7DCE
Cryo-EM structure of human XKR8-basigin complex bound to Fab fragment
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0005886 | cellular_component | plasma membrane |
| X | 0016020 | cellular_component | membrane |
| X | 0017128 | molecular_function | phospholipid scramblase activity |
| X | 0043652 | biological_process | engulfment of apoptotic cell |
| X | 0045663 | biological_process | positive regulation of myoblast differentiation |
| X | 0048471 | cellular_component | perinuclear region of cytoplasm |
| X | 0070782 | biological_process | phosphatidylserine exposure on apoptotic cell surface |
| X | 0097350 | biological_process | neutrophil clearance |
| X | 0098883 | biological_process | synapse pruning |
| X | 1902742 | biological_process | apoptotic process involved in development |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR193-HIS199 | |
| L | TYR196-HIS202 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 94 |
| Details | Domain: {"description":"Ig-like V-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 38 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 86 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 10 |
| Details | Intramembrane: {"description":"Helical; Name=IH1","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 24 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 14 |
| Details | Intramembrane: {"description":"Helical; Name=IH2","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38364890","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8XEJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34625749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DCE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q8C0T0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
