6ZEF
Structure of PP1(7-300) bound to Phactr1 (516-580) at pH 5.25
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | GLU56 |
| A | GLU116 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | PRO50 |
| A | LEU52 |
| A | GLU54 |
| A | ARG187 |
| D | ARG521 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | GLU116 |
| A | HOH527 |
| A | PRO50 |
| A | GLU54 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | PRO82 |
| A | TYR110 |
| A | TYR114 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | ILE189 |
| A | ARG191 |
| D | LYS517 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 406 |
| Chain | Residue |
| A | ASP64 |
| A | ASP92 |
| A | ASN124 |
| A | HIS173 |
| A | HIS248 |
| A | HOH556 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MN A 407 |
| Chain | Residue |
| A | TYR272 |
| A | HOH556 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| B | LEU55 |
| B | GLU56 |
| B | PRO59 |
| B | ASN86 |
| B | GLU116 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | ARG132 |
| B | ILE133 |
| B | ASP138 |
| B | HOH513 |
| D | TRP542 |
| D | LEU545 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | PRO59 |
| B | LEU59 |
| B | LYS60 |
| B | SER85 |
| B | ASN86 |
| B | SER284 |
| B | VAL285 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue MN B 404 |
| Chain | Residue |
| B | ASP64 |
| B | ASP92 |
| B | ASN124 |
| B | HIS173 |
| B | HIS248 |
| B | HOH571 |
| B | HOH591 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue MN B 405 |
| Chain | Residue |
| B | HIS66 |
| B | TYR272 |
| B | HOH591 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 601 |
| Chain | Residue |
| A | ARG132 |
| C | GLU556 |
| C | HOH701 |
Functional Information from PROSITE/UniProt
| site_id | PS00125 |
| Number of Residues | 6 |
| Details | SER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE |
| Chain | Residue | Details |
| A | LEU121-GLU126 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P36873","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30100357","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35830882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35831509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36175670","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39446389","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6CZO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TVF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7UPI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8SW5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
