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7C6Q

Novel natural PPARalpha agonist with a unique binding mode

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue SAU A 501
ChainResidue
ALEU247
APHE421
AHOH627
AGLU251
ALEU254
AVAL255
AARG271
ACYS275
ACYS278
AALA333
ATYR334

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER698
ATYR314
ATYR464

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Essential for heterodimerization with RXRA
ChainResidueDetails
ALEU433

227111

PDB entries from 2024-11-06

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