7C3F

Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin m2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
B	0015979	biological_process	photosynthesis
C	0015035	molecular_function	protein-disulfide reductase activity
D	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
E	0015979	biological_process	photosynthesis
F	0015035	molecular_function	protein-disulfide reductase activity
G	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
H	0015979	biological_process	photosynthesis
I	0015035	molecular_function	protein-disulfide reductase activity
J	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
K	0015979	biological_process	photosynthesis
L	0015035	molecular_function	protein-disulfide reductase activity
M	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
N	0015979	biological_process	photosynthesis
O	0015035	molecular_function	protein-disulfide reductase activity
P	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
Q	0015979	biological_process	photosynthesis
R	0015035	molecular_function	protein-disulfide reductase activity
S	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
T	0015979	biological_process	photosynthesis
U	0015035	molecular_function	protein-disulfide reductase activity
V	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
W	0015035	molecular_function	protein-disulfide reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SF4 A 201

Chain	Residue
A	CYS54
A	CYS73
A	CYS75
A	MET78
A	CYS84
A	HIS85
A	CYS86

---

site_id	AC2
Number of Residues	5
Details	binding site for residue NA A 202

Chain	Residue
A	THR35
A	MET87
A	LEU88
A	PHE28
A	CYS29

---

site_id	AC3
Number of Residues	4
Details	binding site for residue NA C 201

Chain	Residue
C	SER16
C	THR17
C	SER20
D	MET115

---

site_id	AC4
Number of Residues	7
Details	binding site for residue SF4 D 201

Chain	Residue
D	CYS54
D	CYS73
D	CYS75
D	MET78
D	CYS84
D	HIS85
D	CYS86

---

site_id	AC5
Number of Residues	5
Details	binding site for residue NA D 202

Chain	Residue
D	PHE28
D	CYS29
D	THR35
D	MET87
D	LEU88

---

site_id	AC6
Number of Residues	5
Details	binding site for residue NA E 201

Chain	Residue
E	VAL46
E	TYR47
E	HIS48
E	VAL49
E	VAL52

---

site_id	AC7
Number of Residues	7
Details	binding site for residue SF4 G 201

Chain	Residue
G	CYS54
G	CYS73
G	CYS75
G	MET78
G	CYS84
G	HIS85
G	CYS86

---

site_id	AC8
Number of Residues	5
Details	binding site for residue NA G 202

Chain	Residue
G	PHE28
G	CYS29
G	THR35
G	MET87
G	LEU88

---

site_id	AC9
Number of Residues	7
Details	binding site for residue SF4 J 201

Chain	Residue
J	CYS54
J	CYS73
J	CYS75
J	MET78
J	CYS84
J	HIS85
J	CYS86

---

site_id	AD1
Number of Residues	5
Details	binding site for residue NA J 202

Chain	Residue
J	PHE28
J	CYS29
J	THR35
J	MET87
J	LEU88

---

site_id	AD2
Number of Residues	6
Details	binding site for residue NA L 201

Chain	Residue
L	ASP15
L	SER16
L	TRP18
L	ASP19
O	HOH310
O	HOH347

---

site_id	AD3
Number of Residues	7
Details	binding site for residue SF4 M 201

Chain	Residue
M	CYS54
M	CYS73
M	CYS75
M	MET78
M	CYS84
M	HIS85
M	CYS86

---

site_id	AD4
Number of Residues	5
Details	binding site for residue NA M 202

Chain	Residue
M	PHE28
M	CYS29
M	THR35
M	MET87
M	LEU88

---

site_id	AD5
Number of Residues	3
Details	binding site for residue NA O 201

Chain	Residue
M	HIS58
O	THR66
O	ASP67

---

site_id	AD6
Number of Residues	8
Details	binding site for residue SF4 P 201

Chain	Residue
P	CYS54
P	CYS73
P	CYS75
P	MET78
P	CYS84
P	HIS85
P	CYS86
P	HOH312

---

site_id	AD7
Number of Residues	4
Details	binding site for residue NA P 202

Chain	Residue
P	ARG57
P	HIS58
Q	SER77
R	ARG79

---

site_id	AD8
Number of Residues	7
Details	binding site for residue SF4 S 201

Chain	Residue
S	CYS54
S	CYS73
S	CYS75
S	MET78
S	CYS84
S	HIS85
S	CYS86

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"Q55389","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33015914","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7BZK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7C2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7C3F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Site: {"description":"Increases the nucleophilicity of the active site Cys","evidences":[{"source":"UniProtKB","id":"Q55389","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Site: {"description":"Deprotonates C-terminal active site Cys","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	16
Details	Site: {"description":"Contributes to redox potential value","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---