6ZK2
Plant nucleoside hydrolase - ZmNRh2b in complex with forodesine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006152 | biological_process | purine nucleoside catabolic process |
| A | 0008477 | molecular_function | purine nucleosidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0042454 | biological_process | ribonucleoside catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0046982 | molecular_function | protein heterodimerization activity |
| A | 0047724 | molecular_function | inosine nucleosidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006152 | biological_process | purine nucleoside catabolic process |
| B | 0008477 | molecular_function | purine nucleosidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| B | 0042454 | biological_process | ribonucleoside catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0046982 | molecular_function | protein heterodimerization activity |
| B | 0047724 | molecular_function | inosine nucleosidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006152 | biological_process | purine nucleoside catabolic process |
| C | 0008477 | molecular_function | purine nucleosidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| C | 0042454 | biological_process | ribonucleoside catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0046982 | molecular_function | protein heterodimerization activity |
| C | 0047724 | molecular_function | inosine nucleosidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006152 | biological_process | purine nucleoside catabolic process |
| D | 0008477 | molecular_function | purine nucleosidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| D | 0042454 | biological_process | ribonucleoside catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0046982 | molecular_function | protein heterodimerization activity |
| D | 0047724 | molecular_function | inosine nucleosidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | ASP18 |
| A | ASP23 |
| A | ASN47 |
| A | LEU133 |
| A | ASP250 |
| A | IMH402 |
| A | HOH501 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for residue IMH A 402 |
| Chain | Residue |
| A | ASN47 |
| A | VAL90 |
| A | HIS91 |
| A | LEU133 |
| A | LEU159 |
| A | ASN168 |
| A | GLU174 |
| A | ALA175 |
| A | ASN176 |
| A | TYR233 |
| A | TRP236 |
| A | HIS249 |
| A | ASP250 |
| A | CA401 |
| A | HOH501 |
| A | HOH518 |
| A | HOH536 |
| A | HOH550 |
| A | HOH554 |
| A | HOH578 |
| A | ASP22 |
| A | ASP23 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 403 |
| Chain | Residue |
| A | LYS51 |
| A | THR54 |
| A | HOH556 |
| D | SER122 |
| D | GLU123 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 404 |
| Chain | Residue |
| A | LYS239 |
| B | LYS290 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 405 |
| Chain | Residue |
| A | LYS80 |
| A | HIS178 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | GLY46 |
| A | ARG85 |
| A | ALA87 |
| A | HOH550 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | ASP185 |
| A | THR189 |
| A | TYR300 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | PHE163 |
| A | ASN200 |
| A | TRP307 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | ASN170 |
| B | SER293 |
| B | ASN295 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | ALA224 |
| A | PHE225 |
| B | HOH520 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 401 |
| Chain | Residue |
| B | ASP18 |
| B | ASP23 |
| B | ASN47 |
| B | LEU133 |
| B | ASP250 |
| B | IMH402 |
| B | HOH506 |
| site_id | AD3 |
| Number of Residues | 19 |
| Details | binding site for residue IMH B 402 |
| Chain | Residue |
| B | ASP22 |
| B | ASP23 |
| B | ASN47 |
| B | HIS91 |
| B | LEU133 |
| B | LEU159 |
| B | ASN168 |
| B | GLU174 |
| B | ALA175 |
| B | ASN176 |
| B | TYR233 |
| B | TRP236 |
| B | HIS249 |
| B | ASP250 |
| B | CA401 |
| B | HOH506 |
| B | HOH537 |
| B | HOH546 |
| B | HOH553 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 403 |
| Chain | Residue |
| B | ASP88 |
| B | SER93 |
| B | ASN98 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 404 |
| Chain | Residue |
| B | SER75 |
| B | GLU77 |
| B | PRO78 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 405 |
| Chain | Residue |
| A | SER293 |
| A | GLU294 |
| A | ASN295 |
| B | VAL169 |
| B | ASN170 |
| B | HIS178 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue PEG B 406 |
| Chain | Residue |
| B | ARG10 |
| B | ALA30 |
| B | PHE31 |
| B | ALA33 |
| B | VAL36 |
| B | ILE38 |
| B | VAL69 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue PGE B 407 |
| Chain | Residue |
| A | ALA238 |
| A | LYS239 |
| A | SER240 |
| B | GLY287 |
| B | LEU288 |
| B | LYS290 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 408 |
| Chain | Residue |
| B | PHE163 |
| B | ASN200 |
| B | TRP307 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 409 |
| Chain | Residue |
| B | LYS155 |
| B | ASP193 |
| B | SER304 |
| B | HOH542 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 410 |
| Chain | Residue |
| B | LYS289 |
| B | LYS290 |
| B | TRP291 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 411 |
| Chain | Residue |
| B | GLU261 |
| B | THR308 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 401 |
| Chain | Residue |
| C | ASP18 |
| C | ASP23 |
| C | ASN47 |
| C | LEU133 |
| C | ASP250 |
| C | IMH402 |
| C | HOH501 |
| site_id | AE5 |
| Number of Residues | 22 |
| Details | binding site for residue IMH C 402 |
| Chain | Residue |
| C | ASP22 |
| C | ASP23 |
| C | ASN47 |
| C | VAL90 |
| C | HIS91 |
| C | LEU133 |
| C | LEU159 |
| C | ASN168 |
| C | GLU174 |
| C | ALA175 |
| C | ASN176 |
| C | TYR233 |
| C | TRP236 |
| C | HIS249 |
| C | ASP250 |
| C | CA401 |
| C | HOH501 |
| C | HOH502 |
| C | HOH505 |
| C | HOH525 |
| C | HOH537 |
| C | HOH541 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue DMS C 403 |
| Chain | Residue |
| C | ASP185 |
| C | THR189 |
| site_id | AE7 |
| Number of Residues | 1 |
| Details | binding site for residue DMS C 404 |
| Chain | Residue |
| C | HIS244 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 405 |
| Chain | Residue |
| C | PHE163 |
| C | ASN200 |
| C | ILE201 |
| C | TRP307 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue PEG C 406 |
| Chain | Residue |
| C | LYS239 |
| C | SER240 |
| C | GLY242 |
| D | GLY287 |
| D | LEU288 |
| D | LYS290 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 407 |
| Chain | Residue |
| C | ASP88 |
| C | SER93 |
| C | ASN98 |
| C | PHE232 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 408 |
| Chain | Residue |
| C | GLY299 |
| C | TYR300 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 409 |
| Chain | Residue |
| B | HOH505 |
| C | ASN170 |
| D | PRO296 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 401 |
| Chain | Residue |
| D | ASP18 |
| D | ASP23 |
| D | ASN47 |
| D | LEU133 |
| D | ASP250 |
| D | IMH402 |
| site_id | AF5 |
| Number of Residues | 20 |
| Details | binding site for residue IMH D 402 |
| Chain | Residue |
| D | ASP22 |
| D | ASP23 |
| D | ASN47 |
| D | VAL90 |
| D | HIS91 |
| D | LEU133 |
| D | LEU159 |
| D | ASN168 |
| D | GLU174 |
| D | ALA175 |
| D | ASN176 |
| D | TYR233 |
| D | TRP236 |
| D | HIS249 |
| D | ASP250 |
| D | CA401 |
| D | DMS405 |
| D | HOH519 |
| D | HOH525 |
| D | HOH536 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue DMS D 403 |
| Chain | Residue |
| D | LYS290 |
| D | TRP291 |
| D | ASN292 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 404 |
| Chain | Residue |
| B | HIS76 |
| D | ASP185 |
| D | THR189 |
| D | TYR300 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 405 |
| Chain | Residue |
| D | GLY46 |
| D | ARG85 |
| D | ALA87 |
| D | PHE89 |
| D | IMH402 |
| site_id | AF9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 406 |
| Chain | Residue |
| D | ASN200 |
| D | TRP307 |
| site_id | AG1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO D 407 |
| Chain | Residue |
| D | HIS76 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 408 |
| Chain | Residue |
| D | LYS80 |
| D | GLY81 |
| D | LYS83 |
