7AOT
The Fk1 domain of FKBP51 in complex with (2R,5S,12R)-12-cyclohexyl-2-[2-(3,4-dimethoxyphenyl)ethyl]-3,19-dioxa-10,13,16-triazatricyclo[18.3.1.0-5,10]tetracosa- 1(24),20,22-triene-4,11,14,17-tetrone
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue RTQ A 201 |
| Chain | Residue |
| A | LYS28 |
| A | ILE87 |
| A | TRP90 |
| A | ALA112 |
| A | TYR113 |
| A | LYS121 |
| A | PHE130 |
| A | HOH312 |
| A | HOH332 |
| A | HOH380 |
| A | HOH388 |
| A | LYS29 |
| A | HOH412 |
| A | HOH423 |
| A | ASP30 |
| A | ARG31 |
| A | TYR57 |
| A | PHE77 |
| A | GLY84 |
| A | GLN85 |
| A | VAL86 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 88 |
| Details | Domain: {"description":"PPIase FKBP-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00277","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"28147277","evidenceCode":"ECO:0000269"}]} |
