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7BLN

VPS35/VPS29 arch of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005764cellular_componentlysosome
A0005765cellular_componentlysosomal membrane
A0005768cellular_componentendosome
A0005769cellular_componentearly endosome
A0005770cellular_componentlate endosome
A0005829cellular_componentcytosol
A0006886biological_processintracellular protein transport
A0007040biological_processlysosome organization
A0010008cellular_componentendosome membrane
A0010628biological_processpositive regulation of gene expression
A0010629biological_processnegative regulation of gene expression
A0010821biological_processregulation of mitochondrion organization
A0014069cellular_componentpostsynaptic density
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016055biological_processWnt signaling pathway
A0016241biological_processregulation of macroautophagy
A0030904cellular_componentretromer complex
A0030906cellular_componentretromer, cargo-selective complex
A0031647biological_processregulation of protein stability
A0031648biological_processprotein destabilization
A0031748molecular_functionD1 dopamine receptor binding
A0032456biological_processendocytic recycling
A0032463biological_processnegative regulation of protein homooligomerization
A0033365biological_processprotein localization to organelle
A0036010biological_processprotein localization to endosome
A0042147biological_processretrograde transport, endosome to Golgi
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043653biological_processmitochondrial fragmentation involved in apoptotic process
A0045056biological_processtranscytosis
A0045202cellular_componentsynapse
A0045732biological_processpositive regulation of protein catabolic process
A0048471cellular_componentperinuclear region of cytoplasm
A0050728biological_processnegative regulation of inflammatory response
A0050804biological_processmodulation of chemical synaptic transmission
A0050882biological_processvoluntary musculoskeletal movement
A0051246biological_processregulation of protein metabolic process
A0060161biological_processpositive regulation of dopamine receptor signaling pathway
A0061357biological_processpositive regulation of Wnt protein secretion
A0070062cellular_componentextracellular exosome
A0090128biological_processregulation of synapse maturation
A0090141biological_processpositive regulation of mitochondrial fission
A0090263biological_processpositive regulation of canonical Wnt signaling pathway
A0090326biological_processpositive regulation of locomotion involved in locomotory behavior
A0097422cellular_componenttubular endosome
A0098691cellular_componentdopaminergic synapse
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A0098887biological_processneurotransmitter receptor transport, endosome to postsynaptic membrane
A0098978cellular_componentglutamatergic synapse
A0099003biological_processvesicle-mediated transport in synapse
A0099073cellular_componentmitochondrion-derived vesicle
A0099074biological_processmitochondrion to lysosome vesicle-mediated transport
A0099639biological_processneurotransmitter receptor transport, endosome to plasma membrane
A0150052biological_processregulation of postsynapse assembly
A1902823biological_processnegative regulation of late endosome to lysosome transport
A1902950biological_processregulation of dendritic spine maintenance
A1903181biological_processpositive regulation of dopamine biosynthetic process
A1903828biological_processnegative regulation of protein localization
A1904377biological_processpositive regulation of protein localization to cell periphery
A1905166biological_processnegative regulation of lysosomal protein catabolic process
A1905606biological_processregulation of presynapse assembly
A2000331biological_processregulation of terminal button organization
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005768cellular_componentendosome
B0005769cellular_componentearly endosome
B0005770cellular_componentlate endosome
B0005829cellular_componentcytosol
B0006886biological_processintracellular protein transport
B0010008cellular_componentendosome membrane
B0010506biological_processregulation of autophagy
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0030904cellular_componentretromer complex
B0030906cellular_componentretromer, cargo-selective complex
B0032456biological_processendocytic recycling
B0042147biological_processretrograde transport, endosome to Golgi
B0043231cellular_componentintracellular membrane-bounded organelle
B0046872molecular_functionmetal ion binding
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005764cellular_componentlysosome
C0005765cellular_componentlysosomal membrane
C0005768cellular_componentendosome
C0005769cellular_componentearly endosome
C0005770cellular_componentlate endosome
C0005829cellular_componentcytosol
C0006886biological_processintracellular protein transport
C0007040biological_processlysosome organization
C0010008cellular_componentendosome membrane
C0010628biological_processpositive regulation of gene expression
C0010629biological_processnegative regulation of gene expression
C0010821biological_processregulation of mitochondrion organization
C0014069cellular_componentpostsynaptic density
C0015031biological_processprotein transport
C0016020cellular_componentmembrane
C0016055biological_processWnt signaling pathway
C0016241biological_processregulation of macroautophagy
C0030904cellular_componentretromer complex
C0030906cellular_componentretromer, cargo-selective complex
C0031647biological_processregulation of protein stability
C0031648biological_processprotein destabilization
C0031748molecular_functionD1 dopamine receptor binding
C0032456biological_processendocytic recycling
C0032463biological_processnegative regulation of protein homooligomerization
C0033365biological_processprotein localization to organelle
C0036010biological_processprotein localization to endosome
C0042147biological_processretrograde transport, endosome to Golgi
C0043005cellular_componentneuron projection
C0043025cellular_componentneuronal cell body
C0043653biological_processmitochondrial fragmentation involved in apoptotic process
C0045056biological_processtranscytosis
C0045202cellular_componentsynapse
C0045732biological_processpositive regulation of protein catabolic process
C0048471cellular_componentperinuclear region of cytoplasm
C0050728biological_processnegative regulation of inflammatory response
C0050804biological_processmodulation of chemical synaptic transmission
C0050882biological_processvoluntary musculoskeletal movement
C0051246biological_processregulation of protein metabolic process
C0060161biological_processpositive regulation of dopamine receptor signaling pathway
C0061357biological_processpositive regulation of Wnt protein secretion
C0070062cellular_componentextracellular exosome
C0090128biological_processregulation of synapse maturation
C0090141biological_processpositive regulation of mitochondrial fission
C0090263biological_processpositive regulation of canonical Wnt signaling pathway
C0090326biological_processpositive regulation of locomotion involved in locomotory behavior
C0097422cellular_componenttubular endosome
C0098691cellular_componentdopaminergic synapse
C0098793cellular_componentpresynapse
C0098794cellular_componentpostsynapse
C0098887biological_processneurotransmitter receptor transport, endosome to postsynaptic membrane
C0098978cellular_componentglutamatergic synapse
C0099003biological_processvesicle-mediated transport in synapse
C0099073cellular_componentmitochondrion-derived vesicle
C0099074biological_processmitochondrion to lysosome vesicle-mediated transport
C0099639biological_processneurotransmitter receptor transport, endosome to plasma membrane
C0150052biological_processregulation of postsynapse assembly
C1902823biological_processnegative regulation of late endosome to lysosome transport
C1902950biological_processregulation of dendritic spine maintenance
C1903181biological_processpositive regulation of dopamine biosynthetic process
C1903828biological_processnegative regulation of protein localization
C1904377biological_processpositive regulation of protein localization to cell periphery
C1905166biological_processnegative regulation of lysosomal protein catabolic process
C1905606biological_processregulation of presynapse assembly
C2000331biological_processregulation of terminal button organization
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005768cellular_componentendosome
D0005769cellular_componentearly endosome
D0005770cellular_componentlate endosome
D0005829cellular_componentcytosol
D0006886biological_processintracellular protein transport
D0010008cellular_componentendosome membrane
D0010506biological_processregulation of autophagy
D0015031biological_processprotein transport
D0016020cellular_componentmembrane
D0030904cellular_componentretromer complex
D0030906cellular_componentretromer, cargo-selective complex
D0032456biological_processendocytic recycling
D0042147biological_processretrograde transport, endosome to Golgi
D0043231cellular_componentintracellular membrane-bounded organelle
D0046872molecular_functionmetal ion binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231
ChainResidueDetails
ASER7
DASN39
DASP62
DHIS86
DHIS115
DHIS117
CSER7
BASN39
BASP62
BHIS86
BHIS115
BHIS117
DASP8
DHIS10

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9EQH3
ChainResidueDetails
ASER783
CSER783

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q9EQH3
ChainResidueDetails
ATYR791
CTYR791

227111

PDB entries from 2024-11-06

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