7DBI

Crystal structure of the peroxisomal acyl-CoA hydrolase MpaH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0016114	biological_process	terpenoid biosynthetic process
A	0016218	molecular_function	polyketide synthase activity
A	0016787	molecular_function	hydrolase activity
A	0017000	biological_process	antibiotic biosynthetic process
A	0047617	molecular_function	fatty acyl-CoA hydrolase activity
A	0072330	biological_process	monocarboxylic acid biosynthetic process
A	0140722	biological_process	mycophenolic acid biosynthetic process
B	0005777	cellular_component	peroxisome
B	0005782	cellular_component	peroxisomal matrix
B	0016114	biological_process	terpenoid biosynthetic process
B	0016218	molecular_function	polyketide synthase activity
B	0016787	molecular_function	hydrolase activity
B	0017000	biological_process	antibiotic biosynthetic process
B	0047617	molecular_function	fatty acyl-CoA hydrolase activity
B	0072330	biological_process	monocarboxylic acid biosynthetic process
B	0140722	biological_process	mycophenolic acid biosynthetic process
C	0005777	cellular_component	peroxisome
C	0005782	cellular_component	peroxisomal matrix
C	0016114	biological_process	terpenoid biosynthetic process
C	0016218	molecular_function	polyketide synthase activity
C	0016787	molecular_function	hydrolase activity
C	0017000	biological_process	antibiotic biosynthetic process
C	0047617	molecular_function	fatty acyl-CoA hydrolase activity
C	0072330	biological_process	monocarboxylic acid biosynthetic process
C	0140722	biological_process	mycophenolic acid biosynthetic process
D	0005777	cellular_component	peroxisome
D	0005782	cellular_component	peroxisomal matrix
D	0016114	biological_process	terpenoid biosynthetic process
D	0016218	molecular_function	polyketide synthase activity
D	0016787	molecular_function	hydrolase activity
D	0017000	biological_process	antibiotic biosynthetic process
D	0047617	molecular_function	fatty acyl-CoA hydrolase activity
D	0072330	biological_process	monocarboxylic acid biosynthetic process
D	0140722	biological_process	mycophenolic acid biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:31209052, ECO:0000269|PubMed:33843134

Chain	Residue	Details
A	SER139
B	SER139
C	SER139
D	SER139

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site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:33843134, ECO:0000305|PubMed:31209052

Chain	Residue	Details
A	ASP163
A	HIS365
B	ASP163
B	HIS365
C	ASP163
C	HIS365
D	ASP163
D	HIS365

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:33843134, ECO:0007744|PDB:7DBL

Chain	Residue	Details
A	VAL60
A	PHE140
B	VAL60
B	PHE140
C	VAL60
C	PHE140
D	VAL60
D	PHE140

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