7A0Y

Structure of dimeric sodium proton antiporter NhaA K300R variant, at pH 8.2, crystallized with chimeric Fab antibodies

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006814	biological_process	sodium ion transport
A	0006885	biological_process	regulation of pH
A	0015081	molecular_function	sodium ion transmembrane transporter activity
A	0015297	molecular_function	antiporter activity
A	0015385	molecular_function	sodium:proton antiporter activity
A	0016020	cellular_component	membrane
A	0035725	biological_process	sodium ion transmembrane transport
A	0055085	biological_process	transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006814	biological_process	sodium ion transport
B	0006885	biological_process	regulation of pH
B	0015081	molecular_function	sodium ion transmembrane transporter activity
B	0015297	molecular_function	antiporter activity
B	0015385	molecular_function	sodium:proton antiporter activity
B	0016020	cellular_component	membrane
B	0035725	biological_process	sodium ion transmembrane transport
B	0055085	biological_process	transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
C	TYR203-HIS209
D	TYR188-HIS194

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	440
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_01844

Chain	Residue	Details
A	GLY14-THR34
A	ILE328-LEU348
A	TRP360-LEU380
B	GLY14-THR34
B	MET59-VAL79
B	ALA95-PHE115
B	GLY125-GLY145
B	ILE154-PHE174
B	LEU179-LEU199
B	VAL219-LEU239
B	VAL254-VAL274
A	MET59-VAL79
B	ILE292-LEU312
B	ILE328-LEU348
B	TRP360-LEU380
A	ALA95-PHE115
A	GLY125-GLY145
A	ILE154-PHE174
A	LEU179-LEU199
A	VAL219-LEU239
A	VAL254-VAL274
A	ILE292-LEU312

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