Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7CC3

Versatile cis-prenyltransferase MM_0014 from Methanosarcina mazei (crystal type: co-FG)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016094	biological_process	polyprenol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
A	0046872	molecular_function	metal ion binding
B	0016094	biological_process	polyprenol biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
B	0046872	molecular_function	metal ion binding
C	0016094	biological_process	polyprenol biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
C	0046872	molecular_function	metal ion binding
D	0016094	biological_process	polyprenol biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
D	0046872	molecular_function	metal ion binding
E	0016094	biological_process	polyprenol biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
E	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
E	0046872	molecular_function	metal ion binding
F	0016094	biological_process	polyprenol biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
F	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
F	0046872	molecular_function	metal ion binding
G	0016094	biological_process	polyprenol biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
G	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
G	0046872	molecular_function	metal ion binding
H	0016094	biological_process	polyprenol biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
H	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue PO4 A 301

Chain	Residue
A	ASP18
A	GLY19
A	ASN20
A	ARG21
A	ARG22
A	ARG172
A	HOH401

site_id	AC2
Number of Residues	17
Details	binding site for residue FQ0 A 302

Chain	Residue
A	ASN20
A	ILE39
A	GLY42
A	PHE59
A	PHE60
A	GLY61
A	ASN66
A	ALA80
A	SER84
A	PHE128
A	TRP195
A	FQF303
A	FV3304
A	HOH401
A	HOH437
A	PRO17
A	ASP18

site_id	AC3
Number of Residues	17
Details	binding site for residue FQF A 303

Chain	Residue
A	PRO17
A	ASP18
A	ASN20
A	TYR35
A	GLY38
A	ILE39
A	GLY42
A	LEU43
A	PHE59
A	GLY61
A	ARG69
A	ALA80
A	SER84
A	TRP195
A	FQ0302
A	FV3304
A	HOH401

site_id	AC4
Number of Residues	17
Details	binding site for residue FV3 A 304

Chain	Residue
A	PRO17
A	ASP18
A	ASN20
A	TYR35
A	GLY38
A	ILE39
A	GLY42
A	PHE59
A	GLY61
A	ASN66
A	ALA80
A	SER84
A	TRP195
A	FQ0302
A	FQF303
A	HOH401
A	HOH437

site_id	AC5
Number of Residues	10
Details	binding site for residue DPO B 301

Chain	Residue
B	ASP18
B	GLY19
B	ASN20
B	ARG21
B	ARG22
B	TYR35
B	ARG69
B	FQ0302
B	FQF303
B	FV3304

site_id	AC6
Number of Residues	15
Details	binding site for residue FQ0 B 302

Chain	Residue
B	PRO17
B	ASP18
B	ASN20
B	TYR35
B	GLY38
B	ILE39
B	GLY42
B	PHE59
B	GLY61
B	ARG69
B	PHE77
B	SER84
B	DPO301
B	FQF303
B	FV3304

site_id	AC7
Number of Residues	17
Details	binding site for residue FQF B 303

Chain	Residue
B	FV3304
B	PRO17
B	ASN20
B	TYR35
B	GLY38
B	ILE39
B	GLY42
B	PHE59
B	GLY61
B	PHE62
B	ASN66
B	ARG69
B	PHE77
B	CYS81
B	SER84
B	DPO301
B	FQ0302

site_id	AC8
Number of Residues	15
Details	binding site for residue FV3 B 304

Chain	Residue
B	ASP18
B	ASN20
B	TYR35
B	GLY38
B	ILE39
B	GLY42
B	PHE59
B	GLY61
B	ARG69
B	PHE77
B	CYS81
B	SER84
B	DPO301
B	FQ0302
B	FQF303

site_id	AC9
Number of Residues	6
Details	binding site for residue PO4 C 301

Chain	Residue
C	ASP18
C	GLY19
C	ASN20
C	ARG21
C	ARG22
C	HOH401

site_id	AD1
Number of Residues	16
Details	binding site for residue FQ0 C 302

Chain	Residue
C	PRO17
C	ASP18
C	ASN20
C	TYR35
C	ILE39
C	GLY42
C	PHE59
C	GLY61
C	ASN66
C	ARG69
C	ALA80
C	SER84
C	TRP195
C	FQF303
C	FV3304
C	HOH401

site_id	AD2
Number of Residues	15
Details	binding site for residue FQF C 303

Chain	Residue
C	PRO17
C	ASP18
C	ASN20
C	TYR35
C	GLY38
C	ILE39
C	GLY42
C	PHE59
C	GLY61
C	ASN66
C	PHE77
C	CYS81
C	SER84
C	FQ0302
C	FV3304

site_id	AD3
Number of Residues	15
Details	binding site for residue FV3 C 304

Chain	Residue
C	PRO17
C	ASP18
C	ASN20
C	GLY38
C	ILE39
C	GLY42
C	PHE59
C	GLY61
C	ARG69
C	PHE77
C	CYS81
C	SER84
C	FQ0302
C	FQF303
C	HOH401

site_id	AD4
Number of Residues	7
Details	binding site for residue PO4 D 301

Chain	Residue
D	ASP18
D	GLY19
D	ASN20
D	ARG21
D	ARG22
D	ARG172
D	HOH401

site_id	AD5
Number of Residues	18
Details	binding site for residue FQ0 D 302

Chain	Residue
D	PRO17
D	ASP18
D	ASN20
D	TYR35
D	GLY38
D	ILE39
D	GLY42
D	LEU43
D	PHE59
D	GLY61
D	ASN66
D	ARG69
D	ALA80
D	SER84
D	PHE128
D	FQF303
D	FV3304
D	HOH401

site_id	AD6
Number of Residues	16
Details	binding site for residue FQF D 303

Chain	Residue
D	PRO17
D	ASP18
D	ASN20
D	TYR35
D	ILE39
D	GLY42
D	PHE59
D	PHE60
D	GLY61
D	ASN66
D	ALA80
D	SER84
D	TRP195
D	FQ0302
D	FV3304
D	HOH401

site_id	AD7
Number of Residues	19
Details	binding site for residue FV3 D 304

Chain	Residue
D	PRO17
D	ASP18
D	ASN20
D	TYR35
D	GLY38
D	ILE39
D	GLY42
D	LEU43
D	PHE59
D	PHE60
D	GLY61
D	ASN66
D	ARG69
D	PHE77
D	CYS81
D	SER84
D	PHE128
D	FQ0302
D	FQF303

site_id	AD8
Number of Residues	11
Details	binding site for residue DPO E 301

Chain	Residue
E	ASP18
E	GLY19
E	ASN20
E	ARG21
E	ARG22
E	TYR35
E	ARG69
E	FQ0302
E	FQF303
E	FV3304
E	HOH408

site_id	AD9
Number of Residues	16
Details	binding site for residue FQ0 E 302

Chain	Residue
E	PRO17
E	ASP18
E	ASN20
E	TYR35
E	GLY38
E	ILE39
E	GLY42
E	PHE59
E	GLY61
E	ARG69
E	CYS81
E	SER84
E	PHE128
E	DPO301
E	FQF303
E	FV3304

site_id	AE1
Number of Residues	14
Details	binding site for residue FQF E 303

Chain	Residue
E	PRO17
E	ASP18
E	ASN20
E	TYR35
E	GLY38
E	GLY42
E	PHE59
E	PHE60
E	GLY61
E	PHE77
E	SER84
E	DPO301
E	FQ0302
E	FV3304

site_id	AE2
Number of Residues	17
Details	binding site for residue FV3 E 304

Chain	Residue
E	PRO17
E	ASP18
E	ASN20
E	TYR35
E	GLY38
E	ILE39
E	GLY42
E	PHE59
E	PHE60
E	GLY61
E	ASN66
E	PHE77
E	CYS81
E	SER84
E	DPO301
E	FQ0302
E	FQF303

site_id	AE3
Number of Residues	6
Details	binding site for residue PO4 F 301

Chain	Residue
F	ASP18
F	GLY19
F	ASN20
F	ARG21
F	ARG22
F	ARG172

site_id	AE4
Number of Residues	15
Details	binding site for residue FQ0 F 302

Chain	Residue
F	PRO17
F	ASP18
F	ASN20
F	TYR35
F	ILE39
F	GLY42
F	LEU43
F	PHE59
F	GLY61
F	ASN66
F	SER84
F	PHE128
F	TRP195
F	FQF303
F	FV3304

site_id	AE5
Number of Residues	15
Details	binding site for residue FQF F 303

Chain	Residue
F	ASP18
F	ASN20
F	TYR35
F	GLY38
F	ILE39
F	GLY42
F	LEU43
F	PHE59
F	GLY61
F	ASN66
F	ALA80
F	SER84
F	TRP195
F	FQ0302
F	FV3304

site_id	AE6
Number of Residues	15
Details	binding site for residue FV3 F 304

Chain	Residue
F	ASP18
F	ASN20
F	TYR35
F	GLY38
F	ILE39
F	GLY42
F	LEU43
F	PHE59
F	GLY61
F	ASN66
F	ARG69
F	SER84
F	TRP195
F	FQ0302
F	FQF303

site_id	AE7
Number of Residues	11
Details	binding site for residue DPO G 301

Chain	Residue
G	ASP18
G	GLY19
G	ASN20
G	ARG21
G	ARG22
G	TYR35
G	ARG69
G	FQ0302
G	FV3304
G	HOH421
G	HOH488

site_id	AE8
Number of Residues	17
Details	binding site for residue FQ0 G 302

Chain	Residue
G	PRO17
G	ASP18
G	ASN20
G	TYR35
G	GLY38
G	ILE39
G	GLY42
G	PHE59
G	GLY61
G	ASN66
G	ALA80
G	SER84
G	PHE128
G	TRP195
G	DPO301
G	FQF303
G	FV3304

site_id	AE9
Number of Residues	15
Details	binding site for residue FQF G 303

Chain	Residue
G	PRO17
G	ASN20
G	TYR35
G	GLY38
G	GLY42
G	LEU43
G	PHE59
G	GLY61
G	ASN66
G	ARG69
G	PHE77
G	ALA80
G	SER84
G	FQ0302
G	FV3304

site_id	AF1
Number of Residues	14
Details	binding site for residue FV3 G 304

Chain	Residue
G	ASN20
G	GLY38
G	ILE39
G	GLY42
G	PHE59
G	GLY61
G	ASN66
G	ARG69
G	ALA80
G	SER84
G	TRP195
G	DPO301
G	FQ0302
G	FQF303

site_id	AF2
Number of Residues	6
Details	binding site for residue PO4 H 301

Chain	Residue
H	ASP18
H	GLY19
H	ASN20
H	ARG21
H	ARG22
H	HOH401

site_id	AF3
Number of Residues	17
Details	binding site for residue FQ0 H 302

Chain	Residue
H	PRO17
H	ASP18
H	ASN20
H	TYR35
H	GLY38
H	ILE39
H	GLY42
H	PHE59
H	GLY61
H	ARG69
H	PHE77
H	CYS81
H	SER84
H	PHE128
H	FQF303
H	FV3304
H	HOH401

site_id	AF4
Number of Residues	15
Details	binding site for residue FQF H 303

Chain	Residue
H	ILE16
H	PRO17
H	ASN20
H	TYR35
H	GLY38
H	GLY42
H	PHE59
H	PHE60
H	GLY61
H	ASN66
H	CYS81
H	SER84
H	TRP195
H	FQ0302
H	FV3304

site_id	AF5
Number of Residues	13
Details	binding site for residue FV3 H 304

Chain	Residue
H	ASP18
H	ASN20
H	TYR35
H	ILE39
H	GLY42
H	PHE59
H	GLY61
H	ASN66
H	ARG69
H	SER84
H	FQ0302
H	FQF303
H	HOH401

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)