7DHG

Crystal structure of SARS-CoV-2 Orf9b complex with human TOM70

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005515	molecular_function	protein binding
B	0030430	cellular_component	host cell cytoplasm
B	0031966	cellular_component	mitochondrial membrane
B	0033650	cellular_component	host cell mitochondrion
B	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
B	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
B	0042802	molecular_function	identical protein binding
B	0050687	biological_process	negative regulation of defense response to virus
B	0052031	biological_process	symbiont-mediated perturbation of host defense response
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0090258	biological_process	negative regulation of mitochondrial fission
B	0140311	molecular_function	protein sequestering activity
B	2000786	biological_process	positive regulation of autophagosome assembly
C	0002218	biological_process	activation of innate immune response
C	0002230	biological_process	positive regulation of defense response to virus by host
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0005742	cellular_component	mitochondrial outer membrane translocase complex
C	0006626	biological_process	obsolete protein targeting to mitochondrion
C	0008320	molecular_function	protein transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0030150	biological_process	protein import into mitochondrial matrix
C	0030674	molecular_function	protein-macromolecule adaptor activity
C	0030943	molecular_function	mitochondrion targeting sequence binding
C	0031966	cellular_component	mitochondrial membrane
C	0032728	biological_process	positive regulation of interferon-beta production
C	0042981	biological_process	regulation of apoptotic process
C	0045039	biological_process	protein insertion into mitochondrial inner membrane
C	0045040	biological_process	protein insertion into mitochondrial outer membrane
C	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
C	0070062	cellular_component	extracellular exosome
C	0097068	biological_process	response to thyroxine
C	0098586	biological_process	cellular response to virus
C	1903955	biological_process	obsolete positive regulation of protein targeting to mitochondrion

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	33
Details	Repeat: {"description":"TPR 1"}

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site_id	SWS_FT_FI2
Number of Residues	33
Details	Repeat: {"description":"TPR 2"}

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site_id	SWS_FT_FI3
Number of Residues	33
Details	Repeat: {"description":"TPR 4"}

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site_id	SWS_FT_FI4
Number of Residues	33
Details	Repeat: {"description":"TPR 5"}

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site_id	SWS_FT_FI5
Number of Residues	33
Details	Repeat: {"description":"TPR 6"}

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site_id	SWS_FT_FI6
Number of Residues	35
Details	Repeat: {"description":"TPR 7"}

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site_id	SWS_FT_FI7
Number of Residues	33
Details	Repeat: {"description":"TPR 8"}

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site_id	SWS_FT_FI8
Number of Residues	33
Details	Repeat: {"description":"TPR 9"}

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site_id	SWS_FT_FI9
Number of Residues	33
Details	Repeat: {"description":"TPR 10"}

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site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI12
Number of Residues	8
Details	Motif: {"description":"Nuclear export signal","evidences":[{"source":"UniProtKB","id":"P59636","evidenceCode":"ECO:0000250"}]}

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