7CNU

Crystal structure of DLC2 in complex with BMF peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001534	cellular_component	radial spoke
A	0001673	cellular_component	male germ cell nucleus
A	0003341	biological_process	cilium movement
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005813	cellular_component	centrosome
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005868	cellular_component	cytoplasmic dynein complex
A	0005875	cellular_component	microtubule associated complex
A	0005886	cellular_component	plasma membrane
A	0005929	cellular_component	cilium
A	0005930	cellular_component	axoneme
A	0007017	biological_process	microtubule-based process
A	0014069	cellular_component	postsynaptic density
A	0015630	cellular_component	microtubule cytoskeleton
A	0016020	cellular_component	membrane
A	0030286	cellular_component	dynein complex
A	0030317	biological_process	flagellated sperm motility
A	0031475	cellular_component	myosin V complex
A	0032388	biological_process	positive regulation of intracellular transport
A	0035721	biological_process	intraciliary retrograde transport
A	0036126	cellular_component	sperm flagellum
A	0042802	molecular_function	identical protein binding
A	0044877	molecular_function	protein-containing complex binding
A	0045505	molecular_function	dynein intermediate chain binding
A	0090267	biological_process	positive regulation of mitotic cell cycle spindle assembly checkpoint
A	0097110	molecular_function	scaffold protein binding
A	0097542	cellular_component	ciliary tip
A	0097729	cellular_component	9+2 motile cilium
A	0097731	cellular_component	9+0 non-motile cilium
A	0098794	cellular_component	postsynapse
A	0098978	cellular_component	glutamatergic synapse
B	0001534	cellular_component	radial spoke
B	0001673	cellular_component	male germ cell nucleus
B	0003341	biological_process	cilium movement
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005813	cellular_component	centrosome
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005868	cellular_component	cytoplasmic dynein complex
B	0005875	cellular_component	microtubule associated complex
B	0005886	cellular_component	plasma membrane
B	0005929	cellular_component	cilium
B	0005930	cellular_component	axoneme
B	0007017	biological_process	microtubule-based process
B	0014069	cellular_component	postsynaptic density
B	0015630	cellular_component	microtubule cytoskeleton
B	0016020	cellular_component	membrane
B	0030286	cellular_component	dynein complex
B	0030317	biological_process	flagellated sperm motility
B	0031475	cellular_component	myosin V complex
B	0032388	biological_process	positive regulation of intracellular transport
B	0035721	biological_process	intraciliary retrograde transport
B	0036126	cellular_component	sperm flagellum
B	0042802	molecular_function	identical protein binding
B	0044877	molecular_function	protein-containing complex binding
B	0045505	molecular_function	dynein intermediate chain binding
B	0090267	biological_process	positive regulation of mitotic cell cycle spindle assembly checkpoint
B	0097110	molecular_function	scaffold protein binding
B	0097542	cellular_component	ciliary tip
B	0097729	cellular_component	9+2 motile cilium
B	0097731	cellular_component	9+0 non-motile cilium
B	0098794	cellular_component	postsynapse
B	0098978	cellular_component	glutamatergic synapse
E	0001534	cellular_component	radial spoke
E	0001673	cellular_component	male germ cell nucleus
E	0003341	biological_process	cilium movement
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0005868	cellular_component	cytoplasmic dynein complex
E	0005875	cellular_component	microtubule associated complex
E	0005886	cellular_component	plasma membrane
E	0005929	cellular_component	cilium
E	0005930	cellular_component	axoneme
E	0007017	biological_process	microtubule-based process
E	0014069	cellular_component	postsynaptic density
E	0015630	cellular_component	microtubule cytoskeleton
E	0016020	cellular_component	membrane
E	0030286	cellular_component	dynein complex
E	0030317	biological_process	flagellated sperm motility
E	0031475	cellular_component	myosin V complex
E	0032388	biological_process	positive regulation of intracellular transport
E	0035721	biological_process	intraciliary retrograde transport
E	0036126	cellular_component	sperm flagellum
E	0042802	molecular_function	identical protein binding
E	0044877	molecular_function	protein-containing complex binding
E	0045505	molecular_function	dynein intermediate chain binding
E	0090267	biological_process	positive regulation of mitotic cell cycle spindle assembly checkpoint
E	0097110	molecular_function	scaffold protein binding
E	0097542	cellular_component	ciliary tip
E	0097729	cellular_component	9+2 motile cilium
E	0097731	cellular_component	9+0 non-motile cilium
E	0098794	cellular_component	postsynapse
E	0098978	cellular_component	glutamatergic synapse

Functional Information from PROSITE/UniProt

site_id	PS01239
Number of Residues	15
Details	DYNEIN_LIGHT_1 Dynein light chain type 1 signature. HcIvGRnFGSyVTHE

Chain	Residue	Details
A	HIS55-GLU69

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Site: {"description":"Interaction with myosin V motor complex","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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