6ZSL
Crystal structure of the SARS-CoV-2 helicase at 1.94 Angstrom resolution
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 701 |
| Chain | Residue |
| B | CYS16 |
| B | CYS19 |
| B | HIS33 |
| B | HIS39 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 702 |
| Chain | Residue |
| B | CYS5 |
| B | CYS8 |
| B | CYS26 |
| B | CYS29 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 703 |
| Chain | Residue |
| B | CYS55 |
| B | CYS72 |
| B | HIS75 |
| B | CYS50 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 B 704 |
| Chain | Residue |
| B | GLY285 |
| B | THR286 |
| B | GLY287 |
| B | LYS288 |
| B | SER289 |
| B | ARG443 |
| B | PO4705 |
| B | HOH820 |
| B | HOH932 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 705 |
| Chain | Residue |
| B | PRO284 |
| B | LYS288 |
| B | GLN404 |
| B | ARG443 |
| B | GLY538 |
| B | ARG567 |
| B | PO4704 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 701 |
| Chain | Residue |
| A | CYS50 |
| A | CYS55 |
| A | CYS72 |
| A | HIS75 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 702 |
| Chain | Residue |
| A | CYS16 |
| A | CYS19 |
| A | HIS33 |
| A | HIS39 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 703 |
| Chain | Residue |
| A | CYS5 |
| A | CYS8 |
| A | CYS26 |
| A | CYS29 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 704 |
| Chain | Residue |
| A | GLY285 |
| A | THR286 |
| A | GLY287 |
| A | LYS288 |
| A | SER289 |
| A | ARG443 |
| A | PO4705 |
| A | HOH802 |
| A | HOH869 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 705 |
| Chain | Residue |
| A | PRO284 |
| A | LYS288 |
| A | GLN404 |
| A | ARG443 |
| A | GLY538 |
| A | ARG567 |
| A | PO4704 |
| A | HOH802 |
| A | HOH825 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 8","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00986","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33232691","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CYQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00990","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 181 |
| Details | Domain: {"description":"(+)RNA virus helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00990","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
