7DAX
Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in TDP013-bound form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0004769 | molecular_function | steroid delta-isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006694 | biological_process | steroid biosynthetic process |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042632 | biological_process | cholesterol homeostasis |
| A | 0045456 | biological_process | ecdysteroid biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0004769 | molecular_function | steroid delta-isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006694 | biological_process | steroid biosynthetic process |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009636 | biological_process | response to toxic substance |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042632 | biological_process | cholesterol homeostasis |
| B | 0045456 | biological_process | ecdysteroid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue H1X A 301 |
| Chain | Residue |
| A | ARG13 |
| A | PRO15 |
| A | LEU38 |
| A | SER114 |
| A | MET117 |
| A | SER118 |
| A | VAL121 |
| A | LEU208 |
| A | HOH522 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 302 |
| Chain | Residue |
| A | LEU26 |
| A | PHE35 |
| A | LEU87 |
| A | HOH409 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue DMS A 303 |
| Chain | Residue |
| A | ASP28 |
| A | ILE29 |
| A | ASP30 |
| A | PHE81 |
| A | GLN210 |
| A | SER214 |
| A | HOH438 |
| A | HOH492 |
| A | HOH512 |
| A | HOH545 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 304 |
| Chain | Residue |
| A | GLY84 |
| A | GLN90 |
| A | ARG95 |
| A | HOH519 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue H1X B 401 |
| Chain | Residue |
| A | GLU79 |
| A | TRP88 |
| A | ARG95 |
| A | MET96 |
| B | GLU79 |
| B | TRP88 |
| B | GLN90 |
| B | ARG95 |
| B | HOH510 |
| B | HOH604 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue H1X B 402 |
| Chain | Residue |
| B | ARG13 |
| B | SER14 |
| B | PHE39 |
| B | PHE110 |
| B | SER114 |
| B | MET117 |
| B | SER118 |
| B | HOH502 |
| B | HOH615 |
