7DKF

Activity optimized supercomplex state4

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
12	0003954	molecular_function	NADH dehydrogenase activity
12	0005739	cellular_component	mitochondrion
12	0005743	cellular_component	mitochondrial inner membrane
12	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
12	0009060	biological_process	aerobic respiration
12	0016020	cellular_component	membrane
12	0032981	biological_process	mitochondrial respiratory chain complex I assembly
12	0045271	cellular_component	respiratory chain complex I
12	1902600	biological_process	proton transmembrane transport
22	0005739	cellular_component	mitochondrion
22	0005743	cellular_component	mitochondrial inner membrane
22	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
22	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
22	0016020	cellular_component	membrane
22	0032981	biological_process	mitochondrial respiratory chain complex I assembly
22	0045271	cellular_component	respiratory chain complex I
22	1902600	biological_process	proton transmembrane transport
32	0005739	cellular_component	mitochondrion
32	0005743	cellular_component	mitochondrial inner membrane
32	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
32	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
32	0016020	cellular_component	membrane
32	0045271	cellular_component	respiratory chain complex I
32	1902600	biological_process	proton transmembrane transport
42	0003954	molecular_function	NADH dehydrogenase activity
42	0005739	cellular_component	mitochondrion
42	0005743	cellular_component	mitochondrial inner membrane
42	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
42	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
42	0009060	biological_process	aerobic respiration
42	0015990	biological_process	electron transport coupled proton transport
42	0016020	cellular_component	membrane
42	0032981	biological_process	mitochondrial respiratory chain complex I assembly
42	0042773	biological_process	ATP synthesis coupled electron transport
42	0045271	cellular_component	respiratory chain complex I
42	0048039	molecular_function	ubiquinone binding
52	0005739	cellular_component	mitochondrion
52	0005743	cellular_component	mitochondrial inner membrane
52	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
52	0016020	cellular_component	membrane
52	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
52	0042773	biological_process	ATP synthesis coupled electron transport
52	0045271	cellular_component	respiratory chain complex I
52	1902600	biological_process	proton transmembrane transport
62	0005739	cellular_component	mitochondrion
62	0005743	cellular_component	mitochondrial inner membrane
62	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
62	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
62	0015990	biological_process	electron transport coupled proton transport
62	0016020	cellular_component	membrane
62	0032981	biological_process	mitochondrial respiratory chain complex I assembly
62	0042773	biological_process	ATP synthesis coupled electron transport
62	0045271	cellular_component	respiratory chain complex I
72	0005739	cellular_component	mitochondrion
72	0005743	cellular_component	mitochondrial inner membrane
72	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
72	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
72	0016020	cellular_component	membrane
72	0032981	biological_process	mitochondrial respiratory chain complex I assembly
72	0045271	cellular_component	respiratory chain complex I
72	1902600	biological_process	proton transmembrane transport
82	0005739	cellular_component	mitochondrion
82	0005743	cellular_component	mitochondrial inner membrane
82	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
82	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
82	0010181	molecular_function	FMN binding
82	0016020	cellular_component	membrane
82	0016491	molecular_function	oxidoreductase activity
82	0045271	cellular_component	respiratory chain complex I
82	0046872	molecular_function	metal ion binding
82	0051287	molecular_function	NAD binding
82	0051536	molecular_function	iron-sulfur cluster binding
82	0051539	molecular_function	4 iron, 4 sulfur cluster binding
82	1902600	biological_process	proton transmembrane transport
92	0016491	molecular_function	oxidoreductase activity
A1	0005739	cellular_component	mitochondrion
A1	0005743	cellular_component	mitochondrial inner membrane
A1	0016020	cellular_component	membrane
A1	0032991	cellular_component	protein-containing complex
A1	0046872	molecular_function	metal ion binding
a2	0005739	cellular_component	mitochondrion
a2	0005743	cellular_component	mitochondrial inner membrane
a2	0016020	cellular_component	membrane
a2	0045271	cellular_component	respiratory chain complex I
A2	0005739	cellular_component	mitochondrion
A2	0005743	cellular_component	mitochondrial inner membrane
A2	0005758	cellular_component	mitochondrial intermembrane space
A2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A2	0009055	molecular_function	electron transfer activity
A2	0016020	cellular_component	membrane
A2	0016491	molecular_function	oxidoreductase activity
A2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
A2	0042773	biological_process	ATP synthesis coupled electron transport
A2	0045271	cellular_component	respiratory chain complex I
A2	0045333	biological_process	cellular respiration
A2	0046872	molecular_function	metal ion binding
A2	0051536	molecular_function	iron-sulfur cluster binding
A2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A2	1902600	biological_process	proton transmembrane transport
A3	0004129	molecular_function	cytochrome-c oxidase activity
A3	0005739	cellular_component	mitochondrion
A3	0005743	cellular_component	mitochondrial inner membrane
A3	0006119	biological_process	oxidative phosphorylation
A3	0009060	biological_process	aerobic respiration
A3	0016020	cellular_component	membrane
A3	0020037	molecular_function	heme binding
A3	0022904	biological_process	respiratory electron transport chain
A3	0045277	cellular_component	respiratory chain complex IV
A3	0046872	molecular_function	metal ion binding
A3	1902600	biological_process	proton transmembrane transport
B1	0004222	molecular_function	metalloendopeptidase activity
B1	0005739	cellular_component	mitochondrion
B1	0005743	cellular_component	mitochondrial inner membrane
B1	0006508	biological_process	proteolysis
B1	0016020	cellular_component	membrane
B1	0045275	cellular_component	respiratory chain complex III
B1	0046872	molecular_function	metal ion binding
B2	0003954	molecular_function	NADH dehydrogenase activity
B2	0005739	cellular_component	mitochondrion
B2	0005743	cellular_component	mitochondrial inner membrane
B2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B2	0016020	cellular_component	membrane
B2	0016491	molecular_function	oxidoreductase activity
B2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
B2	0019826	molecular_function	oxygen sensor activity
B2	0022008	biological_process	neurogenesis
B2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B2	0042063	biological_process	gliogenesis
B2	0045271	cellular_component	respiratory chain complex I
B2	0046872	molecular_function	metal ion binding
B2	0048038	molecular_function	quinone binding
B2	0051287	molecular_function	NAD binding
B2	0051536	molecular_function	iron-sulfur cluster binding
B2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B2	0061351	biological_process	neural precursor cell proliferation
B2	0071453	biological_process	cellular response to oxygen levels
B2	1902600	biological_process	proton transmembrane transport
B3	0004129	molecular_function	cytochrome-c oxidase activity
B3	0005507	molecular_function	copper ion binding
B3	0005739	cellular_component	mitochondrion
B3	0005743	cellular_component	mitochondrial inner membrane
B3	0016020	cellular_component	membrane
B3	0016491	molecular_function	oxidoreductase activity
B3	0022900	biological_process	electron transport chain
B3	0031966	cellular_component	mitochondrial membrane
B3	0042773	biological_process	ATP synthesis coupled electron transport
B3	0045277	cellular_component	respiratory chain complex IV
B3	0046872	molecular_function	metal ion binding
B3	1902600	biological_process	proton transmembrane transport
C1	0005739	cellular_component	mitochondrion
C1	0005743	cellular_component	mitochondrial inner membrane
C1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C1	0008121	molecular_function	quinol-cytochrome-c reductase activity
C1	0009055	molecular_function	electron transfer activity
C1	0016020	cellular_component	membrane
C1	0016491	molecular_function	oxidoreductase activity
C1	0020037	molecular_function	heme binding
C1	0022904	biological_process	respiratory electron transport chain
C1	0031966	cellular_component	mitochondrial membrane
C1	0045275	cellular_component	respiratory chain complex III
C1	0046872	molecular_function	metal ion binding
C1	0048039	molecular_function	ubiquinone binding
C1	1902600	biological_process	proton transmembrane transport
c2	0005739	cellular_component	mitochondrion
c2	0005743	cellular_component	mitochondrial inner membrane
c2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c2	0016020	cellular_component	membrane
c2	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
c2	0045271	cellular_component	respiratory chain complex I
C2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C3	0004129	molecular_function	cytochrome-c oxidase activity
C3	0005739	cellular_component	mitochondrion
C3	0005743	cellular_component	mitochondrial inner membrane
C3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
C3	0008535	biological_process	respiratory chain complex IV assembly
C3	0009055	molecular_function	electron transfer activity
C3	0016020	cellular_component	membrane
C3	0019646	biological_process	aerobic electron transport chain
C3	0022904	biological_process	respiratory electron transport chain
C3	0045277	cellular_component	respiratory chain complex IV
C3	1902600	biological_process	proton transmembrane transport
D1	0005739	cellular_component	mitochondrion
D1	0005743	cellular_component	mitochondrial inner membrane
D1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
D1	0008121	molecular_function	quinol-cytochrome-c reductase activity
D1	0009055	molecular_function	electron transfer activity
D1	0016020	cellular_component	membrane
D1	0020037	molecular_function	heme binding
D1	0045275	cellular_component	respiratory chain complex III
D1	0046872	molecular_function	metal ion binding
D1	1902600	biological_process	proton transmembrane transport
d2	0005739	cellular_component	mitochondrion
d2	0005743	cellular_component	mitochondrial inner membrane
d2	0005758	cellular_component	mitochondrial intermembrane space
d2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
d2	0016020	cellular_component	membrane
d2	0045271	cellular_component	respiratory chain complex I
d2	1902600	biological_process	proton transmembrane transport
D2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D2	0048038	molecular_function	quinone binding
D2	0051536	molecular_function	iron-sulfur cluster binding
D2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D3	0005739	cellular_component	mitochondrion
D3	0005743	cellular_component	mitochondrial inner membrane
D3	0006119	biological_process	oxidative phosphorylation
D3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
D3	0016020	cellular_component	membrane
D3	0045277	cellular_component	respiratory chain complex IV
E1	0008121	molecular_function	quinol-cytochrome-c reductase activity
E1	0016020	cellular_component	membrane
E1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
e2	0005739	cellular_component	mitochondrion
e2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
E2	0016020	cellular_component	membrane
E2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
E2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E3	0004129	molecular_function	cytochrome-c oxidase activity
E3	0005739	cellular_component	mitochondrion
E3	0005743	cellular_component	mitochondrial inner membrane
E3	0006119	biological_process	oxidative phosphorylation
E3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
E3	0016020	cellular_component	membrane
E3	0045277	cellular_component	respiratory chain complex IV
E3	0046872	molecular_function	metal ion binding
E3	1902600	biological_process	proton transmembrane transport
F1	0005739	cellular_component	mitochondrion
F1	0005743	cellular_component	mitochondrial inner membrane
F1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F1	0016020	cellular_component	membrane
F1	0045275	cellular_component	respiratory chain complex III
f2	0005739	cellular_component	mitochondrion
f2	0005743	cellular_component	mitochondrial inner membrane
f2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
f2	0016020	cellular_component	membrane
f2	0045271	cellular_component	respiratory chain complex I
F2	0005739	cellular_component	mitochondrion
F2	0045271	cellular_component	respiratory chain complex I
F3	0005739	cellular_component	mitochondrion
F3	0005740	cellular_component	mitochondrial envelope
F3	0005743	cellular_component	mitochondrial inner membrane
F3	0006119	biological_process	oxidative phosphorylation
F3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
F3	0016020	cellular_component	membrane
F3	0045277	cellular_component	respiratory chain complex IV
F3	0046872	molecular_function	metal ion binding
G1	0005739	cellular_component	mitochondrion
G1	0005743	cellular_component	mitochondrial inner membrane
G1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G1	0016020	cellular_component	membrane
G1	0021539	biological_process	subthalamus development
G1	0021548	biological_process	pons development
G1	0021680	biological_process	cerebellar Purkinje cell layer development
G1	0021766	biological_process	hippocampus development
G1	0021794	biological_process	thalamus development
G1	0021854	biological_process	hypothalamus development
G1	0021860	biological_process	pyramidal neuron development
G1	0030901	biological_process	midbrain development
G1	0045275	cellular_component	respiratory chain complex III
g2	0005739	cellular_component	mitochondrion
g2	0005743	cellular_component	mitochondrial inner membrane
g2	0016020	cellular_component	membrane
g2	0045271	cellular_component	respiratory chain complex I
G2	0022900	biological_process	electron transport chain
G3	0005739	cellular_component	mitochondrion
G3	0005743	cellular_component	mitochondrial inner membrane
G3	0006119	biological_process	oxidative phosphorylation
G3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
G3	0016020	cellular_component	membrane
G3	0016491	molecular_function	oxidoreductase activity
G3	0030234	molecular_function	enzyme regulator activity
G3	0045277	cellular_component	respiratory chain complex IV
H1	0005739	cellular_component	mitochondrion
H1	0005743	cellular_component	mitochondrial inner membrane
H1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
H1	0016020	cellular_component	membrane
H1	0045275	cellular_component	respiratory chain complex III
H1	0098803	cellular_component	respiratory chain complex
H2	0005739	cellular_component	mitochondrion
H2	0005743	cellular_component	mitochondrial inner membrane
H2	0005758	cellular_component	mitochondrial intermembrane space
H2	0016020	cellular_component	membrane
H2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
H2	0045271	cellular_component	respiratory chain complex I
H3	0005739	cellular_component	mitochondrion
H3	0005743	cellular_component	mitochondrial inner membrane
H3	0006119	biological_process	oxidative phosphorylation
H3	0016020	cellular_component	membrane
H3	0045277	cellular_component	respiratory chain complex IV
I1	0008121	molecular_function	quinol-cytochrome-c reductase activity
i2	0005739	cellular_component	mitochondrion
i2	0045271	cellular_component	respiratory chain complex I
I2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
I3	0005739	cellular_component	mitochondrion
I3	0005743	cellular_component	mitochondrial inner membrane
I3	0006119	biological_process	oxidative phosphorylation
I3	0016020	cellular_component	membrane
I3	0045277	cellular_component	respiratory chain complex IV
J1	0005739	cellular_component	mitochondrion
J1	0005743	cellular_component	mitochondrial inner membrane
J1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J1	0016020	cellular_component	membrane
J1	0045275	cellular_component	respiratory chain complex III
j2	0005737	cellular_component	cytoplasm
j2	0005739	cellular_component	mitochondrion
j2	0005743	cellular_component	mitochondrial inner membrane
j2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
j2	0016020	cellular_component	membrane
j2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
j2	0045271	cellular_component	respiratory chain complex I
J2	0005739	cellular_component	mitochondrion
J2	0005743	cellular_component	mitochondrial inner membrane
J2	0016020	cellular_component	membrane
J2	0045271	cellular_component	respiratory chain complex I
J3	0004129	molecular_function	cytochrome-c oxidase activity
J3	0005739	cellular_component	mitochondrion
J3	0005743	cellular_component	mitochondrial inner membrane
J3	0006119	biological_process	oxidative phosphorylation
J3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
J3	0016020	cellular_component	membrane
J3	0016491	molecular_function	oxidoreductase activity
J3	0031966	cellular_component	mitochondrial membrane
J3	0045277	cellular_component	respiratory chain complex IV
J3	0097250	biological_process	mitochondrial respirasome assembly
J3	0098803	cellular_component	respiratory chain complex
J3	1902600	biological_process	proton transmembrane transport
K1	0005739	cellular_component	mitochondrion
K1	0005743	cellular_component	mitochondrial inner membrane
K1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
K1	0016020	cellular_component	membrane
K1	0045275	cellular_component	respiratory chain complex III
K2	0005739	cellular_component	mitochondrion
K2	0005743	cellular_component	mitochondrial inner membrane
K2	0016020	cellular_component	membrane
K2	0031966	cellular_component	mitochondrial membrane
K2	0045271	cellular_component	respiratory chain complex I
K3	0005739	cellular_component	mitochondrion
K3	0005743	cellular_component	mitochondrial inner membrane
K3	0006119	biological_process	oxidative phosphorylation
K3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
K3	0007417	biological_process	central nervous system development
K3	0016020	cellular_component	membrane
K3	0045277	cellular_component	respiratory chain complex IV
L2	0005739	cellular_component	mitochondrion
L2	0005743	cellular_component	mitochondrial inner membrane
L2	0016020	cellular_component	membrane
L2	0045271	cellular_component	respiratory chain complex I
L3	0005739	cellular_component	mitochondrion
L3	0005743	cellular_component	mitochondrial inner membrane
L3	0006119	biological_process	oxidative phosphorylation
L3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
L3	0016020	cellular_component	membrane
L3	0045277	cellular_component	respiratory chain complex IV
M1	0005739	cellular_component	mitochondrion
M1	0005743	cellular_component	mitochondrial inner membrane
M1	0016020	cellular_component	membrane
M1	0032991	cellular_component	protein-containing complex
M1	0046872	molecular_function	metal ion binding
M2	0006633	biological_process	fatty acid biosynthetic process
M3	0005739	cellular_component	mitochondrion
M3	0005743	cellular_component	mitochondrial inner membrane
M3	0006119	biological_process	oxidative phosphorylation
M3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
M3	0016020	cellular_component	membrane
M3	0045277	cellular_component	respiratory chain complex IV
N1	0004222	molecular_function	metalloendopeptidase activity
N1	0005739	cellular_component	mitochondrion
N1	0005743	cellular_component	mitochondrial inner membrane
N1	0006508	biological_process	proteolysis
N1	0016020	cellular_component	membrane
N1	0045275	cellular_component	respiratory chain complex III
N1	0046872	molecular_function	metal ion binding
N2	0005739	cellular_component	mitochondrion
N2	0005743	cellular_component	mitochondrial inner membrane
N2	0016020	cellular_component	membrane
N2	0022904	biological_process	respiratory electron transport chain
N2	0045271	cellular_component	respiratory chain complex I
O1	0005739	cellular_component	mitochondrion
O1	0005743	cellular_component	mitochondrial inner membrane
O1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
O1	0008121	molecular_function	quinol-cytochrome-c reductase activity
O1	0009055	molecular_function	electron transfer activity
O1	0016020	cellular_component	membrane
O1	0016491	molecular_function	oxidoreductase activity
O1	0020037	molecular_function	heme binding
O1	0022904	biological_process	respiratory electron transport chain
O1	0031966	cellular_component	mitochondrial membrane
O1	0045275	cellular_component	respiratory chain complex III
O1	0046872	molecular_function	metal ion binding
O1	0048039	molecular_function	ubiquinone binding
O1	1902600	biological_process	proton transmembrane transport
O2	0005739	cellular_component	mitochondrion
O2	0005743	cellular_component	mitochondrial inner membrane
O2	0016020	cellular_component	membrane
O2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
O2	0045271	cellular_component	respiratory chain complex I
P1	0005739	cellular_component	mitochondrion
P1	0005743	cellular_component	mitochondrial inner membrane
P1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
P1	0008121	molecular_function	quinol-cytochrome-c reductase activity
P1	0009055	molecular_function	electron transfer activity
P1	0016020	cellular_component	membrane
P1	0020037	molecular_function	heme binding
P1	0045275	cellular_component	respiratory chain complex III
P1	0046872	molecular_function	metal ion binding
P1	1902600	biological_process	proton transmembrane transport
P2	0005739	cellular_component	mitochondrion
P2	0005743	cellular_component	mitochondrial inner membrane
P2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
P2	0016020	cellular_component	membrane
P2	0016491	molecular_function	oxidoreductase activity
P2	0042773	biological_process	ATP synthesis coupled electron transport
P2	0045271	cellular_component	respiratory chain complex I
Q1	0008121	molecular_function	quinol-cytochrome-c reductase activity
Q1	0016020	cellular_component	membrane
Q1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Q2	0005739	cellular_component	mitochondrion
Q2	0005743	cellular_component	mitochondrial inner membrane
Q2	0005758	cellular_component	mitochondrial intermembrane space
Q2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
Q2	0016020	cellular_component	membrane
Q2	0045271	cellular_component	respiratory chain complex I
R1	0005739	cellular_component	mitochondrion
R1	0005743	cellular_component	mitochondrial inner membrane
R1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
R1	0016020	cellular_component	membrane
R1	0045275	cellular_component	respiratory chain complex III
R2	0003954	molecular_function	NADH dehydrogenase activity
R2	0005739	cellular_component	mitochondrion
R2	0005743	cellular_component	mitochondrial inner membrane
R2	0005759	cellular_component	mitochondrial matrix
R2	0006744	biological_process	ubiquinone biosynthetic process
R2	0007623	biological_process	circadian rhythm
R2	0031966	cellular_component	mitochondrial membrane
R2	0044877	molecular_function	protein-containing complex binding
R2	0045271	cellular_component	respiratory chain complex I
S1	0005739	cellular_component	mitochondrion
S1	0005743	cellular_component	mitochondrial inner membrane
S1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
S1	0016020	cellular_component	membrane
S1	0021539	biological_process	subthalamus development
S1	0021548	biological_process	pons development
S1	0021680	biological_process	cerebellar Purkinje cell layer development
S1	0021766	biological_process	hippocampus development
S1	0021794	biological_process	thalamus development
S1	0021854	biological_process	hypothalamus development
S1	0021860	biological_process	pyramidal neuron development
S1	0030901	biological_process	midbrain development
S1	0045275	cellular_component	respiratory chain complex III
S2	0005737	cellular_component	cytoplasm
S2	0005739	cellular_component	mitochondrion
S2	0005759	cellular_component	mitochondrial matrix
S2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S2	0045271	cellular_component	respiratory chain complex I
T1	0005739	cellular_component	mitochondrion
T1	0005743	cellular_component	mitochondrial inner membrane
T1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
T1	0016020	cellular_component	membrane
T1	0045275	cellular_component	respiratory chain complex III
T1	0098803	cellular_component	respiratory chain complex
T2	0005739	cellular_component	mitochondrion
T2	0005743	cellular_component	mitochondrial inner membrane
T2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
T2	0016020	cellular_component	membrane
T2	0045271	cellular_component	respiratory chain complex I
U1	0008121	molecular_function	quinol-cytochrome-c reductase activity
U2	0005739	cellular_component	mitochondrion
U2	0005743	cellular_component	mitochondrial inner membrane
U2	0016020	cellular_component	membrane
U2	0045271	cellular_component	respiratory chain complex I
V1	0005739	cellular_component	mitochondrion
V1	0005743	cellular_component	mitochondrial inner membrane
V1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
V1	0016020	cellular_component	membrane
V1	0045275	cellular_component	respiratory chain complex III
V2	0005634	cellular_component	nucleus
V2	0005654	cellular_component	nucleoplasm
V2	0005737	cellular_component	cytoplasm
V2	0005739	cellular_component	mitochondrion
V2	0005743	cellular_component	mitochondrial inner membrane
V2	0006915	biological_process	apoptotic process
V2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V2	0016020	cellular_component	membrane
V2	0045271	cellular_component	respiratory chain complex I
V2	0045892	biological_process	negative regulation of DNA-templated transcription
V2	1902600	biological_process	proton transmembrane transport
W1	0005739	cellular_component	mitochondrion
W1	0005743	cellular_component	mitochondrial inner membrane
W1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
W1	0016020	cellular_component	membrane
W1	0045275	cellular_component	respiratory chain complex III
W2	0006633	biological_process	fatty acid biosynthetic process
X2	0005739	cellular_component	mitochondrion
X2	0005743	cellular_component	mitochondrial inner membrane
X2	0016020	cellular_component	membrane
X2	0045271	cellular_component	respiratory chain complex I
Y2	0005743	cellular_component	mitochondrial inner membrane
Y2	0045271	cellular_component	respiratory chain complex I
Z2	0005739	cellular_component	mitochondrion
Z2	0005743	cellular_component	mitochondrial inner membrane
Z2	0016020	cellular_component	membrane
Z2	0022900	biological_process	electron transport chain
Z2	0045271	cellular_component	respiratory chain complex I

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
M2	ASP39-MET54

---

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
M2	ASP64-ILE76

---

site_id	PS00077
Number of Residues	56
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwa.HH

Chain	Residue	Details
A3	TRP236-HIS291

---

site_id	PS00078
Number of Residues	49
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. VlHswavpslglktdaipgrlnqttlmssrpglyygq......CseiCgsnHsfM

Chain	Residue	Details
B3	VAL159-MET207

---

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryensnnlGtSHLLRLAsSlTT

Chain	Residue	Details
B1	GLY54-THR77

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
E2	CYS113-PRO124
E2	CYS152-PRO163

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
B2	LEU116-LYS127

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL

Chain	Residue	Details
C2	GLU169-LEU190

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
A2	PRO61-CYS78

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
A2	CYS128-GLN140

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
A2	ARG175-PHE185

---

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
82	GLY200-SER215

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
82	GLU377-GLY388

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE

Chain	Residue	Details
12	GLY44-GLU59

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
12	PRO197-GLY210

---

site_id	PS00848
Number of Residues	23
Details	COX5B_1 Cytochrome c oxidase subunit Vb, zinc binding region signature. VIWfwlhkgeaqrCpsCGthYKL

Chain	Residue	Details
F3	VAL69-LEU91

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
92	ASP166-PRO184

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
D2	GLY172-PRO188

---

site_id	PS01329
Number of Residues	18
Details	COX6A Cytochrome c oxidase subunit VIa signature. IRtKpFsWGDGnHTfFhN

Chain	Residue	Details
G3	ILE55-ASN72

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P99028

Chain	Residue	Details
H1	LYS29
62	LEU310-CYS330
62	MET366-LEU386
62	LEU413-GLY433
62	LEU457-ILE477
62	MET482-LEU502
62	GLY582-PHE602
O1	TYR347-PRO367
H1	LYS72
T1	LYS29
T1	LYS72
A3	SER401-ASN406
A3	LYS479-LYS514
62	LEU213-LEU233
62	THR241-ILE261
62	ILE273-LEU293

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	TRANSMEM: Helical => ECO:0000269|PubMed:9651245

Chain	Residue	Details
G1	ARG39-GLU67
S1	ARG39-GLU67
F3	LYS90
R1	LYS18
R1	LYS82
R1	LYS95

---

site_id	SWS_FT_FI3
Number of Residues	26
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269|PubMed:9651245

Chain	Residue	Details
G1	LYS68-ARG81
S1	LYS68-ARG81
R1	LYS77
R1	LYS87

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q9CQ69

Chain	Residue	Details
G1	LYS32
Q1	SER163
S1	LYS32
E1	CYS158
E1	HIS161
E1	SER163
Q1	CYS139
Q1	HIS141
Q1	CYS158
Q1	HIS161

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P13073

Chain	Residue	Details
D3	LYS31
B3	CYS196
B3	GLU198
B3	CYS200
B3	HIS204
B3	MET207

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P10888

Chain	Residue	Details
D3	SER34
D3	SER36
A3	VAL287-ASP298

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P19783

Chain	Residue	Details
D3	LYS45

---

site_id	SWS_FT_FI8
Number of Residues	32
Details	TRANSMEM: Helical; Name=VI => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	GLY191-LEU223

---

site_id	SWS_FT_FI9
Number of Residues	23
Details	TRANSMEM: Helical; Name=VII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	PHE233-ILE256

---

site_id	SWS_FT_FI10
Number of Residues	16
Details	TRANSMEM: Helical; Name=VII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	TYR270-ILE286

---

site_id	SWS_FT_FI11
Number of Residues	28
Details	TRANSMEM: Helical; Name=VIII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	VAL299-LEU327

---

site_id	SWS_FT_FI12
Number of Residues	7
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	HIS328-SER335

---

site_id	SWS_FT_FI13
Number of Residues	21
Details	TRANSMEM: Helical; Name=IX => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	PRO336-VAL357

---

site_id	SWS_FT_FI14
Number of Residues	24
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	LEU358-THR370
A3	SER434-ALA446

---

site_id	SWS_FT_FI15
Number of Residues	29
Details	TRANSMEM: Helical; Name=X => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	TYR371-PHE400

---

site_id	SWS_FT_FI16
Number of Residues	26
Details	TRANSMEM: Helical; Name=XI => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	ASP407-LEU433

---

site_id	SWS_FT_FI17
Number of Residues	31
Details	TRANSMEM: Helical; Name=XII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A3	TYR447-SER478

---

site_id	SWS_FT_FI18
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:27605664, ECO:0000305|PubMed:23537388

Chain	Residue	Details
A3	GLU40
A3	GLY45
A3	SER441

---

site_id	SWS_FT_FI19
Number of Residues	3
Details	BINDING: axial binding residue => ECO:0000269|PubMed:20385840, ECO:0000269|PubMed:8638158

Chain	Residue	Details
A3	HIS61
A3	HIS376
A3	HIS378

---

site_id	SWS_FT_FI20
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:20385840, ECO:0000269|PubMed:8638158

Chain	Residue	Details
A3	HIS240
A3	HIS290
A3	HIS291
A3	HIS368
A3	ASP369

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A3	TYR244

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: N-formylmethionine => ECO:0000269|PubMed:2165784

Chain	Residue	Details
A3	MET1

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	CROSSLNK: 1'-histidyl-3'-tyrosine (His-Tyr) => ECO:0000269|PubMed:10338009

Chain	Residue	Details
A3	HIS240
A3	TYR244

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	14
Details	M-CSA 124

Chain

Residue

Details

---