7B04
Structure of Nitrite oxidoreductase (Nxr) from the anammox bacterium Kuenenia stuttgartiensis.
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0009061 | biological_process | anaerobic respiration |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030313 | cellular_component | cell envelope |
| A | 0044222 | cellular_component | anammoxosome |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0044222 | cellular_component | anammoxosome |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| C | 0020037 | molecular_function | heme binding |
| C | 0042597 | cellular_component | periplasmic space |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0009061 | biological_process | anaerobic respiration |
| D | 0016020 | cellular_component | membrane |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0030313 | cellular_component | cell envelope |
| D | 0044222 | cellular_component | anammoxosome |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| D | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0044222 | cellular_component | anammoxosome |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0051536 | molecular_function | iron-sulfur cluster binding |
| E | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| F | 0020037 | molecular_function | heme binding |
| F | 0042597 | cellular_component | periplasmic space |
| G | 0009055 | molecular_function | electron transfer activity |
| G | 0009061 | biological_process | anaerobic respiration |
| G | 0016020 | cellular_component | membrane |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0030313 | cellular_component | cell envelope |
| G | 0044222 | cellular_component | anammoxosome |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0051536 | molecular_function | iron-sulfur cluster binding |
| G | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| G | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0044222 | cellular_component | anammoxosome |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0051536 | molecular_function | iron-sulfur cluster binding |
| H | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| I | 0020037 | molecular_function | heme binding |
| I | 0042597 | cellular_component | periplasmic space |
| J | 0009055 | molecular_function | electron transfer activity |
| J | 0009061 | biological_process | anaerobic respiration |
| J | 0016020 | cellular_component | membrane |
| J | 0016491 | molecular_function | oxidoreductase activity |
| J | 0030313 | cellular_component | cell envelope |
| J | 0044222 | cellular_component | anammoxosome |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0051536 | molecular_function | iron-sulfur cluster binding |
| J | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| J | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| K | 0016491 | molecular_function | oxidoreductase activity |
| K | 0044222 | cellular_component | anammoxosome |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0051536 | molecular_function | iron-sulfur cluster binding |
| K | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| L | 0020037 | molecular_function | heme binding |
| L | 0042597 | cellular_component | periplasmic space |
| M | 0009055 | molecular_function | electron transfer activity |
| M | 0009061 | biological_process | anaerobic respiration |
| M | 0016020 | cellular_component | membrane |
| M | 0016491 | molecular_function | oxidoreductase activity |
| M | 0030313 | cellular_component | cell envelope |
| M | 0044222 | cellular_component | anammoxosome |
| M | 0046872 | molecular_function | metal ion binding |
| M | 0051536 | molecular_function | iron-sulfur cluster binding |
| M | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| M | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| N | 0016491 | molecular_function | oxidoreductase activity |
| N | 0044222 | cellular_component | anammoxosome |
| N | 0046872 | molecular_function | metal ion binding |
| N | 0051536 | molecular_function | iron-sulfur cluster binding |
| N | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| O | 0020037 | molecular_function | heme binding |
| O | 0042597 | cellular_component | periplasmic space |
| P | 0009055 | molecular_function | electron transfer activity |
| P | 0009061 | biological_process | anaerobic respiration |
| P | 0016020 | cellular_component | membrane |
| P | 0016491 | molecular_function | oxidoreductase activity |
| P | 0030313 | cellular_component | cell envelope |
| P | 0044222 | cellular_component | anammoxosome |
| P | 0046872 | molecular_function | metal ion binding |
| P | 0051536 | molecular_function | iron-sulfur cluster binding |
| P | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| P | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| Q | 0016491 | molecular_function | oxidoreductase activity |
| Q | 0044222 | cellular_component | anammoxosome |
| Q | 0046872 | molecular_function | metal ion binding |
| Q | 0051536 | molecular_function | iron-sulfur cluster binding |
| Q | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| R | 0020037 | molecular_function | heme binding |
| R | 0042597 | cellular_component | periplasmic space |
| S | 0009055 | molecular_function | electron transfer activity |
| S | 0009061 | biological_process | anaerobic respiration |
| S | 0016020 | cellular_component | membrane |
| S | 0016491 | molecular_function | oxidoreductase activity |
| S | 0030313 | cellular_component | cell envelope |
| S | 0044222 | cellular_component | anammoxosome |
| S | 0046872 | molecular_function | metal ion binding |
| S | 0051536 | molecular_function | iron-sulfur cluster binding |
| S | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| S | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| T | 0016491 | molecular_function | oxidoreductase activity |
| T | 0044222 | cellular_component | anammoxosome |
| T | 0046872 | molecular_function | metal ion binding |
| T | 0051536 | molecular_function | iron-sulfur cluster binding |
| T | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| U | 0020037 | molecular_function | heme binding |
| U | 0042597 | cellular_component | periplasmic space |
| V | 0009055 | molecular_function | electron transfer activity |
| V | 0009061 | biological_process | anaerobic respiration |
| V | 0016020 | cellular_component | membrane |
| V | 0016491 | molecular_function | oxidoreductase activity |
| V | 0030313 | cellular_component | cell envelope |
| V | 0044222 | cellular_component | anammoxosome |
| V | 0046872 | molecular_function | metal ion binding |
| V | 0051536 | molecular_function | iron-sulfur cluster binding |
| V | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| V | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| W | 0016491 | molecular_function | oxidoreductase activity |
| W | 0044222 | cellular_component | anammoxosome |
| W | 0046872 | molecular_function | metal ion binding |
| W | 0051536 | molecular_function | iron-sulfur cluster binding |
| W | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| X | 0020037 | molecular_function | heme binding |
| X | 0042597 | cellular_component | periplasmic space |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 A 501 |
| Chain | Residue |
| A | CYS45 |
| A | TRP49 |
| A | ASN61 |
| A | CYS235 |
| A | ILE236 |
| A | ALA237 |
| A | CYS238 |
| A | THR256 |
| A | CYS258 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 A 502 |
| Chain | Residue |
| A | CYS175 |
| A | ASN176 |
| A | HIS177 |
| A | CYS178 |
| A | PRO181 |
| A | GLY182 |
| A | CYS183 |
| A | CYS218 |
| A | TYR220 |
| A | PRO223 |
| A | LYS234 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue SF4 A 503 |
| Chain | Residue |
| A | CYS35 |
| A | ILE36 |
| A | ALA37 |
| A | CYS38 |
| A | GLN39 |
| A | CYS41 |
| A | VAL63 |
| A | GLN172 |
| A | CYS262 |
| A | VAL263 |
| A | ILE266 |
| A | ARG267 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue F3S A 504 |
| Chain | Residue |
| A | CYS187 |
| A | ARG189 |
| A | ILE192 |
| A | CYS208 |
| A | ARG209 |
| A | GLY210 |
| A | TYR211 |
| A | ARG212 |
| A | LYS213 |
| A | CYS214 |
| A | SER232 |
| site_id | AC5 |
| Number of Residues | 28 |
| Details | binding site for residue MD1 B 5801 |
| Chain | Residue |
| B | ASN70 |
| B | ARG124 |
| B | LYS236 |
| B | HIS273 |
| B | ASP275 |
| B | HIS531 |
| B | ASN653 |
| B | VAL654 |
| B | ASN655 |
| B | ASN659 |
| B | LYS661 |
| B | THR680 |
| B | ASP681 |
| B | THR685 |
| B | ASN698 |
| B | TRP700 |
| B | ASP734 |
| B | THR915 |
| B | LYS917 |
| B | VAL922 |
| B | HIS923 |
| B | SER924 |
| B | GLN925 |
| B | HIS1020 |
| B | GLN1057 |
| B | PRO1098 |
| B | MD15802 |
| B | MO5803 |
| site_id | AC6 |
| Number of Residues | 34 |
| Details | binding site for residue MD1 B 5802 |
| Chain | Residue |
| B | VAL922 |
| B | HIS923 |
| B | LYS1099 |
| B | MD15801 |
| B | MO5803 |
| B | HOH5925 |
| B | ASP71 |
| B | LYS117 |
| B | ASP275 |
| B | THR305 |
| B | GLY306 |
| B | LYS307 |
| B | ASN308 |
| B | GLU311 |
| B | ASN312 |
| B | LYS313 |
| B | MET314 |
| B | ILE333 |
| B | PRO335 |
| B | GLU336 |
| B | ASN352 |
| B | ASN353 |
| B | ASP355 |
| B | GLY526 |
| B | GLU527 |
| B | GLY528 |
| B | VAL529 |
| B | TYR532 |
| B | GLY564 |
| B | VAL914 |
| B | PRO916 |
| B | LYS917 |
| B | SER918 |
| B | THR921 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue MO B 5803 |
| Chain | Residue |
| B | ASP275 |
| B | MD15801 |
| B | MD15802 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 B 5804 |
| Chain | Residue |
| B | CYS67 |
| B | ASP71 |
| B | CYS75 |
| B | ILE77 |
| B | MET114 |
| B | CYS115 |
| site_id | AC9 |
| Number of Residues | 24 |
| Details | binding site for residue HEM C 401 |
| Chain | Residue |
| A | ARG189 |
| A | ARG209 |
| A | TYR211 |
| C | GLN84 |
| C | LYS86 |
| C | ALA135 |
| C | LEU136 |
| C | MET137 |
| C | ARG154 |
| C | MET155 |
| C | LEU164 |
| C | HIS166 |
| C | PHE241 |
| C | GLY242 |
| C | THR243 |
| C | LEU244 |
| C | ASN290 |
| C | MET291 |
| C | ALA292 |
| C | TRP294 |
| C | ASN302 |
| C | LYS305 |
| C | ILE307 |
| C | HOH510 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 402 |
| Chain | Residue |
| C | ASP117 |
| C | THR119 |
| C | ASN121 |
| C | ASP132 |
| C | ASN295 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 403 |
| Chain | Residue |
| C | ASP235 |
| C | GLN247 |
| C | HIS249 |
| C | ASP251 |
| C | ASP275 |
| C | ASP278 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 D 501 |
| Chain | Residue |
| D | CYS45 |
| D | ASN61 |
| D | ILE174 |
| D | CYS235 |
| D | ILE236 |
| D | CYS238 |
| D | ARG257 |
| D | CYS258 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 D 502 |
| Chain | Residue |
| D | CYS175 |
| D | ASN176 |
| D | CYS178 |
| D | PRO181 |
| D | GLY182 |
| D | CYS183 |
| D | CYS218 |
| D | LYS222 |
| D | LYS234 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 D 503 |
| Chain | Residue |
| D | CYS35 |
| D | ALA37 |
| D | CYS38 |
| D | GLN39 |
| D | CYS41 |
| D | VAL63 |
| D | CYS262 |
| D | ILE266 |
| D | ARG267 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | binding site for residue F3S D 504 |
| Chain | Residue |
| D | CYS187 |
| D | ILE192 |
| D | CYS208 |
| D | ARG209 |
| D | GLY210 |
| D | TYR211 |
| D | ARG212 |
| D | LYS213 |
| D | CYS214 |
| D | SER232 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue MO E 5803 |
| Chain | Residue |
| E | HIS273 |
| E | ASP275 |
| E | MD15801 |
| E | MD15802 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 E 5804 |
| Chain | Residue |
| E | CYS67 |
| E | PRO69 |
| E | ASP71 |
| E | ALA74 |
| E | CYS75 |
| E | MET114 |
| E | CYS115 |
| E | GLY118 |
| site_id | AD9 |
| Number of Residues | 18 |
| Details | binding site for residue HEM F 401 |
| Chain | Residue |
| D | ARG209 |
| D | TYR211 |
| F | GLN84 |
| F | ALA135 |
| F | MET137 |
| F | ARG154 |
| F | MET155 |
| F | HIS166 |
| F | PHE241 |
| F | GLY242 |
| F | THR243 |
| F | LEU244 |
| F | ASN290 |
| F | MET291 |
| F | ALA292 |
| F | TRP294 |
| F | ASN302 |
| F | LYS305 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue CA F 402 |
| Chain | Residue |
| F | ASP235 |
| F | GLN247 |
| F | HIS249 |
| F | ASP251 |
| F | ASP275 |
| F | ASP278 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CA F 403 |
| Chain | Residue |
| F | ASP117 |
| F | THR119 |
| F | ASN121 |
| F | ASP132 |
| F | ASN295 |
| site_id | AE3 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 G 501 |
| Chain | Residue |
| G | CYS45 |
| G | ASN61 |
| G | ILE174 |
| G | CYS235 |
| G | ILE236 |
| G | ALA237 |
| G | CYS238 |
| G | THR256 |
| G | CYS258 |
| site_id | AE4 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 G 502 |
| Chain | Residue |
| G | CYS175 |
| G | ASN176 |
| G | HIS177 |
| G | CYS178 |
| G | PRO181 |
| G | GLY182 |
| G | CYS183 |
| G | CYS218 |
| G | TYR220 |
| G | PRO223 |
| G | LYS234 |
| site_id | AE5 |
| Number of Residues | 12 |
| Details | binding site for residue SF4 G 503 |
| Chain | Residue |
| G | CYS35 |
| G | ILE36 |
| G | ALA37 |
| G | CYS38 |
| G | GLN39 |
| G | THR40 |
| G | CYS41 |
| G | VAL63 |
| G | CYS262 |
| G | VAL263 |
| G | ILE266 |
| G | ARG267 |
| site_id | AE6 |
| Number of Residues | 10 |
| Details | binding site for residue F3S G 504 |
| Chain | Residue |
| G | CYS187 |
| G | ILE192 |
| G | CYS208 |
| G | ARG209 |
| G | GLY210 |
| G | TYR211 |
| G | ARG212 |
| G | LYS213 |
| G | CYS214 |
| G | SER232 |
| site_id | AE7 |
| Number of Residues | 31 |
| Details | binding site for residue MD1 H 5801 |
| Chain | Residue |
| H | ASN70 |
| H | LYS236 |
| H | HIS273 |
| H | ASP275 |
| H | HIS531 |
| H | THR652 |
| H | ASN653 |
| H | VAL654 |
| H | ASN655 |
| H | ASN659 |
| H | LYS661 |
| H | THR680 |
| H | ASP681 |
| H | ILE682 |
| H | ASN698 |
| H | TRP700 |
| H | ASP734 |
| H | THR915 |
| H | LYS917 |
| H | VAL922 |
| H | HIS923 |
| H | SER924 |
| H | GLN925 |
| H | HIS1020 |
| H | GLN1057 |
| H | THR1060 |
| H | PRO1098 |
| H | MD15802 |
| H | MO5803 |
| H | HOH5909 |
| H | HOH5931 |
| site_id | AE8 |
| Number of Residues | 33 |
| Details | binding site for residue MD1 H 5802 |
| Chain | Residue |
| H | ASN70 |
| H | LYS117 |
| H | ASP275 |
| H | THR305 |
| H | GLY306 |
| H | LYS307 |
| H | ASN308 |
| H | GLU311 |
| H | ASN312 |
| H | LYS313 |
| H | MET314 |
| H | ILE333 |
| H | PRO335 |
| H | GLU336 |
| H | ASN352 |
| H | ASN353 |
| H | ASP355 |
| H | GLY526 |
| H | GLU527 |
| H | GLY528 |
| H | TYR532 |
| H | GLY564 |
| H | VAL914 |
| H | PRO916 |
| H | LYS917 |
| H | SER918 |
| H | THR921 |
| H | HIS923 |
| H | LYS1099 |
| H | MD15801 |
| H | MO5803 |
| H | HOH5929 |
| H | HOH5931 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue MO H 5803 |
| Chain | Residue |
| H | ASP275 |
| H | MD15801 |
| H | MD15802 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue SF4 H 5804 |
| Chain | Residue |
| H | CYS67 |
| H | PRO69 |
| H | ASP71 |
| H | CYS75 |
| H | CYS115 |
| site_id | AF2 |
| Number of Residues | 21 |
| Details | binding site for residue HEM I 401 |
| Chain | Residue |
| G | PRO188 |
| G | ARG189 |
| G | ARG209 |
| G | TYR211 |
| I | GLN84 |
| I | MET137 |
| I | ARG154 |
| I | MET155 |
| I | LEU164 |
| I | HIS166 |
| I | PHE241 |
| I | GLY242 |
| I | THR243 |
| I | LEU244 |
| I | ASN290 |
| I | MET291 |
| I | ALA292 |
| I | ASN302 |
| I | LYS305 |
| I | ILE307 |
| I | HOH509 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue CA I 402 |
| Chain | Residue |
| I | ASP117 |
| I | THR119 |
| I | ASN121 |
| I | ASP132 |
| I | ASN295 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue CA I 403 |
| Chain | Residue |
| I | ASP235 |
| I | GLN247 |
| I | HIS249 |
| I | ASP251 |
| I | ASP275 |
| I | ASP278 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 J 501 |
| Chain | Residue |
| J | CYS45 |
| J | CYS235 |
| J | ILE236 |
| J | ALA237 |
| J | CYS238 |
| J | THR256 |
| J | CYS258 |
| site_id | AF6 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 J 502 |
| Chain | Residue |
| J | CYS175 |
| J | ASN176 |
| J | HIS177 |
| J | CYS178 |
| J | PRO181 |
| J | GLY182 |
| J | CYS183 |
| J | CYS218 |
| J | PRO223 |
| J | LYS234 |
| site_id | AF7 |
| Number of Residues | 13 |
| Details | binding site for residue SF4 J 503 |
| Chain | Residue |
| J | CYS35 |
| J | ILE36 |
| J | ALA37 |
| J | CYS38 |
| J | GLN39 |
| J | CYS41 |
| J | VAL63 |
| J | GLN172 |
| J | CYS262 |
| J | VAL263 |
| J | GLY264 |
| J | ILE266 |
| J | ARG267 |
| site_id | AF8 |
| Number of Residues | 11 |
| Details | binding site for residue F3S J 504 |
| Chain | Residue |
| J | CYS187 |
| J | ARG189 |
| J | ILE192 |
| J | CYS208 |
| J | ARG209 |
| J | GLY210 |
| J | TYR211 |
| J | ARG212 |
| J | LYS213 |
| J | CYS214 |
| J | SER232 |
| site_id | AF9 |
| Number of Residues | 33 |
| Details | binding site for residue MD1 K 5801 |
| Chain | Residue |
| K | ASN70 |
| K | LYS236 |
| K | HIS273 |
| K | ASP275 |
| K | HIS531 |
| K | THR652 |
| K | ASN653 |
| K | VAL654 |
| K | ASN655 |
| K | ASN659 |
| K | LYS661 |
| K | THR680 |
| K | ASP681 |
| K | ILE682 |
| K | THR685 |
| K | ALA697 |
| K | ASN698 |
| K | TRP700 |
| K | ASP734 |
| K | THR915 |
| K | LYS917 |
| K | VAL922 |
| K | HIS923 |
| K | SER924 |
| K | GLN925 |
| K | HIS1020 |
| K | GLN1057 |
| K | THR1060 |
| K | PRO1098 |
| K | MD15802 |
| K | MO5803 |
| K | HOH5913 |
| K | HOH5933 |
| site_id | AG1 |
| Number of Residues | 35 |
| Details | binding site for residue MD1 K 5802 |
| Chain | Residue |
| K | ASN70 |
| K | ASP71 |
| K | LYS117 |
| K | ASP275 |
| K | THR305 |
| K | GLY306 |
| K | LYS307 |
| K | ASN308 |
| K | GLU311 |
| K | ASN312 |
| K | MET314 |
| K | ILE333 |
| K | PRO335 |
| K | GLU336 |
| K | ASN352 |
| K | ASN353 |
| K | ASP355 |
| K | GLY526 |
| K | GLU527 |
| K | GLY528 |
| K | VAL529 |
| K | TYR532 |
| K | GLY564 |
| K | VAL914 |
| K | PRO916 |
| K | LYS917 |
| K | SER918 |
| K | ARG919 |
| K | THR921 |
| K | VAL922 |
| K | HIS923 |
| K | LYS1099 |
| K | MD15801 |
| K | MO5803 |
| K | HOH5930 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue MO K 5803 |
| Chain | Residue |
| K | ASP275 |
| K | MD15801 |
| K | MD15802 |
| site_id | AG3 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 K 5804 |
| Chain | Residue |
| K | CYS67 |
| K | PRO69 |
| K | ASP71 |
| K | CYS75 |
| K | ILE77 |
| K | MET114 |
| K | CYS115 |
| K | GLY118 |
| site_id | AG4 |
| Number of Residues | 24 |
| Details | binding site for residue HEM L 401 |
| Chain | Residue |
| J | ARG189 |
| J | ARG209 |
| J | TYR211 |
| L | GLN84 |
| L | LYS86 |
| L | ALA135 |
| L | MET137 |
| L | ARG154 |
| L | MET155 |
| L | LEU164 |
| L | HIS166 |
| L | PHE241 |
| L | GLY242 |
| L | THR243 |
| L | LEU244 |
| L | ASN290 |
| L | MET291 |
| L | ALA292 |
| L | TRP294 |
| L | ASN302 |
| L | GLY303 |
| L | LYS305 |
| L | ILE307 |
| L | HOH507 |
| site_id | AG5 |
| Number of Residues | 5 |
| Details | binding site for residue CA L 402 |
| Chain | Residue |
| L | ASP117 |
| L | THR119 |
| L | ASN121 |
| L | ASP132 |
| L | ASN295 |
| site_id | AG6 |
| Number of Residues | 6 |
| Details | binding site for residue CA L 403 |
| Chain | Residue |
| L | ASP235 |
| L | GLN247 |
| L | HIS249 |
| L | ASP251 |
| L | ASP275 |
| L | ASP278 |
| site_id | AG7 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 M 501 |
| Chain | Residue |
| M | CYS45 |
| M | TRP49 |
| M | TRP60 |
| M | CYS235 |
| M | ALA237 |
| M | CYS238 |
| M | THR256 |
| M | CYS258 |
| site_id | AG8 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 M 502 |
| Chain | Residue |
| M | CYS175 |
| M | ASN176 |
| M | HIS177 |
| M | CYS178 |
| M | PRO181 |
| M | GLY182 |
| M | CYS183 |
| M | CYS218 |
| M | PRO223 |
| M | LYS234 |
| site_id | AG9 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 M 503 |
| Chain | Residue |
| M | CYS35 |
| M | ALA37 |
| M | CYS38 |
| M | GLN39 |
| M | CYS41 |
| M | VAL63 |
| M | CYS262 |
| M | VAL263 |
| M | ILE266 |
| M | ARG267 |
| site_id | AH1 |
| Number of Residues | 10 |
| Details | binding site for residue F3S M 504 |
| Chain | Residue |
| M | CYS187 |
| M | ILE192 |
| M | CYS208 |
| M | ARG209 |
| M | GLY210 |
| M | TYR211 |
| M | ARG212 |
| M | LYS213 |
| M | CYS214 |
| M | SER232 |
| site_id | AH2 |
| Number of Residues | 29 |
| Details | binding site for residue MD1 N 5801 |
| Chain | Residue |
| N | ASN70 |
| N | LYS236 |
| N | HIS273 |
| N | ASP275 |
| N | HIS531 |
| N | THR652 |
| N | ASN653 |
| N | VAL654 |
| N | ASN655 |
| N | ASN659 |
| N | LYS661 |
| N | THR680 |
| N | ASP681 |
| N | ILE682 |
| N | ASN698 |
| N | ASP734 |
| N | THR915 |
| N | LYS917 |
| N | VAL922 |
| N | HIS923 |
| N | SER924 |
| N | GLN925 |
| N | HIS1020 |
| N | GLN1057 |
| N | THR1060 |
| N | PRO1098 |
| N | MD15802 |
| N | MO5803 |
| N | HOH5901 |
| site_id | AH3 |
| Number of Residues | 31 |
| Details | binding site for residue MD1 N 5802 |
| Chain | Residue |
| N | ASP71 |
| N | LYS117 |
| N | ASP275 |
| N | THR305 |
| N | GLY306 |
| N | LYS307 |
| N | ASN308 |
| N | ASN312 |
| N | LYS313 |
| N | MET314 |
| N | ILE333 |
| N | PRO335 |
| N | GLU336 |
| N | ASN352 |
| N | ASN353 |
| N | ASP355 |
| N | GLY526 |
| N | GLU527 |
| N | GLY528 |
| N | VAL529 |
| N | TYR532 |
| N | GLY564 |
| N | PRO916 |
| N | LYS917 |
| N | SER918 |
| N | THR921 |
| N | HIS923 |
| N | LYS1099 |
| N | MD15801 |
| N | MO5803 |
| N | HOH5917 |
| site_id | AH4 |
| Number of Residues | 3 |
| Details | binding site for residue MO N 5803 |
| Chain | Residue |
| N | ASP275 |
| N | MD15801 |
| N | MD15802 |
| site_id | AH5 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 N 5804 |
| Chain | Residue |
| N | CYS67 |
| N | PRO69 |
| N | ASP71 |
| N | ALA74 |
| N | CYS75 |
| N | ILE77 |
| N | MET114 |
| N | CYS115 |
| N | GLY118 |
| site_id | AH6 |
| Number of Residues | 23 |
| Details | binding site for residue HEM O 401 |
| Chain | Residue |
| M | ARG189 |
| M | ARG209 |
| M | TYR211 |
| O | GLN84 |
| O | ALA135 |
| O | LEU136 |
| O | MET137 |
| O | ARG154 |
| O | MET155 |
| O | LEU164 |
| O | HIS166 |
| O | PHE241 |
| O | GLY242 |
| O | THR243 |
| O | LEU244 |
| O | ASN290 |
| O | MET291 |
| O | ALA292 |
| O | TRP294 |
| O | ASN302 |
| O | GLY303 |
| O | LYS305 |
| O | ILE307 |
| site_id | AH7 |
| Number of Residues | 5 |
| Details | binding site for residue CA O 402 |
| Chain | Residue |
| O | ASP117 |
| O | THR119 |
| O | ASN121 |
| O | ASP132 |
| O | ASN295 |
| site_id | AH8 |
| Number of Residues | 7 |
| Details | binding site for residue CA O 403 |
| Chain | Residue |
| O | ASP235 |
| O | GLN247 |
| O | HIS249 |
| O | ASP251 |
| O | ASP275 |
| O | ASP278 |
| O | HOH502 |
| site_id | AH9 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 P 501 |
| Chain | Residue |
| P | CYS45 |
| P | CYS235 |
| P | ILE236 |
| P | ALA237 |
| P | CYS238 |
| P | THR256 |
| P | CYS258 |
| site_id | AI1 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 P 502 |
| Chain | Residue |
| P | CYS175 |
| P | ASN176 |
| P | HIS177 |
| P | CYS178 |
| P | PRO181 |
| P | GLY182 |
| P | CYS183 |
| P | CYS218 |
| P | TYR220 |
| P | PRO223 |
| P | LYS234 |
| site_id | AI2 |
| Number of Residues | 12 |
| Details | binding site for residue SF4 P 503 |
| Chain | Residue |
| P | CYS35 |
| P | ILE36 |
| P | ALA37 |
| P | CYS38 |
| P | GLN39 |
| P | CYS41 |
| P | VAL63 |
| P | CYS262 |
| P | VAL263 |
| P | GLY264 |
| P | ILE266 |
| P | ARG267 |
| site_id | AI3 |
| Number of Residues | 11 |
| Details | binding site for residue F3S P 504 |
| Chain | Residue |
| P | CYS187 |
| P | ARG189 |
| P | ILE192 |
| P | CYS208 |
| P | ARG209 |
| P | GLY210 |
| P | TYR211 |
| P | ARG212 |
| P | LYS213 |
| P | CYS214 |
| P | SER232 |
| site_id | AI4 |
| Number of Residues | 30 |
| Details | binding site for residue MD1 Q 5801 |
| Chain | Residue |
| Q | ASN70 |
| Q | LYS236 |
| Q | HIS273 |
| Q | ASP275 |
| Q | HIS531 |
| Q | THR652 |
| Q | ASN653 |
| Q | VAL654 |
| Q | ASN655 |
| Q | ASN659 |
| Q | THR680 |
| Q | ASP681 |
| Q | ILE682 |
| Q | GLU683 |
| Q | THR685 |
| Q | ASN698 |
| Q | TRP700 |
| Q | ASP734 |
| Q | THR915 |
| Q | LYS917 |
| Q | VAL922 |
| Q | HIS923 |
| Q | SER924 |
| Q | GLN925 |
| Q | HIS1020 |
| Q | GLN1057 |
| Q | PRO1098 |
| Q | MD15802 |
| Q | MO5803 |
| Q | HOH5905 |
| site_id | AI5 |
| Number of Residues | 33 |
| Details | binding site for residue MD1 Q 5802 |
| Chain | Residue |
| Q | ASN70 |
| Q | ASP71 |
| Q | LYS117 |
| Q | ASP275 |
| Q | THR305 |
| Q | GLY306 |
| Q | LYS307 |
| Q | ASN308 |
| Q | GLU311 |
| Q | ASN312 |
| Q | LYS313 |
| Q | MET314 |
| Q | ILE333 |
| Q | THR334 |
| Q | PRO335 |
| Q | GLU336 |
| Q | ASN352 |
| Q | ASN353 |
| Q | ASP355 |
| Q | GLY526 |
| Q | GLU527 |
| Q | GLY528 |
| Q | VAL529 |
| Q | TYR532 |
| Q | GLY564 |
| Q | PRO916 |
| Q | LYS917 |
| Q | SER918 |
| Q | THR921 |
| Q | HIS923 |
| Q | LYS1099 |
| Q | MD15801 |
| Q | MO5803 |
| site_id | AI6 |
| Number of Residues | 4 |
| Details | binding site for residue MO Q 5803 |
| Chain | Residue |
| Q | ASP275 |
| Q | GLY564 |
| Q | MD15801 |
| Q | MD15802 |
| site_id | AI7 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 Q 5804 |
| Chain | Residue |
| Q | CYS67 |
| Q | PRO69 |
| Q | ASP71 |
| Q | CYS75 |
| Q | MET114 |
| Q | CYS115 |
| Q | GLY118 |
| site_id | AI8 |
| Number of Residues | 22 |
| Details | binding site for residue HEM R 401 |
| Chain | Residue |
| P | ARG189 |
| P | ARG209 |
| P | TYR211 |
| R | GLN84 |
| R | LYS86 |
| R | ALA135 |
| R | MET137 |
| R | ARG154 |
| R | MET155 |
| R | LEU164 |
| R | HIS166 |
| R | PHE241 |
| R | GLY242 |
| R | THR243 |
| R | LEU244 |
| R | ASN290 |
| R | MET291 |
| R | ALA292 |
| R | TRP294 |
| R | ASN302 |
| R | LYS305 |
| R | HOH501 |
| site_id | AI9 |
| Number of Residues | 6 |
| Details | binding site for residue CA R 402 |
| Chain | Residue |
| R | ASP235 |
| R | GLN247 |
| R | HIS249 |
| R | ASP251 |
| R | ASP275 |
| R | ASP278 |
| site_id | AJ1 |
| Number of Residues | 5 |
| Details | binding site for residue CA R 403 |
| Chain | Residue |
| R | ASP117 |
| R | THR119 |
| R | ASN121 |
| R | ASP132 |
| R | ASN295 |
| site_id | AJ2 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 S 501 |
| Chain | Residue |
| S | CYS45 |
| S | CYS235 |
| S | ILE236 |
| S | ALA237 |
| S | CYS238 |
| S | THR256 |
| S | CYS258 |
| site_id | AJ3 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 S 502 |
| Chain | Residue |
| S | CYS175 |
| S | ASN176 |
| S | HIS177 |
| S | CYS178 |
| S | PRO181 |
| S | GLY182 |
| S | CYS183 |
| S | CYS218 |
| S | TYR220 |
| S | PRO223 |
| S | LYS234 |
| site_id | AJ4 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 S 503 |
| Chain | Residue |
| S | CYS35 |
| S | ILE36 |
| S | ALA37 |
| S | CYS38 |
| S | GLN39 |
| S | CYS41 |
| S | VAL63 |
| S | CYS262 |
| S | VAL263 |
| S | ILE266 |
| S | ARG267 |
| site_id | AJ5 |
| Number of Residues | 10 |
| Details | binding site for residue F3S S 504 |
| Chain | Residue |
| S | CYS187 |
| S | ILE192 |
| S | CYS208 |
| S | ARG209 |
| S | GLY210 |
| S | TYR211 |
| S | ARG212 |
| S | LYS213 |
| S | CYS214 |
| S | SER232 |
| site_id | AJ6 |
| Number of Residues | 34 |
| Details | binding site for residue MD1 T 5801 |
| Chain | Residue |
| T | ASN70 |
| T | ARG124 |
| T | LYS236 |
| T | HIS273 |
| T | ASP275 |
| T | HIS531 |
| T | THR652 |
| T | ASN653 |
| T | VAL654 |
| T | ASN655 |
| T | ASN659 |
| T | LYS661 |
| T | THR680 |
| T | ASP681 |
| T | ILE682 |
| T | THR685 |
| T | ALA697 |
| T | ASN698 |
| T | TRP700 |
| T | ASP734 |
| T | THR915 |
| T | LYS917 |
| T | VAL922 |
| T | HIS923 |
| T | SER924 |
| T | GLN925 |
| T | HIS1020 |
| T | GLN1057 |
| T | THR1060 |
| T | PRO1098 |
| T | MD15802 |
| T | MO5803 |
| T | HOH5911 |
| T | HOH5919 |
| site_id | AJ7 |
| Number of Residues | 31 |
| Details | binding site for residue MD1 T 5802 |
| Chain | Residue |
| T | ASP71 |
| T | LYS117 |
| T | ASP275 |
| T | THR305 |
| T | GLY306 |
| T | LYS307 |
| T | ASN308 |
| T | GLU311 |
| T | ASN312 |
| T | LYS313 |
| T | ILE333 |
| T | PRO335 |
| T | GLU336 |
| T | ASN352 |
| T | ASN353 |
| T | ASP355 |
| T | GLY526 |
| T | GLU527 |
| T | GLY528 |
| T | VAL529 |
| T | TYR532 |
| T | ALA563 |
| T | GLY564 |
| T | PRO916 |
| T | LYS917 |
| T | SER918 |
| T | THR921 |
| T | HIS923 |
| T | LYS1099 |
| T | MD15801 |
| T | MO5803 |
| site_id | AJ8 |
| Number of Residues | 3 |
| Details | binding site for residue MO T 5803 |
| Chain | Residue |
| T | ASP275 |
| T | MD15801 |
| T | MD15802 |
| site_id | AJ9 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 T 5804 |
| Chain | Residue |
| T | CYS67 |
| T | PRO69 |
| T | ASP71 |
| T | ALA74 |
| T | CYS75 |
| T | MET114 |
| T | CYS115 |
| T | GLY118 |
| site_id | AK1 |
| Number of Residues | 22 |
| Details | binding site for residue HEM U 401 |
| Chain | Residue |
| S | ARG189 |
| S | ARG209 |
| S | TYR211 |
| U | GLN84 |
| U | LEU136 |
| U | MET137 |
| U | ARG154 |
| U | MET155 |
| U | LEU164 |
| U | HIS166 |
| U | PHE241 |
| U | GLY242 |
| U | THR243 |
| U | LEU244 |
| U | ASN290 |
| U | MET291 |
| U | ALA292 |
| U | TRP294 |
| U | ARG301 |
| U | ASN302 |
| U | LYS305 |
| U | ILE307 |
| site_id | AK2 |
| Number of Residues | 5 |
| Details | binding site for residue CA U 402 |
| Chain | Residue |
| U | ASP117 |
| U | THR119 |
| U | ASN121 |
| U | ASP132 |
| U | ASN295 |
| site_id | AK3 |
| Number of Residues | 6 |
| Details | binding site for residue CA U 403 |
| Chain | Residue |
| U | ASP235 |
| U | GLN247 |
| U | HIS249 |
| U | ASP251 |
| U | ASP275 |
| U | ASP278 |
| site_id | AK4 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 V 501 |
| Chain | Residue |
| V | CYS45 |
| V | TRP49 |
| V | TRP60 |
| V | ASN61 |
| V | CYS235 |
| V | ILE236 |
| V | ALA237 |
| V | CYS238 |
| V | THR256 |
| V | CYS258 |
| site_id | AK5 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 V 502 |
| Chain | Residue |
| V | CYS175 |
| V | ASN176 |
| V | HIS177 |
| V | CYS178 |
| V | PRO181 |
| V | GLY182 |
| V | CYS183 |
| V | CYS218 |
| V | TYR220 |
| V | LYS222 |
| V | PRO223 |
| site_id | AK6 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 V 503 |
| Chain | Residue |
| V | ARG267 |
| V | CYS35 |
| V | ILE36 |
| V | ALA37 |
| V | CYS38 |
| V | GLN39 |
| V | CYS41 |
| V | VAL63 |
| V | CYS262 |
| V | VAL263 |
| V | ILE266 |
| site_id | AK7 |
| Number of Residues | 11 |
| Details | binding site for residue F3S V 504 |
| Chain | Residue |
| V | CYS187 |
| V | ALA191 |
| V | ILE192 |
| V | ILE203 |
| V | CYS208 |
| V | GLY210 |
| V | TYR211 |
| V | ARG212 |
| V | LYS213 |
| V | CYS214 |
| V | SER232 |
| site_id | AK8 |
| Number of Residues | 31 |
| Details | binding site for residue MD1 W 5801 |
| Chain | Residue |
| W | ASN70 |
| W | ARG124 |
| W | LYS236 |
| W | HIS273 |
| W | ASP275 |
| W | HIS531 |
| W | THR652 |
| W | ASN653 |
| W | VAL654 |
| W | ASN655 |
| W | ASN659 |
| W | LYS661 |
| W | THR680 |
| W | ASP681 |
| W | ILE682 |
| W | THR685 |
| W | ASN698 |
| W | TRP700 |
| W | ASP734 |
| W | THR915 |
| W | LYS917 |
| W | VAL922 |
| W | HIS923 |
| W | SER924 |
| W | GLN925 |
| W | HIS1020 |
| W | GLN1057 |
| W | THR1060 |
| W | PRO1098 |
| W | MD15802 |
| W | MO5803 |
| site_id | AK9 |
| Number of Residues | 30 |
| Details | binding site for residue MD1 W 5802 |
| Chain | Residue |
| W | LYS117 |
| W | ASP275 |
| W | THR305 |
| W | GLY306 |
| W | LYS307 |
| W | ASN308 |
| W | GLU311 |
| W | ASN312 |
| W | LYS313 |
| W | MET314 |
| W | ILE333 |
| W | PRO335 |
| W | GLU336 |
| W | ASN352 |
| W | ASN353 |
| W | ASP355 |
| W | GLY526 |
| W | GLU527 |
| W | GLY528 |
| W | TYR532 |
| W | ALA563 |
| W | GLY564 |
| W | PRO916 |
| W | LYS917 |
| W | SER918 |
| W | THR921 |
| W | HIS923 |
| W | LYS1099 |
| W | MD15801 |
| W | MO5803 |
| site_id | AL1 |
| Number of Residues | 3 |
| Details | binding site for residue MO W 5803 |
| Chain | Residue |
| W | ASP275 |
| W | MD15801 |
| W | MD15802 |
| site_id | AL2 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 W 5804 |
| Chain | Residue |
| W | CYS67 |
| W | ASP71 |
| W | CYS75 |
| W | MET114 |
| W | CYS115 |
| W | GLY118 |
| W | PRO315 |
| site_id | AL3 |
| Number of Residues | 23 |
| Details | binding site for residue HEM X 401 |
| Chain | Residue |
| V | ARG189 |
| V | ARG209 |
| V | TYR211 |
| X | GLN84 |
| X | ALA135 |
| X | MET137 |
| X | PRO153 |
| X | ARG154 |
| X | MET155 |
| X | LEU164 |
| X | HIS166 |
| X | PHE241 |
| X | GLY242 |
| X | THR243 |
| X | LEU244 |
| X | ASN290 |
| X | MET291 |
| X | ALA292 |
| X | TRP294 |
| X | ASN302 |
| X | LYS305 |
| X | ILE307 |
| X | SER308 |
| site_id | AL4 |
| Number of Residues | 6 |
| Details | binding site for residue CA X 402 |
| Chain | Residue |
| X | ASP235 |
| X | GLN247 |
| X | HIS249 |
| X | ASP251 |
| X | ASP275 |
| X | ASP278 |
| site_id | AL5 |
| Number of Residues | 5 |
| Details | binding site for residue CA X 403 |
| Chain | Residue |
| X | ASP117 |
| X | THR119 |
| X | ASN121 |
| X | ASP132 |
| X | ASN295 |
| site_id | AL6 |
| Number of Residues | 40 |
| Details | binding site for residues MD1 E 5801 and MD1 E 5802 |
| Chain | Residue |
| E | ASN70 |
| E | HIS273 |
| E | ASP275 |
| E | THR305 |
| E | GLY306 |
| E | ASN308 |
| E | GLU311 |
| E | ASN312 |
| E | ILE333 |
| E | PRO335 |
| E | SER338 |
| E | ASN353 |
| E | GLY526 |
| E | GLU527 |
| E | GLY528 |
| E | HIS531 |
| E | TYR532 |
| E | ALA563 |
| E | GLY564 |
| E | THR652 |
| E | ASN653 |
| E | VAL654 |
| E | ASN655 |
| E | THR680 |
| E | ALA697 |
| E | ASN698 |
| E | TRP700 |
| E | THR915 |
| E | PRO916 |
| E | LYS917 |
| E | THR921 |
| E | VAL922 |
| E | HIS923 |
| E | SER924 |
| E | GLN925 |
| E | HIS1020 |
| E | GLN1057 |
| E | PRO1098 |
| E | MO5803 |
| E | HOH5902 |
