7D25

Hsp90 alpha N-terminal domain in complex with a 14 compund

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0006457	biological_process	protein folding
A	0016887	molecular_function	ATP hydrolysis activity
A	0051082	molecular_function	unfolded protein binding
A	0140662	molecular_function	ATP-dependent protein folding chaperone

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue GQ6 A 301

Chain	Residue
A	ASN51
A	GQ6302
A	HOH446
A	HOH557
A	HOH561
A	HOH585
A	ALA55
A	ASP93
A	ILE96
A	GLY97
A	MET98
A	PHE138
A	TRP162
A	THR184

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site_id	AC2
Number of Residues	9
Details	binding site for residue GQ6 A 302

Chain	Residue
A	ASN51
A	LEU107
A	ALA111
A	GLY135
A	VAL136
A	GLY137
A	PHE138
A	TYR139
A	GQ6301

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Functional Information from PROSITE/UniProt

site_id	PS00298
Number of Residues	10
Details	HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE

Chain	Residue	Details
A	TYR38-GLU47

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	PHE138
A	ASN51
A	ASP93
A	LYS112

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337

Chain	Residue	Details
A	LYS84
A	LYS58

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