7AE2

Crystal structure of HEPN(H107A-Y109F) toxin in complex with MNT antitoxin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004540	molecular_function	RNA nuclease activity
A	0110001	cellular_component	toxin-antitoxin complex
B	0070733	molecular_function	AMPylase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Motif: {"description":"RX(4)HXY motif","evidences":[{"source":"PubMed","id":"33290744","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Motif: {"description":"Y-loop","evidences":[{"source":"PubMed","id":"33290744","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {"evidences":[{"source":"PubMed","id":"33290744","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"O-di-AMP-tyrosine","evidences":[{"source":"PubMed","id":"33290744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7AE6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8ECH7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---