7DCE
Cryo-EM structure of human XKR8-basigin complex bound to Fab fragment
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0002513 | biological_process | tolerance induction to self antigen |
| X | 0005737 | cellular_component | cytoplasm |
| X | 0005886 | cellular_component | plasma membrane |
| X | 0006915 | biological_process | apoptotic process |
| X | 0016020 | cellular_component | membrane |
| X | 0017128 | molecular_function | phospholipid scramblase activity |
| X | 0043652 | biological_process | engulfment of apoptotic cell |
| X | 0045663 | biological_process | positive regulation of myoblast differentiation |
| X | 0048471 | cellular_component | perinuclear region of cytoplasm |
| X | 0051649 | biological_process | establishment of localization in cell |
| X | 0070782 | biological_process | phosphatidylserine exposure on apoptotic cell surface |
| X | 0097350 | biological_process | neutrophil clearance |
| X | 1902742 | biological_process | apoptotic process involved in development |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR193-HIS199 | |
| L | TYR196-HIS202 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 168 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| X | MET1-ASP12 | |
| X | ARG69-ARG158 | |
| X | SER222-ALA223 | |
| X | GLU278-ARG284 | |
| X | ARG334-GLY395 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 157 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| X | LEU13-ALA33 | |
| X | LEU48-LEU68 | |
| X | ALA159-LEU179 | |
| X | VAL201-PHE221 | |
| X | LEU224-VAL244 | |
| X | LEU260-ALA277 | |
| X | ALA285-THR305 | |
| X | GLY313-LEU333 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 53 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| X | ALA34-ALA47 | |
| X | ASP180-SER200 | |
| X | TRP245-TRP259 | |
| X | HIS306-SER312 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by caspase-3 => ECO:0000305|PubMed:23845944 |
| Chain | Residue | Details |
| X | ASP355 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8C0T0 |
| Chain | Residue | Details |
| X | SER362 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8C0T0 |
| Chain | Residue | Details |
| X | THR375 |
