7C4C

The crystal structure of Trypanosoma brucei RNase D : GMP complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000175	molecular_function	3'-5'-RNA exonuclease activity
A	0003676	molecular_function	nucleic acid binding
A	0005739	cellular_component	mitochondrion
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0008270	molecular_function	zinc ion binding
A	0008408	molecular_function	3'-5' exonuclease activity
A	0020023	cellular_component	kinetoplast
A	0034587	biological_process	piRNA processing
A	0046872	molecular_function	metal ion binding
A	1990923	cellular_component	PET complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 401

Chain	Residue
A	CYS320
A	CYS323
A	HIS328
A	CYS333

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 402

Chain	Residue
A	CYS297
A	CYS300
A	HIS305
A	CYS310

---

site_id	AC3
Number of Residues	3
Details	binding site for residue ZN A 403

Chain	Residue
A	LYS65
A	ASP125
A	HIS61

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 404

Chain	Residue
A	GLU197
A	HIS233
A	HIS375
A	HOH539

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN A 405

Chain	Residue
A	CYS362
A	CYS365
A	HIS369
A	CYS374

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN A 406

Chain	Residue
A	CYS343
A	CYS346
A	HIS351
A	CYS356

---

site_id	AC7
Number of Residues	5
Details	binding site for residue MN A 407

Chain	Residue
A	ASP80
A	GLU82
A	ASP230
A	5GP413
A	HOH521

---

site_id	AC8
Number of Residues	5
Details	binding site for residue MN A 408

Chain	Residue
A	ASP80
A	ASP145
A	5GP413
A	HOH501
A	HOH503

---

site_id	AC9
Number of Residues	3
Details	binding site for residue MN A 409

Chain	Residue
A	GLU325
A	LYS335
A	5GP414

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MN A 410

Chain	Residue
A	GLN203
A	5GP413

---

site_id	AD2
Number of Residues	3
Details	binding site for residue MN A 411

Chain	Residue
A	ALA330
A	LYS336
A	HIS337

---

site_id	AD3
Number of Residues	1
Details	binding site for residue MN A 412

Chain	Residue
A	5GP416

---

site_id	AD4
Number of Residues	13
Details	binding site for residue 5GP A 413

Chain	Residue
A	ASP80
A	ILE81
A	GLU82
A	ALA83
A	LEU93
A	MSE206
A	TRP214
A	ASP230
A	MN407
A	MN408
A	MN410
A	HOH512
A	HOH521

---

site_id	AD5
Number of Residues	6
Details	binding site for residue 5GP A 414

Chain	Residue
A	GLU325
A	HIS328
A	ASN332
A	CYS333
A	PHE334
A	MN409

---

site_id	AD6
Number of Residues	3
Details	binding site for residue 5GP A 415

Chain	Residue
A	ASP141
A	ARG143
A	GLN164

---

site_id	AD7
Number of Residues	5
Details	binding site for residue 5GP A 416

Chain	Residue
A	HIS305
A	GLU309
A	CYS310
A	PHE311
A	MN412

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