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7BYM

Cryo-EM structure of human KCNQ4 with retigabine

Functional Information from GO Data
ChainGOidnamespacecontents
A0005216molecular_functionmonoatomic ion channel activity
A0005249molecular_functionvoltage-gated potassium channel activity
A0005267molecular_functionpotassium channel activity
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0006091biological_processgeneration of precursor metabolites and energy
A0006811biological_processmonoatomic ion transport
A0006813biological_processpotassium ion transport
A0007605biological_processsensory perception of sound
A0008076cellular_componentvoltage-gated potassium channel complex
A0008218biological_processbioluminescence
A0009925cellular_componentbasal plasma membrane
A0016020cellular_componentmembrane
A0034220biological_processmonoatomic ion transmembrane transport
A0034702cellular_componentmonoatomic ion channel complex
A0042472biological_processinner ear morphogenesis
A0055085biological_processtransmembrane transport
A0071805biological_processpotassium ion transmembrane transport
B0000086biological_processG2/M transition of mitotic cell cycle
B0000922cellular_componentspindle pole
B0001975biological_processresponse to amphetamine
B0002027biological_processregulation of heart rate
B0005246molecular_functioncalcium channel regulator activity
B0005509molecular_functioncalcium ion binding
B0005513biological_processdetection of calcium ion
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005813cellular_componentcentrosome
B0005819cellular_componentspindle
B0005856cellular_componentcytoskeleton
B0005876cellular_componentspindle microtubule
B0005886cellular_componentplasma membrane
B0007186biological_processG protein-coupled receptor signaling pathway
B0008076cellular_componentvoltage-gated potassium channel complex
B0008179molecular_functionadenylate cyclase binding
B0010856molecular_functionadenylate cyclase activator activity
B0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B0016020cellular_componentmembrane
B0019901molecular_functionprotein kinase binding
B0019904molecular_functionprotein domain specific binding
B0021762biological_processsubstantia nigra development
B0030017cellular_componentsarcomere
B0030235molecular_functionnitric-oxide synthase regulator activity
B0030426cellular_componentgrowth cone
B0030672cellular_componentsynaptic vesicle membrane
B0031432molecular_functiontitin binding
B0031800molecular_functiontype 3 metabotropic glutamate receptor binding
B0031966cellular_componentmitochondrial membrane
B0031982cellular_componentvesicle
B0032465biological_processregulation of cytokinesis
B0032991cellular_componentprotein-containing complex
B0034704cellular_componentcalcium channel complex
B0043209cellular_componentmyelin sheath
B0043539molecular_functionprotein serine/threonine kinase activator activity
B0043548molecular_functionphosphatidylinositol 3-kinase binding
B0044305cellular_componentcalyx of Held
B0044325molecular_functiontransmembrane transporter binding
B0046872molecular_functionmetal ion binding
B0048306molecular_functioncalcium-dependent protein binding
B0050848biological_processregulation of calcium-mediated signaling
B0050998molecular_functionnitric-oxide synthase binding
B0051412biological_processresponse to corticosterone
B0051592biological_processresponse to calcium ion
B0055117biological_processregulation of cardiac muscle contraction
B0060291biological_processlong-term synaptic potentiation
B0072542molecular_functionprotein phosphatase activator activity
B0090150biological_processestablishment of protein localization to membrane
B0090151biological_processestablishment of protein localization to mitochondrial membrane
B0097225cellular_componentsperm midpiece
B0097720biological_processcalcineurin-mediated signaling
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098901biological_processregulation of cardiac muscle cell action potential
B0099523cellular_componentpresynaptic cytosol
B0099524cellular_componentpostsynaptic cytosol
B0140238biological_processpresynaptic endocytosis
B0141110molecular_functiontransporter inhibitor activity
B1900242biological_processregulation of synaptic vesicle endocytosis
B1901842biological_processnegative regulation of high voltage-gated calcium channel activity
B1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
B1902494cellular_componentcatalytic complex
B1905913biological_processnegative regulation of calcium ion export across plasma membrane
B2000300biological_processregulation of synaptic vesicle exocytosis
C0005216molecular_functionmonoatomic ion channel activity
C0005249molecular_functionvoltage-gated potassium channel activity
C0005267molecular_functionpotassium channel activity
C0005515molecular_functionprotein binding
C0005886cellular_componentplasma membrane
C0006091biological_processgeneration of precursor metabolites and energy
C0006811biological_processmonoatomic ion transport
C0006813biological_processpotassium ion transport
C0007605biological_processsensory perception of sound
C0008076cellular_componentvoltage-gated potassium channel complex
C0008218biological_processbioluminescence
C0009925cellular_componentbasal plasma membrane
C0016020cellular_componentmembrane
C0034220biological_processmonoatomic ion transmembrane transport
C0034702cellular_componentmonoatomic ion channel complex
C0042472biological_processinner ear morphogenesis
C0055085biological_processtransmembrane transport
C0071805biological_processpotassium ion transmembrane transport
D0000086biological_processG2/M transition of mitotic cell cycle
D0000922cellular_componentspindle pole
D0001975biological_processresponse to amphetamine
D0002027biological_processregulation of heart rate
D0005246molecular_functioncalcium channel regulator activity
D0005509molecular_functioncalcium ion binding
D0005513biological_processdetection of calcium ion
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005813cellular_componentcentrosome
D0005819cellular_componentspindle
D0005856cellular_componentcytoskeleton
D0005876cellular_componentspindle microtubule
D0005886cellular_componentplasma membrane
D0007186biological_processG protein-coupled receptor signaling pathway
D0008076cellular_componentvoltage-gated potassium channel complex
D0008179molecular_functionadenylate cyclase binding
D0010856molecular_functionadenylate cyclase activator activity
D0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
D0016020cellular_componentmembrane
D0019901molecular_functionprotein kinase binding
D0019904molecular_functionprotein domain specific binding
D0021762biological_processsubstantia nigra development
D0030017cellular_componentsarcomere
D0030235molecular_functionnitric-oxide synthase regulator activity
D0030426cellular_componentgrowth cone
D0030672cellular_componentsynaptic vesicle membrane
D0031432molecular_functiontitin binding
D0031800molecular_functiontype 3 metabotropic glutamate receptor binding
D0031966cellular_componentmitochondrial membrane
D0031982cellular_componentvesicle
D0032465biological_processregulation of cytokinesis
D0032991cellular_componentprotein-containing complex
D0034704cellular_componentcalcium channel complex
D0043209cellular_componentmyelin sheath
D0043539molecular_functionprotein serine/threonine kinase activator activity
D0043548molecular_functionphosphatidylinositol 3-kinase binding
D0044305cellular_componentcalyx of Held
D0044325molecular_functiontransmembrane transporter binding
D0046872molecular_functionmetal ion binding
D0048306molecular_functioncalcium-dependent protein binding
D0050848biological_processregulation of calcium-mediated signaling
D0050998molecular_functionnitric-oxide synthase binding
D0051412biological_processresponse to corticosterone
D0051592biological_processresponse to calcium ion
D0055117biological_processregulation of cardiac muscle contraction
D0060291biological_processlong-term synaptic potentiation
D0072542molecular_functionprotein phosphatase activator activity
D0090150biological_processestablishment of protein localization to membrane
D0090151biological_processestablishment of protein localization to mitochondrial membrane
D0097225cellular_componentsperm midpiece
D0097720biological_processcalcineurin-mediated signaling
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098901biological_processregulation of cardiac muscle cell action potential
D0099523cellular_componentpresynaptic cytosol
D0099524cellular_componentpostsynaptic cytosol
D0140238biological_processpresynaptic endocytosis
D0141110molecular_functiontransporter inhibitor activity
D1900242biological_processregulation of synaptic vesicle endocytosis
D1901842biological_processnegative regulation of high voltage-gated calcium channel activity
D1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
D1902494cellular_componentcatalytic complex
D1905913biological_processnegative regulation of calcium ion export across plasma membrane
D2000300biological_processregulation of synaptic vesicle exocytosis
E0005216molecular_functionmonoatomic ion channel activity
E0005249molecular_functionvoltage-gated potassium channel activity
E0005267molecular_functionpotassium channel activity
E0005515molecular_functionprotein binding
E0005886cellular_componentplasma membrane
E0006091biological_processgeneration of precursor metabolites and energy
E0006811biological_processmonoatomic ion transport
E0006813biological_processpotassium ion transport
E0007605biological_processsensory perception of sound
E0008076cellular_componentvoltage-gated potassium channel complex
E0008218biological_processbioluminescence
E0009925cellular_componentbasal plasma membrane
E0016020cellular_componentmembrane
E0034220biological_processmonoatomic ion transmembrane transport
E0034702cellular_componentmonoatomic ion channel complex
E0042472biological_processinner ear morphogenesis
E0055085biological_processtransmembrane transport
E0071805biological_processpotassium ion transmembrane transport
F0000086biological_processG2/M transition of mitotic cell cycle
F0000922cellular_componentspindle pole
F0001975biological_processresponse to amphetamine
F0002027biological_processregulation of heart rate
F0005246molecular_functioncalcium channel regulator activity
F0005509molecular_functioncalcium ion binding
F0005513biological_processdetection of calcium ion
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005813cellular_componentcentrosome
F0005819cellular_componentspindle
F0005856cellular_componentcytoskeleton
F0005876cellular_componentspindle microtubule
F0005886cellular_componentplasma membrane
F0007186biological_processG protein-coupled receptor signaling pathway
F0008076cellular_componentvoltage-gated potassium channel complex
F0008179molecular_functionadenylate cyclase binding
F0010856molecular_functionadenylate cyclase activator activity
F0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
F0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
F0016020cellular_componentmembrane
F0019901molecular_functionprotein kinase binding
F0019904molecular_functionprotein domain specific binding
F0021762biological_processsubstantia nigra development
F0030017cellular_componentsarcomere
F0030235molecular_functionnitric-oxide synthase regulator activity
F0030426cellular_componentgrowth cone
F0030672cellular_componentsynaptic vesicle membrane
F0031432molecular_functiontitin binding
F0031800molecular_functiontype 3 metabotropic glutamate receptor binding
F0031966cellular_componentmitochondrial membrane
F0031982cellular_componentvesicle
F0032465biological_processregulation of cytokinesis
F0032991cellular_componentprotein-containing complex
F0034704cellular_componentcalcium channel complex
F0043209cellular_componentmyelin sheath
F0043539molecular_functionprotein serine/threonine kinase activator activity
F0043548molecular_functionphosphatidylinositol 3-kinase binding
F0044305cellular_componentcalyx of Held
F0044325molecular_functiontransmembrane transporter binding
F0046872molecular_functionmetal ion binding
F0048306molecular_functioncalcium-dependent protein binding
F0050848biological_processregulation of calcium-mediated signaling
F0050998molecular_functionnitric-oxide synthase binding
F0051412biological_processresponse to corticosterone
F0051592biological_processresponse to calcium ion
F0055117biological_processregulation of cardiac muscle contraction
F0060291biological_processlong-term synaptic potentiation
F0072542molecular_functionprotein phosphatase activator activity
F0090150biological_processestablishment of protein localization to membrane
F0090151biological_processestablishment of protein localization to mitochondrial membrane
F0097225cellular_componentsperm midpiece
F0097720biological_processcalcineurin-mediated signaling
F0098685cellular_componentSchaffer collateral - CA1 synapse
F0098901biological_processregulation of cardiac muscle cell action potential
F0099523cellular_componentpresynaptic cytosol
F0099524cellular_componentpostsynaptic cytosol
F0140238biological_processpresynaptic endocytosis
F0141110molecular_functiontransporter inhibitor activity
F1900242biological_processregulation of synaptic vesicle endocytosis
F1901842biological_processnegative regulation of high voltage-gated calcium channel activity
F1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
F1902494cellular_componentcatalytic complex
F1905913biological_processnegative regulation of calcium ion export across plasma membrane
F2000300biological_processregulation of synaptic vesicle exocytosis
G0005216molecular_functionmonoatomic ion channel activity
G0005249molecular_functionvoltage-gated potassium channel activity
G0005267molecular_functionpotassium channel activity
G0005515molecular_functionprotein binding
G0005886cellular_componentplasma membrane
G0006091biological_processgeneration of precursor metabolites and energy
G0006811biological_processmonoatomic ion transport
G0006813biological_processpotassium ion transport
G0007605biological_processsensory perception of sound
G0008076cellular_componentvoltage-gated potassium channel complex
G0008218biological_processbioluminescence
G0009925cellular_componentbasal plasma membrane
G0016020cellular_componentmembrane
G0034220biological_processmonoatomic ion transmembrane transport
G0034702cellular_componentmonoatomic ion channel complex
G0042472biological_processinner ear morphogenesis
G0055085biological_processtransmembrane transport
G0071805biological_processpotassium ion transmembrane transport
H0000086biological_processG2/M transition of mitotic cell cycle
H0000922cellular_componentspindle pole
H0001975biological_processresponse to amphetamine
H0002027biological_processregulation of heart rate
H0005246molecular_functioncalcium channel regulator activity
H0005509molecular_functioncalcium ion binding
H0005513biological_processdetection of calcium ion
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005813cellular_componentcentrosome
H0005819cellular_componentspindle
H0005856cellular_componentcytoskeleton
H0005876cellular_componentspindle microtubule
H0005886cellular_componentplasma membrane
H0007186biological_processG protein-coupled receptor signaling pathway
H0008076cellular_componentvoltage-gated potassium channel complex
H0008179molecular_functionadenylate cyclase binding
H0010856molecular_functionadenylate cyclase activator activity
H0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
H0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
H0016020cellular_componentmembrane
H0019901molecular_functionprotein kinase binding
H0019904molecular_functionprotein domain specific binding
H0021762biological_processsubstantia nigra development
H0030017cellular_componentsarcomere
H0030235molecular_functionnitric-oxide synthase regulator activity
H0030426cellular_componentgrowth cone
H0030672cellular_componentsynaptic vesicle membrane
H0031432molecular_functiontitin binding
H0031800molecular_functiontype 3 metabotropic glutamate receptor binding
H0031966cellular_componentmitochondrial membrane
H0031982cellular_componentvesicle
H0032465biological_processregulation of cytokinesis
H0032991cellular_componentprotein-containing complex
H0034704cellular_componentcalcium channel complex
H0043209cellular_componentmyelin sheath
H0043539molecular_functionprotein serine/threonine kinase activator activity
H0043548molecular_functionphosphatidylinositol 3-kinase binding
H0044305cellular_componentcalyx of Held
H0044325molecular_functiontransmembrane transporter binding
H0046872molecular_functionmetal ion binding
H0048306molecular_functioncalcium-dependent protein binding
H0050848biological_processregulation of calcium-mediated signaling
H0050998molecular_functionnitric-oxide synthase binding
H0051412biological_processresponse to corticosterone
H0051592biological_processresponse to calcium ion
H0055117biological_processregulation of cardiac muscle contraction
H0060291biological_processlong-term synaptic potentiation
H0072542molecular_functionprotein phosphatase activator activity
H0090150biological_processestablishment of protein localization to membrane
H0090151biological_processestablishment of protein localization to mitochondrial membrane
H0097225cellular_componentsperm midpiece
H0097720biological_processcalcineurin-mediated signaling
H0098685cellular_componentSchaffer collateral - CA1 synapse
H0098901biological_processregulation of cardiac muscle cell action potential
H0099523cellular_componentpresynaptic cytosol
H0099524cellular_componentpostsynaptic cytosol
H0140238biological_processpresynaptic endocytosis
H0141110molecular_functiontransporter inhibitor activity
H1900242biological_processregulation of synaptic vesicle endocytosis
H1901842biological_processnegative regulation of high voltage-gated calcium channel activity
H1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
H1902494cellular_componentcatalytic complex
H1905913biological_processnegative regulation of calcium ion export across plasma membrane
H2000300biological_processregulation of synaptic vesicle exocytosis
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue PT5 A 701
ChainResidue
AGLU92
APRO94
AHIS102
AARG150
ALYS172
APHE174
AARG216
AMET217
AARG219

site_idAC2
Number of Residues4
Detailsbinding site for residue FBX A 702
ChainResidue
ALEU305
ASER309
GPHE311
GLEU318

site_idAC3
Number of Residues8
Detailsbinding site for residue K A 703
ChainResidue
AGLY285
ATYR286
CGLY285
CTYR286
EGLY285
ETYR286
GGLY285
GTYR286

site_idAC4
Number of Residues8
Detailsbinding site for residue K A 704
ChainResidue
ATHR283
AILE284
CTHR283
CILE284
ETHR283
EILE284
GTHR283
GILE284

site_idAC5
Number of Residues4
Detailsbinding site for residue K A 705
ChainResidue
ATHR283
CTHR283
ETHR283
GTHR283

site_idAC6
Number of Residues5
Detailsbinding site for residue FBX C 701
ChainResidue
APHE311
ALEU318
CLEU305
CSER309
GPHE110

site_idAC7
Number of Residues10
Detailsbinding site for residue PT5 C 702
ChainResidue
CGLU92
CPRO94
CHIS102
CVAL103
CARG150
CLYS172
CPHE174
CARG216
CMET217
CARG219

site_idAC8
Number of Residues4
Detailsbinding site for residue FBX E 701
ChainResidue
APHE110
CPHE311
ELEU305
ESER309

site_idAC9
Number of Residues8
Detailsbinding site for residue PT5 E 702
ChainResidue
EGLU92
EPRO94
EARG150
ELYS172
EPHE174
EARG216
EMET217
EARG219

site_idAD1
Number of Residues6
Detailsbinding site for residue FBX G 701
ChainResidue
CPHE110
ETRP242
EPHE311
ELEU318
GLEU305
GSER309

site_idAD2
Number of Residues9
Detailsbinding site for residue PT5 G 702
ChainResidue
GGLU92
GPRO94
GHIS102
GARG150
GLYS172
GPHE174
GARG216
GMET217
GARG219

Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL
ChainResidueDetails
BASP20-LEU32
BASP56-PHE68
BASP93-LEU105
BASP129-PHE141

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues80
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:1474585
ChainResidueDetails
BASP20
BGLU67
BASP93
BASP95
BASN97
BTYR99
BGLU104
BASP129
BASP131
BASP133
BGLN135
BASP22
BGLU140
DASP20
DASP22
DASP24
DTHR26
DGLU31
DASP56
DASP58
DASN60
DTHR62
BASP24
DGLU67
DASP93
DASP95
DASN97
DTYR99
DGLU104
DASP129
DASP131
DASP133
DGLN135
BTHR26
DGLU140
FASP20
FASP22
FASP24
FTHR26
FGLU31
FASP56
FASP58
FASN60
FTHR62
BGLU31
FGLU67
FASP93
FASP95
FASN97
FTYR99
FGLU104
FASP129
FASP131
FASP133
FGLN135
BASP56
FGLU140
HASP20
HASP22
HASP24
HTHR26
HGLU31
HASP56
HASP58
HASN60
HTHR62
BASP58
HGLU67
HASP93
HASP95
HASN97
HTYR99
HGLU104
HASP129
HASP131
HASP133
HGLN135
BASN60
HGLU140
BTHR62

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: N-acetylalanine => ECO:0000269|PubMed:7093203, ECO:0000269|Ref.7, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712
ChainResidueDetails
BALA1
DALA1
FALA1
HALA1
ETHR-190
EGLY-188
GTHR-190
GGLY-188

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861
ChainResidueDetails
BLYS21
ESER153-ARG168
ETRP224-SER235
EALA323-ASP695
GMET1-GLY96
GSER153-ARG168
GTRP224-SER235
GALA323-ASP695
DLYS21
FLYS21
HLYS21
CMET1-GLY96
CSER153-ARG168
CTRP224-SER235
CALA323-ASP695
EMET1-GLY96

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphothreonine; by CaMK4 => ECO:0000250|UniProtKB:P0DP31
ChainResidueDetails
BTHR44
DTHR44
FTHR44
HTHR44

site_idSWS_FT_FI5
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER81
EGLY192-ALA202
EALA259-TYR270
ETHR293
GSER119-ASN129
GGLY192-ALA202
GALA259-TYR270
GTHR293
DSER81
FSER81
HSER81
CSER119-ASN129
CGLY192-ALA202
CALA259-TYR270
CTHR293
ESER119-ASN129

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
BLYS94
DLYS94
FLYS94
HLYS94

site_idSWS_FT_FI7
Number of Residues4
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332
ChainResidueDetails
BTYR99
DTYR99
FTYR99
HTYR99

site_idSWS_FT_FI8
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
BSER101
DSER101
FSER101
HSER101

site_idSWS_FT_FI9
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569
ChainResidueDetails
BTHR110
DTHR110
FTHR110
HTHR110

site_idSWS_FT_FI10
Number of Residues4
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0007744|PubMed:24129315
ChainResidueDetails
BLYS115
DLYS115
FLYS115
HLYS115

site_idSWS_FT_FI11
Number of Residues4
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332
ChainResidueDetails
BTYR138
DTYR138
FTYR138
HTYR138

site_idSWS_FT_FI12
Number of Residues8
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62157
ChainResidueDetails
BLYS21
ELYS172
EARG219
ELYS225
GARG93
GLYS172
GARG219
GLYS225
ALYS172
DLYS21
ALYS225
FLYS21
CLYS172
HLYS21
CLYS225
EARG93

site_idSWS_FT_FI13
Number of Residues12
DetailsBINDING: in chain A => ECO:0000269|PubMed:34767770, ECO:0007744|PDB:7VNP
ChainResidueDetails
AARG220
GARG220
GHIS330
GLYS333
AHIS330
ALYS333
CARG220
CHIS330
CLYS333
EARG220
EHIS330
ELYS333

site_idSWS_FT_FI14
Number of Residues4
DetailsBINDING: in chain B => ECO:0000269|PubMed:34767770, ECO:0007744|PDB:7VNP
ChainResidueDetails
ASER235
CSER235
ESER235
GSER235

237423

PDB entries from 2025-06-11

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