6ZNW
Methanosaeta concilii ATP citrate lyase (D541A mutant) in complex with (3S)-citryl-CoA.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003878 | molecular_function | ATP citrate synthase activity |
| A | 0004775 | molecular_function | succinate-CoA ligase (ADP-forming) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006104 | biological_process | succinyl-CoA metabolic process |
| A | 0042709 | cellular_component | succinate-CoA ligase complex |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003878 | molecular_function | ATP citrate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue FLC A 501 |
| Chain | Residue |
| A | SER306 |
| A | HOH603 |
| A | HOH610 |
| B | HOH856 |
| A | GLY307 |
| A | ALA343 |
| A | ASN344 |
| A | PHE345 |
| A | THR346 |
| A | ARG377 |
| A | MG502 |
| A | PO4503 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | SER306 |
| A | FLC501 |
| A | PO4503 |
| A | HOH610 |
| A | HOH611 |
| B | HOH856 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue PO4 A 503 |
| Chain | Residue |
| A | GLY279 |
| A | GLY280 |
| A | GLY281 |
| A | SER306 |
| A | FLC501 |
| A | MG502 |
| A | HOH609 |
| A | HOH611 |
| B | SER178 |
| B | GLY179 |
| B | GLY180 |
| B | HIS275 |
| B | HOH856 |
| site_id | AC4 |
| Number of Residues | 30 |
| Details | binding site for residue Q5B B 701 |
| Chain | Residue |
| B | SER49 |
| B | HIS415 |
| B | VAL419 |
| B | PRO448 |
| B | ARG449 |
| B | PHE450 |
| B | GLY451 |
| B | ALA453 |
| B | ASN484 |
| B | ILE485 |
| B | GLY487 |
| B | ILE488 |
| B | GLY489 |
| B | HIS490 |
| B | ARG501 |
| B | LYS533 |
| B | LEU536 |
| B | ASN539 |
| B | ARG580 |
| B | ARG597 |
| B | LEU598 |
| B | ARG600 |
| B | HOH811 |
| B | HOH820 |
| B | HOH835 |
| B | HOH841 |
| B | HOH851 |
| B | HOH901 |
| B | HOH922 |
| B | HOH940 |
