex I
A2	0045333	biological_process	cellular respiration
A2	0046034	biological_process	ATP metabolic process
A2	0046872	molecular_function	metal ion binding
A2	0051536	molecular_function	iron-sulfur cluster binding
A2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A2	0051881	biological_process	regulation of mitochondrial membrane potential
A2	0070469	cellular_component	respirasome
A2	0072593	biological_process	reactive oxygen species metabolic process
A2	1902600	biological_process	proton transmembrane transport
A3	0004129	molecular_function	cytochrome-c oxidase activity
A3	0005739	cellular_component	mitochondrion
A3	0005743	cellular_component	mitochondrial inner membrane
A3	0005751	cellular_component	mitochondrial respiratory chain complex IV
A3	0006119	biological_process	oxidative phosphorylation
A3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A3	0009060	biological_process	aerobic respiration
A3	0015990	biological_process	electron transport coupled proton transport
A3	0016020	cellular_component	membrane
A3	0020037	molecular_function	heme binding
A3	0045277	cellular_component	respiratory chain complex IV
A3	0046872	molecular_function	metal ion binding
A3	0070469	cellular_component	respirasome
B1	0004222	molecular_function	metalloendopeptidase activity
B1	0005739	cellular_component	mitochondrion
B1	0005743	cellular_component	mitochondrial inner membrane
B1	0006508	biological_process	proteolysis
B1	0046872	molecular_function	metal ion binding
B1	0070469	cellular_component	respirasome
B2	0003954	molecular_function	NADH dehydrogenase activity
B2	0005654	cellular_component	nucleoplasm
B2	0005739	cellular_component	mitochondrion
B2	0005743	cellular_component	mitochondrial inner membrane
B2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
B2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B2	0006979	biological_process	response to oxidative stress
B2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B2	0016491	molecular_function	oxidoreductase activity
B2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
B2	0019826	molecular_function	oxygen sensor activity
B2	0022008	biological_process	neurogenesis
B2	0031625	molecular_function	ubiquitin protein ligase binding
B2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B2	0042063	biological_process	gliogenesis
B2	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
B2	0045271	cellular_component	respiratory chain complex I
B2	0046872	molecular_function	metal ion binding
B2	0048038	molecular_function	quinone binding
B2	0051287	molecular_function	NAD binding
B2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B2	0061351	biological_process	neural precursor cell proliferation
B2	0070469	cellular_component	respirasome
B2	0071453	biological_process	cellular response to oxygen levels
B2	1902600	biological_process	proton transmembrane transport
B3	0004129	molecular_function	cytochrome-c oxidase activity
B3	0005507	molecular_function	copper ion binding
B3	0005739	cellular_component	mitochondrion
B3	0005743	cellular_component	mitochondrial inner membrane
B3	0016020	cellular_component	membrane
B3	0016491	molecular_function	oxidoreductase activity
B3	0022900	biological_process	electron transport chain
B3	0042773	biological_process	ATP synthesis coupled electron transport
B3	0045277	cellular_component	respiratory chain complex IV
B3	0046872	molecular_function	metal ion binding
B3	0070469	cellular_component	respirasome
B3	1902600	biological_process	proton transmembrane transport
C1	0005739	cellular_component	mitochondrion
C1	0005743	cellular_component	mitochondrial inner membrane
C1	0005750	cellular_component	mitochondrial respiratory chain complex III
C1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
C1	0009055	molecular_function	electron transfer activity
C1	0016020	cellular_component	membrane
C1	0016491	molecular_function	oxidoreductase activity
C1	0020037	molecular_function	heme binding
C1	0022904	biological_process	respiratory electron transport chain
C1	0031966	cellular_component	mitochondrial membrane
C1	0045275	cellular_component	respiratory chain complex III
C1	0046872	molecular_function	metal ion binding
C1	0048039	molecular_function	ubiquinone binding
C1	0070469	cellular_component	respirasome
C1	1902600	biological_process	proton transmembrane transport
c2	0005654	cellular_component	nucleoplasm
c2	0005739	cellular_component	mitochondrion
c2	0005743	cellular_component	mitochondrial inner membrane
c2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
c2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c2	0031966	cellular_component	mitochondrial membrane
c2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
c2	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
c2	0045271	cellular_component	respiratory chain complex I
c2	0070469	cellular_component	respirasome
C2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C3	0004129	molecular_function	cytochrome-c oxidase activity
C3	0005739	cellular_component	mitochondrion
C3	0005743	cellular_component	mitochondrial inner membrane
C3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
C3	0008535	biological_process	respiratory chain complex IV assembly
C3	0009055	molecular_function	electron transfer activity
C3	0016020	cellular_component	membrane
C3	0019646	biological_process	aerobic electron transport chain
C3	0022904	biological_process	respiratory electron transport chain
C3	0045277	cellular_component	respiratory chain complex IV
C3	1902600	biological_process	proton transmembrane transport
D1	0005739	cellular_component	mitochondrion
D1	0005743	cellular_component	mitochondrial inner membrane
D1	0005750	cellular_component	mitochondrial respiratory chain complex III
D1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
D1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
D1	0009055	molecular_function	electron transfer activity
D1	0020037	molecular_function	heme binding
D1	0046872	molecular_function	metal ion binding
D1	0070469	cellular_component	respirasome
D1	1902600	biological_process	proton transmembrane transport
d2	0005739	cellular_component	mitochondrion
d2	0005743	cellular_component	mitochondrial inner membrane
d2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
d2	0005758	cellular_component	mitochondrial intermembrane space
d2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
d2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
d2	0045271	cellular_component	respiratory chain complex I
d2	0070469	cellular_component	respirasome
d2	1902600	biological_process	proton transmembrane transport
D2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D2	0048038	molecular_function	quinone binding
D2	0051536	molecular_function	iron-sulfur cluster binding
D2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D3	0004129	molecular_function	cytochrome-c oxidase activity
D3	0005739	cellular_component	mitochondrion
D3	0005743	cellular_component	mitochondrial inner membrane
D3	0005751	cellular_component	mitochondrial respiratory chain complex IV
D3	0006119	biological_process	oxidative phosphorylation
D3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
D3	0045277	cellular_component	respiratory chain complex IV
D3	1902600	biological_process	proton transmembrane transport
E1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
E1	0016020	cellular_component	membrane
E1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
e2	0005739	cellular_component	mitochondrion
e2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
e2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
E2	0016020	cellular_component	membrane
E2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
E2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E3	0004129	molecular_function	cytochrome-c oxidase activity
E3	0005739	cellular_component	mitochondrion
E3	0005743	cellular_component	mitochondrial inner membrane
E3	0005751	cellular_component	mitochondrial respiratory chain complex IV
E3	0006119	biological_process	oxidative phosphorylation
E3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
E3	0045277	cellular_component	respiratory chain complex IV
E3	0046872	molecular_function	metal ion binding
E3	1902600	biological_process	proton transmembrane transport
F1	0005739	cellular_component	mitochondrion
F1	0005743	cellular_component	mitochondrial inner membrane
F1	0005750	cellular_component	mitochondrial respiratory chain complex III
F1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F1	0070469	cellular_component	respirasome
f2	0005739	cellular_component	mitochondrion
f2	0005743	cellular_component	mitochondrial inner membrane
f2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
f2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
f2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
f2	0045271	cellular_component	respiratory chain complex I
f2	0070469	cellular_component	respirasome
F2	0005739	cellular_component	mitochondrion
F2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
F3	0005739	cellular_component	mitochondrion
F3	0005740	cellular_component	mitochondrial envelope
F3	0005743	cellular_component	mitochondrial inner membrane
F3	0005751	cellular_component	mitochondrial respiratory chain complex IV
F3	0006119	biological_process	oxidative phosphorylation
F3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
F3	0045277	cellular_component	respiratory chain complex IV
F3	0046872	molecular_function	metal ion binding
G1	0005739	cellular_component	mitochondrion
G1	0005743	cellular_component	mitochondrial inner membrane
G1	0005750	cellular_component	mitochondrial respiratory chain complex III
G1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G1	0070469	cellular_component	respirasome
g2	0005739	cellular_component	mitochondrion
g2	0005743	cellular_component	mitochondrial inner membrane
g2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
g2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
g2	0045271	cellular_component	respiratory chain complex I
g2	0070469	cellular_component	respirasome
G2	0022900	biological_process	electron transport chain
G3	0005739	cellular_component	mitochondrion
G3	0005743	cellular_component	mitochondrial inner membrane
G3	0005751	cellular_component	mitochondrial respiratory chain complex IV
G3	0006119	biological_process	oxidative phosphorylation
G3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
G3	0016491	molecular_function	oxidoreductase activity
G3	0030234	molecular_function	enzyme regulator activity
G3	0045277	cellular_component	respiratory chain complex IV
H1	0005739	cellular_component	mitochondrion
H1	0005743	cellular_component	mitochondrial inner membrane
H1	0005750	cellular_component	mitochondrial respiratory chain complex III
H1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
H1	0070469	cellular_component	respirasome
H2	0005739	cellular_component	mitochondrion
H2	0005743	cellular_component	mitochondrial inner membrane
H2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
H2	0005758	cellular_component	mitochondrial intermembrane space
H2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
H2	0045271	cellular_component	respiratory chain complex I
H2	0070469	cellular_component	respirasome
H3	0005739	cellular_component	mitochondrion
H3	0005743	cellular_component	mitochondrial inner membrane
H3	0006119	biological_process	oxidative phosphorylation
H3	0045277	cellular_component	respiratory chain complex IV
I1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
i2	0005739	cellular_component	mitochondrion
i2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
I2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
I2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
I3	0005739	cellular_component	mitochondrion
I3	0005743	cellular_component	mitochondrial inner membrane
I3	0006119	biological_process	oxidative phosphorylation
I3	0045277	cellular_component	respiratory chain complex IV
J1	0005739	cellular_component	mitochondrion
J1	0005743	cellular_component	mitochondrial inner membrane
J1	0005750	cellular_component	mitochondrial respiratory chain complex III
J1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J1	0070469	cellular_component	respirasome
j2	0005739	cellular_component	mitochondrion
j2	0005743	cellular_component	mitochondrial inner membrane
j2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
j2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
j2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
j2	0045271	cellular_component	respiratory chain complex I
j2	0070469	cellular_component	respirasome
J2	0005739	cellular_component	mitochondrion
J2	0005743	cellular_component	mitochondrial inner membrane
J2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
J2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
J2	0045271	cellular_component	respiratory chain complex I
J2	0070469	cellular_component	respirasome
J3	0002082	biological_process	regulation of oxidative phosphorylation
J3	0005739	cellular_component	mitochondrion
J3	0005743	cellular_component	mitochondrial inner membrane
J3	0005746	cellular_component	mitochondrial respirasome
J3	0005751	cellular_component	mitochondrial respiratory chain complex IV
J3	0006119	biological_process	oxidative phosphorylation
J3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
J3	0016491	molecular_function	oxidoreductase activity
J3	0045277	cellular_component	respiratory chain complex IV
J3	0097250	biological_process	mitochondrial respirasome assembly
K1	0005739	cellular_component	mitochondrion
K1	0005743	cellular_component	mitochondrial inner membrane
K1	0005750	cellular_component	mitochondrial respiratory chain complex III
K1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
K1	0070469	cellular_component	respirasome
K2	0005739	cellular_component	mitochondrion
K2	0005743	cellular_component	mitochondrial inner membrane
K2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
K2	0031966	cellular_component	mitochondrial membrane
K2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
K2	0045271	cellular_component	respiratory chain complex I
K2	0070469	cellular_component	respirasome
K3	0005739	cellular_component	mitochondrion
K3	0005743	cellular_component	mitochondrial inner membrane
K3	0005746	cellular_component	mitochondrial respirasome
K3	0006119	biological_process	oxidative phosphorylation
K3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
K3	0007417	biological_process	central nervous system development
K3	0045277	cellular_component	respiratory chain complex IV
L2	0005739	cellular_component	mitochondrion
L2	0005743	cellular_component	mitochondrial inner membrane
L2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
L2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
L2	0045271	cellular_component	respiratory chain complex I
L2	0070469	cellular_component	respirasome
L3	0005739	cellular_component	mitochondrion
L3	0005743	cellular_component	mitochondrial inner membrane
L3	0005751	cellular_component	mitochondrial respiratory chain complex IV
L3	0006119	biological_process	oxidative phosphorylation
L3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
L3	0045277	cellular_component	respiratory chain complex IV
M1	0005739	cellular_component	mitochondrion
M1	0005743	cellular_component	mitochondrial inner membrane
M1	0046872	molecular_function	metal ion binding
M1	0070469	cellular_component	respirasome
M2	0006633	biological_process	fatty acid biosynthetic process
M3	0005739	cellular_component	mitochondrion
M3	0005743	cellular_component	mitochondrial inner membrane
M3	0005751	cellular_component	mitochondrial respiratory chain complex IV
M3	0006119	biological_process	oxidative phosphorylation
M3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
M3	0045277	cellular_component	respiratory chain complex IV
N1	0004222	molecular_function	metalloendopeptidase activity
N1	0005739	cellular_component	mitochondrion
N1	0005743	cellular_component	mitochondrial inner membrane
N1	0006508	biological_process	proteolysis
N1	0046872	molecular_function	metal ion binding
N1	0070469	cellular_component	respirasome
N2	0005739	cellular_component	mitochondrion
N2	0005743	cellular_component	mitochondrial inner membrane
N2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
N2	0022904	biological_process	respiratory electron transport chain
N2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
N2	0045271	cellular_component	respiratory chain complex I
N2	0070469	cellular_component	respirasome
O1	0005739	cellular_component	mitochondrion
O1	0005743	cellular_component	mitochondrial inner membrane
O1	0005750	cellular_component	mitochondrial respiratory chain complex III
O1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
O1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
O1	0009055	molecular_function	electron transfer activity
O1	0016020	cellular_component	membrane
O1	0016491	molecular_function	oxidoreductase activity
O1	0020037	molecular_function	heme binding
O1	0022904	biological_process	respiratory electron transport chain
O1	0031966	cellular_component	mitochondrial membrane
O1	0045275	cellular_component	respiratory chain complex III
O1	0046872	molecular_function	metal ion binding
O1	0048039	molecular_function	ubiquinone binding
O1	0070469	cellular_component	respirasome
O1	1902600	biological_process	proton transmembrane transport
O2	0005739	cellular_component	mitochondrion
O2	0005743	cellular_component	mitochondrial inner membrane
O2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
O2	0006979	biological_process	response to oxidative stress
O2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
O2	0045271	cellular_component	respiratory chain complex I
O2	0070469	cellular_component	respirasome
P1	0005739	cellular_component	mitochondrion
P1	0005743	cellular_component	mitochondrial inner membrane
P1	0005750	cellular_component	mitochondrial respiratory chain complex III
P1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
P1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
P1	0009055	molecular_function	electron transfer activity
P1	0020037	molecular_function	heme binding
P1	0046872	molecular_function	metal ion binding
P1	0070469	cellular_component	respirasome
P1	1902600	biological_process	proton transmembrane transport
P2	0005739	cellular_component	mitochondrion
P2	0005743	cellular_component	mitochondrial inner membrane
P2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
P2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
P2	0016491	molecular_function	oxidoreductase activity
P2	0042773	biological_process	ATP synthesis coupled electron transport
P2	0045271	cellular_component	respiratory chain complex I
P2	0070469	cellular_component	respirasome
Q1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
Q1	0016020	cellular_component	membrane
Q1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Q2	0005739	cellular_component	mitochondrion
Q2	0005743	cellular_component	mitochondrial inner membrane
Q2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
Q2	0005758	cellular_component	mitochondrial intermembrane space
Q2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
Q2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Q2	0045271	cellular_component	respiratory chain complex I
Q2	0070469	cellular_component	respirasome
R1	0005739	cellular_component	mitochondrion
R1	0005743	cellular_component	mitochondrial inner membrane
R1	0005750	cellular_component	mitochondrial respiratory chain complex III
R1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
R1	0070469	cellular_component	respirasome
R2	0005739	cellular_component	mitochondrion
R2	0005759	cellular_component	mitochondrial matrix
R2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
R2	0044877	molecular_function	protein-containing complex binding
R2	0045271	cellular_component	respiratory chain complex I
R2	0070469	cellular_component	respirasome
R2	1901006	biological_process	ubiquinone-6 biosynthetic process
S1	0005739	cellular_component	mitochondrion
S1	0005743	cellular_component	mitochondrial inner membrane
S1	0005750	cellular_component	mitochondrial respiratory chain complex III
S1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
S1	0070469	cellular_component	respirasome
S2	0005737	cellular_component	cytoplasm
S2	0005739	cellular_component	mitochondrion
S2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
S2	0005759	cellular_component	mitochondrial matrix
S2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S2	0045271	cellular_component	respiratory chain complex I
S2	0070469	cellular_component	respirasome
T1	0005739	cellular_component	mitochondrion
T1	0005743	cellular_component	mitochondrial inner membrane
T1	0005750	cellular_component	mitochondrial respiratory chain complex III
T1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
T1	0070469	cellular_component	respirasome
T2	0005739	cellular_component	mitochondrion
T2	0005743	cellular_component	mitochondrial inner membrane
T2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
T2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
T2	0045271	cellular_component	respiratory chain complex I
T2	0070469	cellular_component	respirasome
U1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
U2	0005739	cellular_component	mitochondrion
U2	0005743	cellular_component	mitochondrial inner membrane
U2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
U2	0006979	biological_process	response to oxidative stress
U2	0016020	cellular_component	membrane
U2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
U2	0045271	cellular_component	respiratory chain complex I
U2	0070469	cellular_component	respirasome
V1	0005739	cellular_component	mitochondrion
V1	0005743	cellular_component	mitochondrial inner membrane
V1	0005750	cellular_component	mitochondrial respiratory chain complex III
V1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
V1	0070469	cellular_component	respirasome
V2	0005634	cellular_component	nucleus
V2	0005654	cellular_component	nucleoplasm
V2	0005737	cellular_component	cytoplasm
V2	0005739	cellular_component	mitochondrion
V2	0005743	cellular_component	mitochondrial inner membrane
V2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
V2	0006915	biological_process	apoptotic process
V2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
V2	0045271	cellular_component	respiratory chain complex I
V2	0045892	biological_process	negative regulation of DNA-templated transcription
V2	0070469	cellular_component	respirasome
V2	1902600	biological_process	proton transmembrane transport
W1	0005739	cellular_component	mitochondrion
W1	0005743	cellular_component	mitochondrial inner membrane
W1	0005750	cellular_component	mitochondrial respiratory chain complex III
W1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
W1	0070469	cellular_component	respirasome
W2	0006633	biological_process	fatty acid biosynthetic process
X2	0005739	cellular_component	mitochondrion
X2	0005743	cellular_component	mitochondrial inner membrane
X2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
X2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
X2	0045271	cellular_component	respiratory chain complex I
X2	0070469	cellular_component	respirasome
Y2	0005743	cellular_component	mitochondrial inner membrane
Y2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
Z2	0005739	cellular_component	mitochondrion
Z2	0005743	cellular_component	mitochondrial inner membrane
Z2	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
Z2	0022900	biological_process	electron transport chain
Z2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Z2	0045271	cellular_component	respiratory chain complex I
Z2	0070469	cellular_component	respirasome

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
M2	ASP39-MET54

---

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
M2	ASP64-ILE76

---

site_id	PS00077
Number of Residues	56
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwa.HH

Chain	Residue	Details
A3	TRP236-HIS291

---

site_id	PS00078
Number of Residues	49
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. VlHswavpslglktdaipgrlnqttlmssrpglyygq......CseiCgsnHsfM

Chain	Residue	Details
B3	VAL159-MET207

---

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryensnnlGtSHLLRLAsSlTT

Chain	Residue	Details
B1	GLY54-THR77

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
E2	CYS113-PRO124
E2	CYS152-PRO163

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
B2	LEU116-LYS127

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL

Chain	Residue	Details
C2	GLU169-LEU190

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
A2	PRO61-CYS78

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
A2	CYS128-GLN140

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
A2	ARG175-PHE185

---

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
82	GLY200-SER215

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
82	GLU377-GLY388

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE

Chain	Residue	Details
12	GLY44-GLU59

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
12	PRO197-GLY210

---

site_id	PS00848
Number of Residues	23
Details	COX5B_1 Cytochrome c oxidase subunit Vb, zinc binding region signature. VIWfwlhkgeaqrCpsCGthYKL

Chain	Residue	Details
F3	VAL69-LEU91

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
92	ASP166-PRO184

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
D2	GLY172-PRO188

---

site_id	PS01329
Number of Residues	18
Details	COX6A Cytochrome c oxidase subunit VIa signature. IRtKpFsWGDGnHTfFhN

Chain	Residue	Details
G3	ILE55-ASN72

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P99028

Chain	Residue	Details
H1	LYS29
62	LEU310-CYS330
62	MET366-LEU386
62	LEU413-GLY433
62	LEU457-ILE477
62	MET482-LEU502
62	GLY582-PHE602
O1	TYR347-PRO367
H1	LYS72
T1	LYS29
T1	LYS72
A3	SER401-ASN406
A3	LYS479-LYS514
62	LEU213-LEU233
62	THR241-ILE261
62	ILE273-LEU293

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	TRANSMEM: Helical => ECO:0000269|PubMed:9651245

Chain	Residue	Details
G1	ARG39-GLU67
S1	ARG39-GLU67
F3	LYS90
R1	LYS18
R1	LYS82
R1	LYS95

---

site_id	SWS_FT_FI3
Number of Residues	26
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269|PubMed:9651245

Chain	Residue	Details
G1	LYS68-ARG81
S1	LYS68-ARG81
R1	LYS77
R1	LYS87

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q9CQ69

Chain	Residue	Details
G1	LYS32
Q1	SER163
S1	LYS32
E1	CYS158
E1	HIS161
E1	SER163
Q1	CYS139
Q1	HIS141
Q1	CYS158
Q1	HIS161

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P13073

Chain	Residue	Details
D3	LYS31
B3	CYS196
B3	GLU198
B3	CYS200
B3	HIS204
B3	MET207

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P10888

Chain	Residue	Details
D3	SER34
D3	SER36
A3	VAL287-ASP298

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P19783

Chain	Residue	Details
D3	LYS45

---

site_id	SWS_FT_FI8
Number of Residues	32
Details	TRANSMEM: Helical; Name=VI => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	GLY191-LEU223

---

site_id	SWS_FT_FI9
Number of Residues	23
Details	TRANSMEM: Helical; Name=VII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	PHE233-ILE256

---

site_id	SWS_FT_FI10
Number of Residues	16
Details	TRANSMEM: Helical; Name=VII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	TYR270-ILE286

---

site_id	SWS_FT_FI11
Number of Residues	28
Details	TRANSMEM: Helical; Name=VIII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	VAL299-LEU327

---

site_id	SWS_FT_FI12
Number of Residues	7
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	HIS328-SER335

---

site_id	SWS_FT_FI13
Number of Residues	21
Details	TRANSMEM: Helical; Name=IX => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	PRO336-VAL357

---

site_id	SWS_FT_FI14
Number of Residues	24
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	LEU358-THR370
A3	SER434-ALA446

---

site_id	SWS_FT_FI15
Number of Residues	29
Details	TRANSMEM: Helical; Name=X => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	TYR371-PHE400

---

site_id	SWS_FT_FI16
Number of Residues	26
Details	TRANSMEM: Helical; Name=XI => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	ASP407-LEU433

---

site_id	SWS_FT_FI17
Number of Residues	31
Details	TRANSMEM: Helical; Name=XII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	TYR447-SER478

---

site_id	SWS_FT_FI18
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:27605664, ECO:0000305|PubMed:23537388

Chain	Residue	Details
A3	GLU40
A3	GLY45
A3	SER441

---

site_id	SWS_FT_FI19
Number of Residues	3
Details	BINDING: axial binding residue => ECO:0000269|PubMed:20385840, ECO:0000269|PubMed:8638158

Chain	Residue	Details
A3	HIS61
A3	HIS376
A3	HIS378

---

site_id	SWS_FT_FI20
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:20385840, ECO:0000269|PubMed:8638158

Chain	Residue	Details
A3	HIS240
A3	HIS290
A3	HIS291
A3	HIS368
A3	ASP369

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A3	TYR244

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: N-formylmethionine => ECO:0000269|PubMed:2165784

Chain	Residue	Details
A3	MET1

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	CROSSLNK: 1'-histidyl-3'-tyrosine (His-Tyr) => ECO:0000269|PubMed:10338009

Chain	Residue	Details
A3	HIS240
A3	TYR244

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	14
Details	M-CSA 124

Chain	Residue	Details
A3	HIS61	metal ligand
A3	HIS290	metal ligand
A3	HIS291	metal ligand, proton acceptor, proton donor
A3	THR316	proton acceptor, proton donor, proton relay
A3	LYS319	proton acceptor, proton donor, proton relay
A3	ARG438	proton acceptor, proton donor, proton relay
A3	ASP91	proton acceptor, proton donor, proton relay
A3	TRP126	proton acceptor, proton donor, proton relay
A3	SER156	proton acceptor, proton donor, proton relay
A3	SER157	proton acceptor, proton donor, proton relay
A3	HIS240	covalently attached, electrostatic stabiliser, metal ligand, radical stabiliser
A3	GLU242	proton acceptor, proton donor, proton relay
A3	TYR244	covalently attached, hydrogen radical donor, proton acceptor, proton donor, proton relay, single electron acceptor
A3	SER255	proton acceptor, proton donor, proton relay

---