7C45

The crystal structure of Trypanosoma brucei RNase D complex with RNA U12

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0008270	molecular_function	zinc ion binding
A	0008408	molecular_function	3'-5' exonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 401

Chain	Residue
A	CYS297
A	CYS300
A	HIS305
A	CYS310

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 402

Chain	Residue
A	CYS320
A	CYS323
A	HIS328
A	CYS333

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site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 403

Chain	Residue
A	GLU82
A	ASP230
A	HOH606
A	HOH666
D	U12
A	ASP80

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site_id	AC4
Number of Residues	6
Details	binding site for residue CA D 101

Chain	Residue
A	ASP80
A	HOH513
A	HOH515
A	HOH619
D	U11
D	U12

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