7BIR

Inhibitor of MDM2-p53 Interaction

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 201

Chain	Residue
A	LYS31
A	GLN71
A	GLN72
A	HIS73
A	HOH304
A	HOH317

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site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 202

Chain	Residue
A	HOH320
A	ARG97
A	ARG97
A	HOH301

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site_id	AC3
Number of Residues	10
Details	binding site for residue TUZ A 203

Chain	Residue
A	PRO32
A	LEU54
A	PHE55
A	GLY58
A	GLN59
A	ILE61
A	MET62
A	GLN72
A	VAL93
A	HIS96

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