Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | ASN48 |
| A | TRP64 |
| A | TRP68 |
| A | ARG303 |
| A | GLU315 |
| A | HOH518 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ILE230 |
| A | SER266 |
| A | LYS273 |
| A | HOH580 |
| C | HIS270 |
| A | GLN227 |
| A | PHE228 |
| A | VAL229 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | TRP90 |
| A | GLU109 |
| A | GLY124 |
| A | ALA125 |
| A | LEU126 |
| A | LEU149 |
| A | PHE165 |
| A | TRP171 |
| A | HOH569 |
| A | HOH658 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | GLU215 |
| A | GLN227 |
| A | PHE228 |
| A | ASN268 |
| A | TRP272 |
| A | HOH551 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | SER12 |
| A | HIS14 |
| A | GLU24 |
| A | ASP25 |
| A | ILE26 |
| A | GLN309 |
| A | SO4411 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | ARG295 |
| A | ASP296 |
| A | ASP297 |
| A | TYR320 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | TRP47 |
| A | ARG63 |
| A | THR114 |
| A | HOH585 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| A | TYR40 |
| A | THR242 |
| A | THR291 |
| A | SER292 |
| A | HOH542 |
| A | HOH543 |
| A | HOH546 |
| A | HOH582 |
| A | HOH593 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 409 |
| Chain | Residue |
| A | ALA38 |
| A | SER39 |
| A | THR86 |
| A | ALA87 |
| A | SER289 |
| A | HOH524 |
| A | HOH593 |
| A | HOH600 |
| A | HOH631 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 410 |
| Chain | Residue |
| A | TYR40 |
| A | PRO43 |
| A | TRP195 |
| A | HOH504 |
| A | HOH572 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 411 |
| Chain | Residue |
| A | LYS326 |
| A | SER329 |
| A | GOL405 |
| A | HOH621 |
| A | HOH694 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 412 |
| Chain | Residue |
| A | ARG295 |
| A | ARG319 |
| A | HOH685 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | ASN48 |
| B | TRP64 |
| B | ARG303 |
| B | GLU315 |
| B | HOH502 |
| B | HOH722 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | GLN227 |
| B | PHE228 |
| B | VAL229 |
| B | ILE230 |
| B | SER266 |
| B | TRP272 |
| B | LYS273 |
| B | HOH687 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | GLU109 |
| B | ALA125 |
| B | LEU126 |
| B | LEU149 |
| B | TRP171 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| B | GLU215 |
| B | GLN227 |
| B | PHE228 |
| B | TRP272 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| B | GLU162 |
| B | ILE202 |
| B | TRP218 |
| B | TRP223 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 406 |
| Chain | Residue |
| B | THR242 |
| B | THR291 |
| B | SER292 |
| B | HOH506 |
| B | HOH515 |
| B | HOH535 |
| B | HOH561 |
| B | HOH606 |
| B | HOH705 |
| site_id | AE1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 407 |
| Chain | Residue |
| B | ALA38 |
| B | SER39 |
| B | THR86 |
| B | ALA87 |
| B | SER289 |
| B | HOH516 |
| B | HOH558 |
| B | HOH562 |
| B | HOH606 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 408 |
| Chain | Residue |
| A | HOH559 |
| B | ARG34 |
| B | HOH549 |
| B | HOH632 |
| B | HOH670 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 409 |
| Chain | Residue |
| B | LYS326 |
| B | HIS328 |
| B | SER329 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 401 |
| Chain | Residue |
| C | ASN48 |
| C | ARG303 |
| C | GLU315 |
| C | HOH543 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| C | GLN227 |
| C | PHE228 |
| C | VAL229 |
| C | ILE230 |
| C | SER266 |
| C | LYS273 |
| C | HOH654 |
| C | HOH693 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | TRP90 |
| C | GLU109 |
| C | GLY124 |
| C | ALA125 |
| C | LEU149 |
| C | TRP171 |
| C | HOH503 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 404 |
| Chain | Residue |
| C | GLU215 |
| C | VAL217 |
| C | GLN227 |
| C | PHE228 |
| C | TRP272 |
| C | HOH709 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 405 |
| Chain | Residue |
| C | TYR40 |
| C | THR242 |
| C | VAL243 |
| C | THR291 |
| C | SER292 |
| C | HOH501 |
| C | HOH524 |
| C | HOH697 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 406 |
| Chain | Residue |
| C | SER12 |
| C | HIS14 |
| C | GLU24 |
| C | ASP25 |
| C | ILE26 |
| C | GLN309 |
| C | HOH564 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 407 |
| Chain | Residue |
| C | PHE144 |
| C | TYR152 |
| C | GLU162 |
| C | THR164 |
| C | ILE202 |
| C | TRP218 |
| C | HOH723 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 408 |
| Chain | Residue |
| C | ALA38 |
| C | SER39 |
| C | THR86 |
| C | ALA87 |
| C | SER289 |
| C | HOH524 |
| C | HOH606 |
| C | HOH626 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 409 |
| Chain | Residue |
| C | LYS326 |
| C | HIS328 |
| C | SER329 |
| C | HOH526 |
| C | HOH564 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 401 |
| Chain | Residue |
| D | ASN48 |
| D | TRP64 |
| D | ARG303 |
| D | GLU315 |
| D | HOH511 |
| site_id | AF5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 402 |
| Chain | Residue |
| D | GLN227 |
| D | PHE228 |
| D | VAL229 |
| D | ILE230 |
| D | SER266 |
| D | LYS273 |
| D | PRO275 |
| D | HOH523 |
| D | HOH545 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 403 |
| Chain | Residue |
| D | TRP90 |
| D | GLU109 |
| D | GLY124 |
| D | ALA125 |
| D | TRP171 |
| D | HOH700 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 404 |
| Chain | Residue |
| D | GLU215 |
| D | GLN227 |
| D | PHE228 |
| D | TRP272 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL D 405 |
| Chain | Residue |
| D | GLU162 |
| D | TRP218 |
| D | TRP223 |
| site_id | AF9 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 D 406 |
| Chain | Residue |
| D | TYR40 |
| D | LYS194 |
| D | THR242 |
| D | THR291 |
| D | SER292 |
| D | HOH532 |
| D | HOH538 |
| D | HOH547 |
| D | HOH571 |
| D | HOH632 |
| D | HOH640 |
| site_id | AG1 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 D 407 |
| Chain | Residue |
| D | ALA38 |
| D | SER39 |
| D | THR86 |
| D | ALA87 |
| D | SER289 |
| D | HOH520 |
| D | HOH522 |
| D | HOH533 |
| D | HOH576 |
| D | HOH632 |
| D | HOH697 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 408 |
| Chain | Residue |
| D | LYS326 |
| D | SER329 |
| D | HOH660 |
| site_id | AG3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 409 |
| Chain | Residue |
| C | ARG34 |
| C | HOH508 |
| D | ARG34 |
| D | LYS285 |
| D | HOH501 |
| D | HOH574 |
| D | HOH616 |
