7BFP

Structure of the Integrator cleavage module with INTS4/9/11

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005829	cellular_component	cytosol
A	0016180	biological_process	snRNA processing
A	0030512	biological_process	negative regulation of transforming growth factor beta receptor signaling pathway
A	0032039	cellular_component	integrator complex
A	0034243	biological_process	regulation of transcription elongation by RNA polymerase II
A	0034472	biological_process	snRNA 3'-end processing
B	0004521	molecular_function	RNA endonuclease activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0016180	biological_process	snRNA processing
B	0016787	molecular_function	hydrolase activity
B	0032039	cellular_component	integrator complex
B	0034243	biological_process	regulation of transcription elongation by RNA polymerase II
B	0072562	cellular_component	blood microparticle
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0016180	biological_process	snRNA processing
C	0032039	cellular_component	integrator complex
C	0034243	biological_process	regulation of transcription elongation by RNA polymerase II

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8CIM8

Chain	Residue	Details
C	LYS26

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211, ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
C	LYS791

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