Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue CDP A 501 |
| Chain | Residue |
| A | GLU94 |
| A | ARG236 |
| A | TYR267 |
| A | PHE268 |
| A | LEU271 |
| A | ASN272 |
| A | ARG275 |
| A | HOH603 |
| A | HOH634 |
| A | HOH636 |
| A | HOH666 |
| A | LEU183 |
| A | GLU222 |
| A | HIS225 |
| A | ASP229 |
| A | GLY230 |
| A | ASN231 |
| A | GLY232 |
| A | ARG233 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | LEU75 |
| A | ALA76 |
| A | GLY77 |
| A | SER79 |
| A | THR80 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ARG22 |
| A | ARG26 |
| A | ARG29 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | HIS148 |
| A | HIS161 |
| A | GLN164 |
| A | VAL165 |
| A | ARG166 |
| A | PHE227 |
| A | THR228 |
| A | ASP229 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | TRP311 |
| A | MET314 |
| A | GLY364 |
| A | VAL365 |
| A | SER381 |
| A | LEU382 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | THR25 |
| A | ARG180 |
| A | HOH618 |
| A | HOH638 |
| A | HOH645 |
| B | GLY110 |
| B | ARG111 |
| B | GLY112 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 507 |
| Chain | Residue |
| A | ARG264 |
| A | GLU265 |
| A | HOH668 |
| B | LYS92 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 508 |
| Chain | Residue |
| A | ASN371 |
| A | ARG372 |
| B | ARG180 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 509 |
| Chain | Residue |
| A | SER87 |
| A | SER90 |
| A | ALA122 |
| A | LEU126 |
| A | ARG233 |
| A | ALA237 |
| site_id | AD1 |
| Number of Residues | 19 |
| Details | binding site for residue CDP B 501 |
| Chain | Residue |
| B | GLU94 |
| B | ILE172 |
| B | LEU183 |
| B | GLU222 |
| B | HIS225 |
| B | ASP229 |
| B | GLY230 |
| B | ASN231 |
| B | GLY232 |
| B | ARG233 |
| B | ARG236 |
| B | TYR267 |
| B | PHE268 |
| B | LEU271 |
| B | ASN272 |
| B | ARG275 |
| B | HOH601 |
| B | HOH657 |
| B | HOH675 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | LEU75 |
| B | GLY77 |
| B | SER79 |
| B | THR80 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| A | ARG111 |
| B | GLY24 |
| B | THR25 |
| B | ARG26 |
| B | ARG29 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | SER322 |
| B | HOH656 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | SER65 |
| A | GLU58 |
| A | MET61 |
| A | SER62 |
| A | SER65 |
| B | GLU58 |
| B | MET61 |
| B | SER62 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| A | ARG396 |
| B | HIS263 |
| B | ARG264 |
| B | GLU265 |
| B | ARG266 |
| B | ACT509 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 507 |
| Chain | Residue |
| A | ARG180 |
| B | THR370 |
| B | ASN371 |
| B | LYS373 |
| B | HOH626 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 508 |
| Chain | Residue |
| A | GLY110 |
| A | ARG111 |
| A | GLY112 |
| B | THR25 |
| B | ALA27 |
| B | ARG180 |
| B | HOH635 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 509 |
| Chain | Residue |
| A | LYS92 |
| B | VAL261 |
| B | ALA262 |
| B | ARG264 |
| B | GLU265 |
| B | EDO506 |
| B | HOH617 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 510 |
| Chain | Residue |
| B | SER90 |
| B | ALA122 |
| B | LEU126 |
| B | ARG233 |
| B | ALA237 |
