Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7CPR

glutamine synthetase from Drosophila

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0006538	biological_process	L-glutamate catabolic process
A	0006542	biological_process	obsolete glutamine biosynthetic process
A	0007416	biological_process	synapse assembly
A	0016874	molecular_function	ligase activity
A	0043436	biological_process	oxoacid metabolic process
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0006538	biological_process	L-glutamate catabolic process
B	0006542	biological_process	obsolete glutamine biosynthetic process
B	0007416	biological_process	synapse assembly
B	0016874	molecular_function	ligase activity
B	0043436	biological_process	oxoacid metabolic process
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0004356	molecular_function	glutamine synthetase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0006538	biological_process	L-glutamate catabolic process
C	0006542	biological_process	obsolete glutamine biosynthetic process
C	0007416	biological_process	synapse assembly
C	0016874	molecular_function	ligase activity
C	0043436	biological_process	oxoacid metabolic process
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0004356	molecular_function	glutamine synthetase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0006538	biological_process	L-glutamate catabolic process
D	0006542	biological_process	obsolete glutamine biosynthetic process
D	0007416	biological_process	synapse assembly
D	0016874	molecular_function	ligase activity
D	0043436	biological_process	oxoacid metabolic process
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0004356	molecular_function	glutamine synthetase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0006538	biological_process	L-glutamate catabolic process
E	0006542	biological_process	obsolete glutamine biosynthetic process
E	0007416	biological_process	synapse assembly
E	0016874	molecular_function	ligase activity
E	0043436	biological_process	oxoacid metabolic process
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0004356	molecular_function	glutamine synthetase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0006538	biological_process	L-glutamate catabolic process
F	0006542	biological_process	obsolete glutamine biosynthetic process
F	0007416	biological_process	synapse assembly
F	0016874	molecular_function	ligase activity
F	0043436	biological_process	oxoacid metabolic process
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0004356	molecular_function	glutamine synthetase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0006538	biological_process	L-glutamate catabolic process
G	0006542	biological_process	obsolete glutamine biosynthetic process
G	0007416	biological_process	synapse assembly
G	0016874	molecular_function	ligase activity
G	0043436	biological_process	oxoacid metabolic process
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0004356	molecular_function	glutamine synthetase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0006538	biological_process	L-glutamate catabolic process
H	0006542	biological_process	obsolete glutamine biosynthetic process
H	0007416	biological_process	synapse assembly
H	0016874	molecular_function	ligase activity
H	0043436	biological_process	oxoacid metabolic process
I	0000166	molecular_function	nucleotide binding
I	0003824	molecular_function	catalytic activity
I	0004356	molecular_function	glutamine synthetase activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0006538	biological_process	L-glutamate catabolic process
I	0006542	biological_process	obsolete glutamine biosynthetic process
I	0007416	biological_process	synapse assembly
I	0016874	molecular_function	ligase activity
I	0043436	biological_process	oxoacid metabolic process
J	0000166	molecular_function	nucleotide binding
J	0003824	molecular_function	catalytic activity
J	0004356	molecular_function	glutamine synthetase activity
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0006538	biological_process	L-glutamate catabolic process
J	0006542	biological_process	obsolete glutamine biosynthetic process
J	0007416	biological_process	synapse assembly
J	0016874	molecular_function	ligase activity
J	0043436	biological_process	oxoacid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue ADP F 401

Chain	Residue
F	TRP136
F	ARG330
F	TYR342
F	GLU344
F	GLY138
F	GLU140
F	SER197
F	GLN211
F	GLY213
F	PRO214
F	ASN261
F	SER263

site_id	AC2
Number of Residues	13
Details	binding site for residue ADP J 401

Chain	Residue
J	TRP136
J	GLY138
J	GLU140
J	SER197
J	GLN211
J	VAL212
J	GLY213
J	PRO214
J	ASN261
J	SER263
J	ARG268
J	ARG330
J	TYR342

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	18
Details	GLNA_1 Glutamine synthetase signature 1. YDGSScyqaegs.NSDtyL

Chain	Residue	Details
A	TYR68-LEU85

site_id	PS00181
Number of Residues	17
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPMpgdw.NGAGaHtnvS

Chain	Residue	Details
A	LYS247-SER263

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	800
Details	Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1000
Details	Domain: {"description":"GS catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01331","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)