7C3F

Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin m2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
B	0015979	biological_process	photosynthesis
C	0015035	molecular_function	protein-disulfide reductase activity
D	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
E	0015979	biological_process	photosynthesis
F	0015035	molecular_function	protein-disulfide reductase activity
G	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
H	0015979	biological_process	photosynthesis
I	0015035	molecular_function	protein-disulfide reductase activity
J	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
K	0015979	biological_process	photosynthesis
L	0015035	molecular_function	protein-disulfide reductase activity
M	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
N	0015979	biological_process	photosynthesis
O	0015035	molecular_function	protein-disulfide reductase activity
P	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
Q	0015979	biological_process	photosynthesis
R	0015035	molecular_function	protein-disulfide reductase activity
S	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
T	0015979	biological_process	photosynthesis
U	0015035	molecular_function	protein-disulfide reductase activity
V	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
W	0015035	molecular_function	protein-disulfide reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SF4 A 201

Chain	Residue
A	CYS54
A	CYS73
A	CYS75
A	MET78
A	CYS84
A	HIS85
A	CYS86

---

site_id	AC2
Number of Residues	5
Details	binding site for residue NA A 202

Chain	Residue
A	THR35
A	MET87
A	LEU88
A	PHE28
A	CYS29

---

site_id	AC3
Number of Residues	4
Details	binding site for residue NA C 201

Chain	Residue
C	SER16
C	THR17
C	SER20
D	MET115

---

site_id	AC4
Number of Residues	7
Details	binding site for residue SF4 D 201

Chain	Residue
D	CYS54
D	CYS73
D	CYS75
D	MET78
D	CYS84
D	HIS85
D	CYS86

---

site_id	AC5
Number of Residues	5
Details	binding site for residue NA D 202

Chain	Residue
D	PHE28
D	CYS29
D	THR35
D	MET87
D	LEU88

---

site_id	AC6
Number of Residues	5
Details	binding site for residue NA E 201

Chain	Residue
E	VAL46
E	TYR47
E	HIS48
E	VAL49
E	VAL52

---

site_id	AC7
Number of Residues	7
Details	binding site for residue SF4 G 201

Chain	Residue
G	CYS54
G	CYS73
G	CYS75
G	MET78
G	CYS84
G	HIS85
G	CYS86

---

site_id	AC8
Number of Residues	5
Details	binding site for residue NA G 202

Chain	Residue
G	PHE28
G	CYS29
G	THR35
G	MET87
G	LEU88

---

site_id	AC9
Number of Residues	7
Details	binding site for residue SF4 J 201

Chain	Residue
J	CYS54
J	CYS73
J	CYS75
J	MET78
J	CYS84
J	HIS85
J	CYS86

---

site_id	AD1
Number of Residues	5
Details	binding site for residue NA J 202

Chain	Residue
J	PHE28
J	CYS29
J	THR35
J	MET87
J	LEU88

---

site_id	AD2
Number of Residues	6
Details	binding site for residue NA L 201

Chain	Residue
L	ASP15
L	SER16
L	TRP18
L	ASP19
O	HOH310
O	HOH347

---

site_id	AD3
Number of Residues	7
Details	binding site for residue SF4 M 201

Chain	Residue
M	CYS54
M	CYS73
M	CYS75
M	MET78
M	CYS84
M	HIS85
M	CYS86

---

site_id	AD4
Number of Residues	5
Details	binding site for residue NA M 202

Chain	Residue
M	PHE28
M	CYS29
M	THR35
M	MET87
M	LEU88

---

site_id	AD5
Number of Residues	3
Details	binding site for residue NA O 201

Chain	Residue
M	HIS58
O	THR66
O	ASP67

---

site_id	AD6
Number of Residues	8
Details	binding site for residue SF4 P 201

Chain	Residue
P	CYS54
P	CYS73
P	CYS75
P	MET78
P	CYS84
P	HIS85
P	CYS86
P	HOH312

---

site_id	AD7
Number of Residues	4
Details	binding site for residue NA P 202

Chain	Residue
P	ARG57
P	HIS58
Q	SER77
R	ARG79

---

site_id	AD8
Number of Residues	7
Details	binding site for residue SF4 S 201

Chain	Residue
S	CYS54
S	CYS73
S	CYS75
S	MET78
S	CYS84
S	HIS85
S	CYS86

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	ACT_SITE: Nucleophile => ECO:0000250

Chain	Residue	Details
C	CYS38
O	SER41
R	CYS38
R	SER41
U	CYS38
U	SER41
W	CYS38
W	SER41
C	SER41
F	CYS38
F	SER41
I	CYS38
I	SER41
L	CYS38
L	SER41
O	CYS38

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	SITE: Deprotonates C-terminal active site Cys => ECO:0000250

Chain	Residue	Details
C	ASP32
G	CYS73
G	CYS75
G	CYS84
J	CYS54
J	CYS73
J	CYS75
J	CYS84
M	CYS54
M	CYS73
M	CYS75
F	ASP32
M	CYS84
P	CYS54
P	CYS73
P	CYS75
P	CYS84
S	CYS54
S	CYS73
S	CYS75
S	CYS84
V	CYS54
I	ASP32
V	CYS73
V	CYS75
V	CYS84
L	ASP32
O	ASP32
R	ASP32
U	ASP32
W	ASP32
G	CYS54

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	SITE: Contributes to redox potential value => ECO:0000250

Chain	Residue	Details
C	GLY39
O	PRO40
R	GLY39
R	PRO40
U	GLY39
U	PRO40
W	GLY39
W	PRO40
C	PRO40
F	GLY39
F	PRO40
I	GLY39
I	PRO40
L	GLY39
L	PRO40
O	GLY39

---