7ALJ

Structure of Drosophila Notch EGF domains 11-13

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CvNtpgsYrCnC

Chain	Residue	Details
A	CYS465-CYS476
A	CYS503-CYS514
A	CYS541-CYS552

---

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CnCsqGftGPrC

Chain	Residue	Details
A	CYS474-CYS485
A	CYS512-CYS523
A	CYS550-CYS561

---

site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CnCsqGFtgpr....C

Chain	Residue	Details
A	CYS474-CYS485
A	CYS512-CYS523
A	CYS550-CYS561

---

site_id	PS01187
Number of Residues	26
Details	EGF_CA Calcium-binding EGF-like domain signature. DiDECdqgsp.........Cehngi..CvNtpgsYrC

Chain	Residue	Details
A	ASP449-CYS474
A	ASN488-CYS512
A	ASP526-CYS550

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Domain: {"description":"EGF-like 12; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Domain: {"description":"EGF-like 13; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GlcNAc...) threonine","evidences":[{"source":"PubMed","id":"27268051","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (Glc...) serine","evidences":[{"source":"PubMed","id":"27268051","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (Fuc...) serine","evidences":[{"source":"PubMed","id":"27268051","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---