7BZJ
The Discovery of Benzhydrol-Oxaborole Hybrid Derivatives as Leucyl-tRNA Synthetase Inhibitors
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue FGX A 501 |
| Chain | Residue |
| A | PHE246 |
| A | MET338 |
| A | HIS343 |
| A | ASP344 |
| A | THR373 |
| A | LYS389 |
| A | HOH606 |
| A | HOH617 |
| A | HOH643 |
| A | HOH660 |
| A | HOH686 |
| A | THR247 |
| A | HOH690 |
| A | HOH696 |
| A | HOH701 |
| A | THR248 |
| A | ARG249 |
| A | TYR327 |
| A | VAL328 |
| A | LEU329 |
| A | TYR332 |
| A | VAL337 |
