7DB0
Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in dimedone-bound form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0004769 | molecular_function | steroid delta-isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006694 | biological_process | steroid biosynthetic process |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042632 | biological_process | cholesterol homeostasis |
| A | 0045456 | biological_process | ecdysteroid biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0004769 | molecular_function | steroid delta-isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006694 | biological_process | steroid biosynthetic process |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009636 | biological_process | response to toxic substance |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042632 | biological_process | cholesterol homeostasis |
| B | 0045456 | biological_process | ecdysteroid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue DC1 A 301 |
| Chain | Residue |
| A | PRO15 |
| A | PHE110 |
| A | ASP113 |
| A | SER114 |
| A | THR172 |
| A | HOH409 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 302 |
| Chain | Residue |
| A | TYR147 |
| A | ASN150 |
| A | HOH441 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 303 |
| Chain | Residue |
| A | ASP152 |
| A | PHE153 |
| A | ARG187 |
| A | ALA191 |
| A | HOH447 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 304 |
| Chain | Residue |
| A | LEU27 |
| A | PHE35 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue DMS A 305 |
| Chain | Residue |
| A | ASP28 |
| A | ILE29 |
| A | ASP30 |
| A | PHE81 |
| A | GLN210 |
| A | SER214 |
| A | HOH404 |
| A | HOH411 |
| A | HOH549 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 306 |
| Chain | Residue |
| A | TYR10 |
| A | GLU12 |
| A | LEU33 |
| A | HOH633 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 307 |
| Chain | Residue |
| A | HIS62 |
| A | LEU65 |
| A | HIS76 |
| A | LYS80 |
| A | HOH416 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 308 |
| Chain | Residue |
| A | SER107 |
| A | ARG111 |
| A | ARG112 |
| A | HOH557 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 309 |
| Chain | Residue |
| A | CYS106 |
| A | PHE110 |
| A | HOH528 |
| A | HOH620 |
| B | HOH453 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue DC1 B 301 |
| Chain | Residue |
| B | PRO15 |
| B | PHE110 |
| B | ASP113 |
| B | SER114 |
| B | THR172 |
| B | HOH445 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 302 |
| Chain | Residue |
| B | GLN181 |
| B | HOH478 |
| B | HOH555 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 303 |
| Chain | Residue |
| A | HOH628 |
| B | GLU12 |
| B | LEU33 |
| B | HOH406 |
| B | HOH626 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 304 |
| Chain | Residue |
| A | HIS92 |
| B | HIS62 |
| B | LEU65 |
| B | HIS76 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue DMS B 305 |
| Chain | Residue |
| B | SER56 |
| B | VAL57 |
| B | PRO58 |
| B | THR68 |
| B | ASP69 |
| B | SER70 |
| B | HOH420 |
