Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7DH0

Activity optimized complex I (open form)

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003954	molecular_function	NADH dehydrogenase activity
1	0005743	cellular_component	mitochondrial inner membrane
1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1	0009060	biological_process	aerobic respiration
1	0016020	cellular_component	membrane
1	0022904	biological_process	respiratory electron transport chain
1	0032981	biological_process	mitochondrial respiratory chain complex I assembly
1	0045271	cellular_component	respiratory chain complex I
1	1902600	biological_process	proton transmembrane transport
2	0005743	cellular_component	mitochondrial inner membrane
2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
2	0022904	biological_process	respiratory electron transport chain
2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
2	0045271	cellular_component	respiratory chain complex I
2	1902600	biological_process	proton transmembrane transport
3	0005743	cellular_component	mitochondrial inner membrane
3	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3	0022904	biological_process	respiratory electron transport chain
3	0045271	cellular_component	respiratory chain complex I
3	1902600	biological_process	proton transmembrane transport
4	0003954	molecular_function	NADH dehydrogenase activity
4	0005743	cellular_component	mitochondrial inner membrane
4	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4	0009060	biological_process	aerobic respiration
4	0015990	biological_process	electron transport coupled proton transport
4	0022904	biological_process	respiratory electron transport chain
4	0032981	biological_process	mitochondrial respiratory chain complex I assembly
4	0042773	biological_process	ATP synthesis coupled electron transport
4	0045271	cellular_component	respiratory chain complex I
4	0048039	molecular_function	ubiquinone binding
5	0005743	cellular_component	mitochondrial inner membrane
5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
5	0022904	biological_process	respiratory electron transport chain
5	0042773	biological_process	ATP synthesis coupled electron transport
5	0045271	cellular_component	respiratory chain complex I
5	1902600	biological_process	proton transmembrane transport
6	0005743	cellular_component	mitochondrial inner membrane
6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
6	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6	0015990	biological_process	electron transport coupled proton transport
6	0022904	biological_process	respiratory electron transport chain
6	0032981	biological_process	mitochondrial respiratory chain complex I assembly
6	0042773	biological_process	ATP synthesis coupled electron transport
6	0045271	cellular_component	respiratory chain complex I
7	0005739	cellular_component	mitochondrion
7	0005743	cellular_component	mitochondrial inner membrane
7	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
7	0022904	biological_process	respiratory electron transport chain
7	0032981	biological_process	mitochondrial respiratory chain complex I assembly
7	0045271	cellular_component	respiratory chain complex I
7	1902600	biological_process	proton transmembrane transport
8	0005743	cellular_component	mitochondrial inner membrane
8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
8	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
8	0010181	molecular_function	FMN binding
8	0016491	molecular_function	oxidoreductase activity
8	0022904	biological_process	respiratory electron transport chain
8	0045271	cellular_component	respiratory chain complex I
8	0046872	molecular_function	metal ion binding
8	0051287	molecular_function	NAD binding
8	0051536	molecular_function	iron-sulfur cluster binding
8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
8	1902600	biological_process	proton transmembrane transport
9	0016491	molecular_function	oxidoreductase activity
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0022904	biological_process	respiratory electron transport chain
a	0045271	cellular_component	respiratory chain complex I
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0022904	biological_process	respiratory electron transport chain
A	0032981	biological_process	mitochondrial respiratory chain complex I assembly
A	0042773	biological_process	ATP synthesis coupled electron transport
A	0045271	cellular_component	respiratory chain complex I
A	0045333	biological_process	cellular respiration
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	1902600	biological_process	proton transmembrane transport
B	0003954	molecular_function	NADH dehydrogenase activity
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0016491	molecular_function	oxidoreductase activity
B	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
B	0019826	molecular_function	oxygen sensor activity
B	0022008	biological_process	neurogenesis
B	0022904	biological_process	respiratory electron transport chain
B	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B	0042063	biological_process	gliogenesis
B	0045271	cellular_component	respiratory chain complex I
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding
B	0051287	molecular_function	NAD binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0061351	biological_process	neural precursor cell proliferation
B	0071453	biological_process	cellular response to oxygen levels
B	1902600	biological_process	proton transmembrane transport
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c	0022904	biological_process	respiratory electron transport chain
c	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
c	0045271	cellular_component	respiratory chain complex I
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
d	0005739	cellular_component	mitochondrion
d	0005743	cellular_component	mitochondrial inner membrane
d	0005758	cellular_component	mitochondrial intermembrane space
d	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
d	0022904	biological_process	respiratory electron transport chain
d	0045271	cellular_component	respiratory chain complex I
d	1902600	biological_process	proton transmembrane transport
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0048038	molecular_function	quinone binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
e	0005739	cellular_component	mitochondrion
e	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
E	0016020	cellular_component	membrane
E	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
f	0022904	biological_process	respiratory electron transport chain
f	0045271	cellular_component	respiratory chain complex I
F	0005739	cellular_component	mitochondrion
F	0045271	cellular_component	respiratory chain complex I
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0022904	biological_process	respiratory electron transport chain
g	0045271	cellular_component	respiratory chain complex I
G	0022900	biological_process	electron transport chain
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005758	cellular_component	mitochondrial intermembrane space
H	0022904	biological_process	respiratory electron transport chain
H	0032981	biological_process	mitochondrial respiratory chain complex I assembly
H	0045271	cellular_component	respiratory chain complex I
i	0005739	cellular_component	mitochondrion
i	0045271	cellular_component	respiratory chain complex I
I	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
j	0005737	cellular_component	cytoplasm
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
j	0022904	biological_process	respiratory electron transport chain
j	0032981	biological_process	mitochondrial respiratory chain complex I assembly
j	0045271	cellular_component	respiratory chain complex I
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0022904	biological_process	respiratory electron transport chain
J	0045271	cellular_component	respiratory chain complex I
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0022904	biological_process	respiratory electron transport chain
K	0031966	cellular_component	mitochondrial membrane
K	0045271	cellular_component	respiratory chain complex I
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0022904	biological_process	respiratory electron transport chain
L	0045271	cellular_component	respiratory chain complex I
M	0006633	biological_process	fatty acid biosynthetic process
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0022904	biological_process	respiratory electron transport chain
N	0045271	cellular_component	respiratory chain complex I
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0022904	biological_process	respiratory electron transport chain
O	0032981	biological_process	mitochondrial respiratory chain complex I assembly
O	0045271	cellular_component	respiratory chain complex I
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
P	0016491	molecular_function	oxidoreductase activity
P	0022904	biological_process	respiratory electron transport chain
P	0042773	biological_process	ATP synthesis coupled electron transport
P	0045271	cellular_component	respiratory chain complex I
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005758	cellular_component	mitochondrial intermembrane space
Q	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
Q	0022904	biological_process	respiratory electron transport chain
Q	0045271	cellular_component	respiratory chain complex I
R	0003954	molecular_function	NADH dehydrogenase activity
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005759	cellular_component	mitochondrial matrix
R	0006744	biological_process	ubiquinone biosynthetic process
R	0007623	biological_process	circadian rhythm
R	0022904	biological_process	respiratory electron transport chain
R	0031966	cellular_component	mitochondrial membrane
R	0044877	molecular_function	protein-containing complex binding
R	0045271	cellular_component	respiratory chain complex I
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005759	cellular_component	mitochondrial matrix
S	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S	0022904	biological_process	respiratory electron transport chain
S	0045271	cellular_component	respiratory chain complex I
S	1902600	biological_process	proton transmembrane transport
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
T	0022904	biological_process	respiratory electron transport chain
T	0045271	cellular_component	respiratory chain complex I
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0016020	cellular_component	membrane
U	0022904	biological_process	respiratory electron transport chain
U	0045271	cellular_component	respiratory chain complex I
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0006915	biological_process	apoptotic process
V	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V	0022904	biological_process	respiratory electron transport chain
V	0045271	cellular_component	respiratory chain complex I
V	0045892	biological_process	negative regulation of DNA-templated transcription
V	1902600	biological_process	proton transmembrane transport
W	0006633	biological_process	fatty acid biosynthetic process
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0022904	biological_process	respiratory electron transport chain
X	0045271	cellular_component	respiratory chain complex I
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0045271	cellular_component	respiratory chain complex I
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0022900	biological_process	electron transport chain
Z	0022904	biological_process	respiratory electron transport chain
Z	0045271	cellular_component	respiratory chain complex I

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue 3PE 2 401

Chain	Residue
2	PRO238
2	ILE239
4	TRP16
4	THR90

site_id	AC2
Number of Residues	10
Details	binding site for residue CDL 4 501

Chain	Residue
6	TRP66
b	GLY79
b	ALA83
b	ILE84
h	ALA107
4	LEU446
4	LEU449
4	ASN450
6	MET20
6	SER23

site_id	AC3
Number of Residues	5
Details	binding site for residue 3PE 4 502

Chain	Residue
2	ILE276
4	TYR166
4	SER191
4	PHE194
T	TRP133

site_id	AC4
Number of Residues	10
Details	binding site for residue FMN 8 501

Chain	Residue
8	GLY89
8	LYS98
8	ASN116
8	ASP118
8	GLU119
8	GLY120
8	CYS206
8	GLY207
8	ALA243
8	ASN244

site_id	AC5
Number of Residues	9
Details	binding site for residue SF4 8 502

Chain	Residue
8	TYR204
8	CYS379
8	GLY380
8	GLN381
8	CYS382
8	CYS385
8	THR423
8	ILE424
8	CYS425

site_id	AC6
Number of Residues	8
Details	binding site for residue FES 9 301

Chain	Residue
9	CYS135
9	THR137
9	CYS140
9	CYS176
9	LEU177
9	GLY178
9	ALA179
9	CYS180

site_id	AC7
Number of Residues	9
Details	binding site for residue SF4 A 801

Chain	Residue
A	HIS124
A	ASP127
A	CYS128
A	CYS131
A	CYS137
A	LEU139
A	GLN140
A	ARG175
A	GLY229

site_id	AC8
Number of Residues	9
Details	binding site for residue SF4 A 802

Chain	Residue
A	CYS176
A	GLN178
A	CYS179
A	ARG181
A	CYS182
A	VAL206
A	CYS226
A	PRO227
A	LEU231

site_id	AC9
Number of Residues	7
Details	binding site for residue FES A 803

Chain	Residue
A	CYS64
A	GLY73
A	CYS75
A	ARG76
A	MET77
A	CYS78
A	CYS92

site_id	AD1
Number of Residues	11
Details	binding site for residue 3PE B 501

Chain	Residue
1	PRO180
1	ALA182
1	MET183
1	MET184
1	PHE186
1	TYR277
1	PHE293
B	ARG266
E	THR60
E	LEU61
E	TRP63

site_id	AD2
Number of Residues	7
Details	binding site for residue SF4 D 301

Chain	Residue
B	ARG138
D	ALA90
D	CYS91
D	CYS92
D	CYS156
D	CYS186
D	PRO187

site_id	AD3
Number of Residues	11
Details	binding site for residue SF4 E 301

Chain	Residue
E	GLU169
E	HIS101
E	CYS123
E	PRO124
E	CYS152
E	ILE153
E	TYR154
E	CYS155
E	GLY156
E	PHE157
E	CYS158

site_id	AD4
Number of Residues	11
Details	binding site for residue SF4 E 302

Chain	Residue
E	CYS113
E	ILE114
E	ALA115
E	CYS116
E	LYS117
E	LEU118
E	CYS119
E	ILE130
E	CYS162
E	ALA166
E	ILE167

site_id	AD5
Number of Residues	3
Details	binding site for residue ZN I 300

Chain	Residue
I	CYS87
I	HIS96
I	CYS115

site_id	AD6
Number of Residues	15
Details	binding site for residue NAP R 601

Chain	Residue
D	ARG215
R	THR62
R	GLY63
R	PHE64
R	LEU65
R	ARG85
R	GLU87
R	LEU129
R	VAL130
R	GLY131
R	ARG132
R	ILE167
R	TYR180
R	ALA204
R	ILE206

site_id	AD7
Number of Residues	1
Details	binding site for residue PC1 S 401

Chain	Residue
S	MET284

site_id	AD8
Number of Residues	3
Details	binding site for residue PC1 j 201

Chain	Residue
H	PHE4
j	PHE11
j	GLN12

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
W	ASP107-MET122

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
W	ASP132-ILE144

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
E	CYS113-PRO124
E	CYS152-PRO163

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
B	LEU116-LYS127

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL

Chain	Residue	Details
C	GLU169-LEU190

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
A	PRO61-CYS78

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
A	CYS128-GLN140

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
A	ARG175-PHE185

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
8	GLY200-SER215

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
8	GLU377-GLY388

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE

Chain	Residue	Details
1	GLY44-GLU59

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
1	PRO197-GLY210

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
9	ASP166-PRO184

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
D	GLY172-PRO188

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1401
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"N-formylmethionine","evidences":[{"source":"PubMed","id":"17060615","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	57
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27509854","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5LC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LDX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q91YT0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q91YT0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"Q91YT0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D6J6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by SRC","evidences":[{"source":"UniProtKB","id":"P19404","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	78
Details	Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	39
Details	Domain: {"description":"4Fe-4S His(Cys)3-ligated-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	56
Details	Domain: {"description":"4Fe-4S Mo/W bis-MGD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01004","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q56223","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q91VD9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Symmetric dimethylarginine","evidences":[{"source":"PubMed","id":"23836892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Hydroxyarginine","evidences":[{"source":"PubMed","id":"23836892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	29
Details	Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	29
Details	Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P56181","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	121
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20433953","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI25
Number of Residues	86
Details	Domain: {"description":"CHCH","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI26
Number of Residues	30
Details	Motif: {"description":"Cx9C motif 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI27
Number of Residues	30
Details	Motif: {"description":"Cx9C motif 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI28
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CQ75","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CQ75","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI30
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q16718","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI31
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CPP6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q63362","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI33
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CPP6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI34
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9Z1P6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI35
Number of Residues	41
Details	Domain: {"description":"CHCH 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI36
Number of Residues	43
Details	Domain: {"description":"CHCH 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI37
Number of Residues	10
Details	Motif: {"description":"Cx9C motif 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI38
Number of Residues	10
Details	Motif: {"description":"Cx9C motif 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI39
Number of Residues	24
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI40
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9DC69","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI41
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9DC69","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI42
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q99LC3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI43
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PINK1","evidences":[{"source":"UniProtKB","id":"Q99LC3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI44
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"12381726","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17060615","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI45
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"9827566","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI46
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CR21","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI47
Number of Residues	2
Details	Modified residue: {"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1907568","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI48
Number of Residues	75
Details	Domain: {"description":"Carrier","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI49
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CQZ6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O95168","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI51
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q3UIU2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI52
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9CR61","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI53
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9Y6M9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI54
Number of Residues	1
Details	Modified residue: {"description":"N-formylmethionine","evidences":[{"source":"PubMed","id":"17060615","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3141400","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI55
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O96000","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)