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7CPN

CRYSTAL STRUCTURE OF DODECAPRENYL DIPHOSPHATE SYNTHASE FROM THERMOBIFIDA FUSCA

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0002094molecular_functionpolyprenyltransferase activity
A0004659molecular_functionprenyltransferase activity
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
A0016094biological_processpolyprenol biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0030145molecular_functionmanganese ion binding
A0033850molecular_functionZ-farnesyl diphosphate synthase activity
A0046872molecular_functionmetal ion binding
B0000287molecular_functionmagnesium ion binding
B0002094molecular_functionpolyprenyltransferase activity
B0004659molecular_functionprenyltransferase activity
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
B0016094biological_processpolyprenol biosynthetic process
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0030145molecular_functionmanganese ion binding
B0033850molecular_functionZ-farnesyl diphosphate synthase activity
B0046872molecular_functionmetal ion binding
C0000287molecular_functionmagnesium ion binding
C0002094molecular_functionpolyprenyltransferase activity
C0004659molecular_functionprenyltransferase activity
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
C0016094biological_processpolyprenol biosynthetic process
C0016740molecular_functiontransferase activity
C0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
C0030145molecular_functionmanganese ion binding
C0033850molecular_functionZ-farnesyl diphosphate synthase activity
C0046872molecular_functionmetal ion binding
D0000287molecular_functionmagnesium ion binding
D0002094molecular_functionpolyprenyltransferase activity
D0004659molecular_functionprenyltransferase activity
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
D0016094biological_processpolyprenol biosynthetic process
D0016740molecular_functiontransferase activity
D0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
D0030145molecular_functionmanganese ion binding
D0033850molecular_functionZ-farnesyl diphosphate synthase activity
D0046872molecular_functionmetal ion binding
E0000287molecular_functionmagnesium ion binding
E0002094molecular_functionpolyprenyltransferase activity
E0004659molecular_functionprenyltransferase activity
E0005829cellular_componentcytosol
E0005886cellular_componentplasma membrane
E0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
E0016094biological_processpolyprenol biosynthetic process
E0016740molecular_functiontransferase activity
E0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
E0030145molecular_functionmanganese ion binding
E0033850molecular_functionZ-farnesyl diphosphate synthase activity
E0046872molecular_functionmetal ion binding
F0000287molecular_functionmagnesium ion binding
F0002094molecular_functionpolyprenyltransferase activity
F0004659molecular_functionprenyltransferase activity
F0005829cellular_componentcytosol
F0005886cellular_componentplasma membrane
F0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
F0016094biological_processpolyprenol biosynthetic process
F0016740molecular_functiontransferase activity
F0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
F0030145molecular_functionmanganese ion binding
F0033850molecular_functionZ-farnesyl diphosphate synthase activity
F0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue GOL A 301
ChainResidue
ATHR191
AGLU192
AALA193
AHOH476
BARG130
DSER186
DARG189
DHOH416

site_idAC2
Number of Residues8
Detailsbinding site for residue SO4 A 302
ChainResidue
AGLY45
AASN46
AGLY47
AARG57
AHIS61
AARG95
AHOH430
AASP44

site_idAC3
Number of Residues8
Detailsbinding site for residue SO4 B 301
ChainResidue
BASP44
BGLY45
BASN46
BGLY47
BARG57
BHIS61
BARG95
BHOH457

site_idAC4
Number of Residues9
Detailsbinding site for residue SO4 B 302
ChainResidue
ATYR229
AARG260
ATYR261
AGLY262
AHOH455
BARG212
BARG218
BSER220
BHOH455

site_idAC5
Number of Residues5
Detailsbinding site for residue SO4 B 303
ChainResidue
AARG184
BARG112
BARG115
BGLU141
BGLU144

site_idAC6
Number of Residues6
Detailsbinding site for residue SO4 B 304
ChainResidue
ASER186
AASN188
AARG189
BHIS119
BHIS151
BHOH446

site_idAC7
Number of Residues7
Detailsbinding site for residue SO4 C 301
ChainResidue
CGLY45
CASN46
CGLY47
CARG57
CHIS61
CARG95
CHOH412

site_idAC8
Number of Residues3
Detailsbinding site for residue SO4 C 302
ChainResidue
CARG212
CARG218
CSER220

site_idAC9
Number of Residues4
Detailsbinding site for residue SO4 D 301
ChainResidue
DASP44
DGLY45
DASN46
DGLY47

site_idAD1
Number of Residues3
Detailsbinding site for residue SO4 D 302
ChainResidue
DARG212
DARG218
DSER220

site_idAD2
Number of Residues8
Detailsbinding site for residue SO4 E 301
ChainResidue
EMET43
EASP44
EGLY45
EASN46
EGLY47
EHIS61
EARG95
EHOH406

site_idAD3
Number of Residues3
Detailsbinding site for residue SO4 E 302
ChainResidue
EARG212
EARG218
ESER220

site_idAD4
Number of Residues7
Detailsbinding site for residue SO4 F 301
ChainResidue
FASP44
FGLY45
FASN46
FGLY47
FARG57
FARG95
FHOH401

site_idAD5
Number of Residues4
Detailsbinding site for residue SO4 F 302
ChainResidue
ETYR229
FARG212
FARG218
FSER220

Functional Information from PROSITE/UniProt
site_idPS01066
Number of Residues18
DetailsUPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. DLFIRSSGeqRlSnFLLW
ChainResidueDetails
AASP208-TRP225

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsACT_SITE: ACT_SITE => ECO:0000250
ChainResidueDetails
BASP44
CASP44
DASP44
EASP44
FASP44
AASP44

site_idSWS_FT_FI2
Number of Residues6
DetailsACT_SITE: Proton acceptor => ECO:0000250
ChainResidueDetails
BASN92
CASN92
DASN92
EASN92
FASN92
AASN92

site_idSWS_FT_FI3
Number of Residues66
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BGLY45
BTRP49
BARG57
BHIS61
BSER89
BTRP93
BARG95
BARG212
BARG218
BGLU231
CASP44
CGLY45
CTRP49
CARG57
CHIS61
CSER89
CTRP93
CARG95
CARG212
CARG218
CGLU231
DASP44
DGLY45
DTRP49
DARG57
DHIS61
DSER89
DTRP93
DARG95
DARG212
DARG218
DGLU231
EASP44
EGLY45
ETRP49
EARG57
EHIS61
ESER89
ETRP93
EARG95
EARG212
EARG218
EGLU231
FASP44
FGLY45
FTRP49
FARG57
FHIS61
FSER89
FTRP93
FARG95
FARG212
FARG218
FGLU231
ATRP49
AARG57
AHIS61
ASER89
ATRP93
AARG95
AARG212
AARG218
AGLU231
BASP44
AASP44
AGLY45

221051

PDB entries from 2024-06-12

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