7D87

Crystal Structure of zebrafish PHF14-PZP in complex with H3(1-25)

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0000786	cellular_component	nucleosome
E	0003677	molecular_function	DNA binding
E	0030527	molecular_function	structural constituent of chromatin

Functional Information from PROSITE/UniProt

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
E	LYS14-LEU20

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site_id	PS01359
Number of Residues	56
Details	ZF_PHD_1 Zinc finger PHD-type signature. CcvClgdnsedadei..................................IqCdn..Cgvt.VHegCygvdgesdsimssasenstep........................WfCdaC

Chain	Residue	Details
A	CYS288-CYS343

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	61
Details	ZN_FING: PHD-type 1 => ECO:0000255|PROSITE-ProRule:PRU00146

Chain	Residue	Details
A	ILE285-GLY346

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site_id	SWS_FT_FI2
Number of Residues	33
Details	ZN_FING: C2HC pre-PHD-type => ECO:0000255|PROSITE-ProRule:PRU01146

Chain	Residue	Details
A	SER348-VAL381

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site_id	SWS_FT_FI3
Number of Residues	60
Details	ZN_FING: PHD-type 2 => ECO:0000255|PROSITE-ProRule:PRU01146

Chain	Residue	Details
A	LYS405-ALA465

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site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00146, ECO:0000269|PubMed:34365506, ECO:0007744|PDB:7D86, ECO:0007744|PDB:7D87, ECO:0007744|PDB:7D8A

Chain	Residue	Details
A	CYS288
A	CYS291
A	CYS305
A	CYS308
A	HIS313
A	CYS316
A	CYS340
A	CYS343

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site_id	SWS_FT_FI5
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:34365506, ECO:0007744|PDB:7D86, ECO:0007744|PDB:7D87, ECO:0007744|PDB:7D8A

Chain	Residue	Details
A	CYS351
A	CYS437
A	CYS461
A	HIS464
A	CYS354
A	HIS371
A	CYS374
A	CYS407
A	CYS410
A	CYS424
A	CYS429
A	HIS434

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