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6ZCE

Structure of a yeast ABCE1-bound 43S pre-initiation complex

Functional Information from GO Data
ChainGOidnamespacecontents
B0000028biological_processribosomal small subunit assembly
B0000054biological_processribosomal subunit export from nucleus
B0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B0000461biological_processendonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B0002181biological_processcytoplasmic translation
B0003735molecular_functionstructural constituent of ribosome
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005840cellular_componentribosome
B0006364biological_processrRNA processing
B0006412biological_processtranslation
B0010494cellular_componentcytoplasmic stress granule
B0015935cellular_componentsmall ribosomal subunit
B0022627cellular_componentcytosolic small ribosomal subunit
B0030686cellular_component90S preribosome
B0042254biological_processribosome biogenesis
B1990904cellular_componentribonucleoprotein complex
C0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C0002181biological_processcytoplasmic translation
C0003735molecular_functionstructural constituent of ribosome
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005840cellular_componentribosome
C0006412biological_processtranslation
C0022627cellular_componentcytosolic small ribosomal subunit
C0030686cellular_component90S preribosome
C1990904cellular_componentribonucleoprotein complex
D0000054biological_processribosomal subunit export from nucleus
D0002181biological_processcytoplasmic translation
D0003723molecular_functionRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005730cellular_componentnucleolus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005840cellular_componentribosome
D0006364biological_processrRNA processing
D0006412biological_processtranslation
D0015935cellular_componentsmall ribosomal subunit
D0022627cellular_componentcytosolic small ribosomal subunit
D0032040cellular_componentsmall-subunit processome
D0042254biological_processribosome biogenesis
D0045903biological_processpositive regulation of translational fidelity
D0070181molecular_functionsmall ribosomal subunit rRNA binding
D1990904cellular_componentribonucleoprotein complex
E0000054biological_processribosomal subunit export from nucleus
E0000056biological_processribosomal small subunit export from nucleus
E0002181biological_processcytoplasmic translation
E0003723molecular_functionRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0003906molecular_functionDNA-(apurinic or apyrimidinic site) endonuclease activity
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0005840cellular_componentribosome
E0006412biological_processtranslation
E0015935cellular_componentsmall ribosomal subunit
E0022626cellular_componentcytosolic ribosome
E0022627cellular_componentcytosolic small ribosomal subunit
E0030686cellular_component90S preribosome
E0030688cellular_componentpreribosome, small subunit precursor
E0070651biological_processnonfunctional rRNA decay
E1990145biological_processmaintenance of translational fidelity
E1990904cellular_componentribonucleoprotein complex
F0002181biological_processcytoplasmic translation
F0003723molecular_functionRNA binding
F0003735molecular_functionstructural constituent of ribosome
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0005840cellular_componentribosome
F0006412biological_processtranslation
F0019843molecular_functionrRNA binding
F0022627cellular_componentcytosolic small ribosomal subunit
F0030686cellular_component90S preribosome
F0032991cellular_componentprotein-containing complex
F0043232cellular_componentintracellular non-membrane-bounded organelle
F1990904cellular_componentribonucleoprotein complex
G0000028biological_processribosomal small subunit assembly
G0000054biological_processribosomal subunit export from nucleus
G0002181biological_processcytoplasmic translation
G0003723molecular_functionRNA binding
G0003729molecular_functionmRNA binding
G0003735molecular_functionstructural constituent of ribosome
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0005840cellular_componentribosome
G0006412biological_processtranslation
G0006450biological_processregulation of translational fidelity
G0015935cellular_componentsmall ribosomal subunit
G0019843molecular_functionrRNA binding
G0022627cellular_componentcytosolic small ribosomal subunit
G0030490biological_processmaturation of SSU-rRNA
G0030686cellular_component90S preribosome
G1990904cellular_componentribonucleoprotein complex
H0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0003735molecular_functionstructural constituent of ribosome
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005730cellular_componentnucleolus
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0005840cellular_componentribosome
H0006364biological_processrRNA processing
H0006412biological_processtranslation
H0022627cellular_componentcytosolic small ribosomal subunit
H0030686cellular_component90S preribosome
H0032040cellular_componentsmall-subunit processome
H0042254biological_processribosome biogenesis
H1990904cellular_componentribonucleoprotein complex
I0002181biological_processcytoplasmic translation
I0003735molecular_functionstructural constituent of ribosome
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005730cellular_componentnucleolus
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0005840cellular_componentribosome
I0006364biological_processrRNA processing
I0006412biological_processtranslation
I0022627cellular_componentcytosolic small ribosomal subunit
I0030686cellular_component90S preribosome
I0032040cellular_componentsmall-subunit processome
I0042254biological_processribosome biogenesis
I0042274biological_processribosomal small subunit biogenesis
I1990904cellular_componentribonucleoprotein complex
J0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J0003735molecular_functionstructural constituent of ribosome
J0005737cellular_componentcytoplasm
J0005829cellular_componentcytosol
J0005840cellular_componentribosome
J0006412biological_processtranslation
J0022627cellular_componentcytosolic small ribosomal subunit
J0030686cellular_component90S preribosome
J1990904cellular_componentribonucleoprotein complex
K0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K0003723molecular_functionRNA binding
K0003735molecular_functionstructural constituent of ribosome
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005654cellular_componentnucleoplasm
K0005730cellular_componentnucleolus
K0005737cellular_componentcytoplasm
K0005829cellular_componentcytosol
K0005840cellular_componentribosome
K0006364biological_processrRNA processing
K0006412biological_processtranslation
K0015935cellular_componentsmall ribosomal subunit
K0019843molecular_functionrRNA binding
K0022627cellular_componentcytosolic small ribosomal subunit
K0030686cellular_component90S preribosome
K0032040cellular_componentsmall-subunit processome
K0042254biological_processribosome biogenesis
K0042274biological_processribosomal small subunit biogenesis
K0043226cellular_componentorganelle
K1990904cellular_componentribonucleoprotein complex
L0000054biological_processribosomal subunit export from nucleus
L0002181biological_processcytoplasmic translation
L0003723molecular_functionRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0005515molecular_functionprotein binding
L0005737cellular_componentcytoplasm
L0005829cellular_componentcytosol
L0005840cellular_componentribosome
L0022627cellular_componentcytosolic small ribosomal subunit
L0034198biological_processcellular response to amino acid starvation
L0045860biological_processpositive regulation of protein kinase activity
L1990904cellular_componentribonucleoprotein complex
M0000028biological_processribosomal small subunit assembly
M0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M0003735molecular_functionstructural constituent of ribosome
M0005737cellular_componentcytoplasm
M0005829cellular_componentcytosol
M0005840cellular_componentribosome
M0006412biological_processtranslation
M0019843molecular_functionrRNA binding
M0022627cellular_componentcytosolic small ribosomal subunit
M0030686cellular_component90S preribosome
M1990904cellular_componentribonucleoprotein complex
N0000028biological_processribosomal small subunit assembly
N0002181biological_processcytoplasmic translation
N0003735molecular_functionstructural constituent of ribosome
N0005737cellular_componentcytoplasm
N0005829cellular_componentcytosol
N0005840cellular_componentribosome
N0006364biological_processrRNA processing
N0006412biological_processtranslation
N0022627cellular_componentcytosolic small ribosomal subunit
N0030490biological_processmaturation of SSU-rRNA
N0042274biological_processribosomal small subunit biogenesis
N1990145biological_processmaintenance of translational fidelity
N1990904cellular_componentribonucleoprotein complex
O0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
O0002181biological_processcytoplasmic translation
O0003735molecular_functionstructural constituent of ribosome
O0005730cellular_componentnucleolus
O0005737cellular_componentcytoplasm
O0005829cellular_componentcytosol
O0005840cellular_componentribosome
O0006412biological_processtranslation
O0022627cellular_componentcytosolic small ribosomal subunit
O0030686cellular_component90S preribosome
O0070181molecular_functionsmall ribosomal subunit rRNA binding
O1990904cellular_componentribonucleoprotein complex
P0000028biological_processribosomal small subunit assembly
P0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P0002181biological_processcytoplasmic translation
P0003729molecular_functionmRNA binding
P0003735molecular_functionstructural constituent of ribosome
P0005634cellular_componentnucleus
P0005654cellular_componentnucleoplasm
P0005730cellular_componentnucleolus
P0005737cellular_componentcytoplasm
P0005829cellular_componentcytosol
P0005840cellular_componentribosome
P0006364biological_processrRNA processing
P0006412biological_processtranslation
P0022627cellular_componentcytosolic small ribosomal subunit
P0030686cellular_component90S preribosome
P0032040cellular_componentsmall-subunit processome
P0042254biological_processribosome biogenesis
P1990904cellular_componentribonucleoprotein complex
Q0000028biological_processribosomal small subunit assembly
Q0000054biological_processribosomal subunit export from nucleus
Q0002181biological_processcytoplasmic translation
Q0003723molecular_functionRNA binding
Q0003735molecular_functionstructural constituent of ribosome
Q0005737cellular_componentcytoplasm
Q0005829cellular_componentcytosol
Q0005840cellular_componentribosome
Q0006412biological_processtranslation
Q0015935cellular_componentsmall ribosomal subunit
Q0022627cellular_componentcytosolic small ribosomal subunit
Q0042254biological_processribosome biogenesis
Q1990904cellular_componentribonucleoprotein complex
R0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
R0003723molecular_functionRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0005737cellular_componentcytoplasm
R0005829cellular_componentcytosol
R0005840cellular_componentribosome
R0006412biological_processtranslation
R0006413biological_processtranslational initiation
R0022627cellular_componentcytosolic small ribosomal subunit
R0030686cellular_component90S preribosome
R1990904cellular_componentribonucleoprotein complex
S0000028biological_processribosomal small subunit assembly
S0002181biological_processcytoplasmic translation
S0003735molecular_functionstructural constituent of ribosome
S0005737cellular_componentcytoplasm
S0005829cellular_componentcytosol
S0005840cellular_componentribosome
S0006412biological_processtranslation
S0022627cellular_componentcytosolic small ribosomal subunit
S1990904cellular_componentribonucleoprotein complex
T0000054biological_processribosomal subunit export from nucleus
T0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
T0002181biological_processcytoplasmic translation
T0003676molecular_functionnucleic acid binding
T0003723molecular_functionRNA binding
T0003735molecular_functionstructural constituent of ribosome
T0005737cellular_componentcytoplasm
T0005739cellular_componentmitochondrion
T0005829cellular_componentcytosol
T0005840cellular_componentribosome
T0006412biological_processtranslation
T0015935cellular_componentsmall ribosomal subunit
T0019843molecular_functionrRNA binding
T0022627cellular_componentcytosolic small ribosomal subunit
T1990904cellular_componentribonucleoprotein complex
U0000028biological_processribosomal small subunit assembly
U0000054biological_processribosomal subunit export from nucleus
U0003723molecular_functionRNA binding
U0003735molecular_functionstructural constituent of ribosome
U0005737cellular_componentcytoplasm
U0005829cellular_componentcytosol
U0005840cellular_componentribosome
U0006412biological_processtranslation
U0022627cellular_componentcytosolic small ribosomal subunit
U0042254biological_processribosome biogenesis
U0042274biological_processribosomal small subunit biogenesis
U1990904cellular_componentribonucleoprotein complex
V0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V0002181biological_processcytoplasmic translation
V0003723molecular_functionRNA binding
V0003729molecular_functionmRNA binding
V0003735molecular_functionstructural constituent of ribosome
V0005737cellular_componentcytoplasm
V0005829cellular_componentcytosol
V0005840cellular_componentribosome
V0006412biological_processtranslation
V0015935cellular_componentsmall ribosomal subunit
V0022627cellular_componentcytosolic small ribosomal subunit
V1990904cellular_componentribonucleoprotein complex
W0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W0000461biological_processendonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W0003735molecular_functionstructural constituent of ribosome
W0005737cellular_componentcytoplasm
W0005829cellular_componentcytosol
W0005840cellular_componentribosome
W0006364biological_processrRNA processing
W0006412biological_processtranslation
W0022627cellular_componentcytosolic small ribosomal subunit
W1990904cellular_componentribonucleoprotein complex
X0002181biological_processcytoplasmic translation
X0003735molecular_functionstructural constituent of ribosome
X0005737cellular_componentcytoplasm
X0005829cellular_componentcytosol
X0005840cellular_componentribosome
X0006412biological_processtranslation
X0022627cellular_componentcytosolic small ribosomal subunit
X1990904cellular_componentribonucleoprotein complex
Y0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Y0003735molecular_functionstructural constituent of ribosome
Y0005737cellular_componentcytoplasm
Y0005829cellular_componentcytosol
Y0005840cellular_componentribosome
Y0006412biological_processtranslation
Y0006450biological_processregulation of translational fidelity
Y0015935cellular_componentsmall ribosomal subunit
Y0022627cellular_componentcytosolic small ribosomal subunit
Y1990145biological_processmaintenance of translational fidelity
Y1990904cellular_componentribonucleoprotein complex
Z0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z0002181biological_processcytoplasmic translation
Z0003735molecular_functionstructural constituent of ribosome
Z0005737cellular_componentcytoplasm
Z0005739cellular_componentmitochondrion
Z0005829cellular_componentcytosol
Z0005840cellular_componentribosome
Z0006412biological_processtranslation
Z0022627cellular_componentcytosolic small ribosomal subunit
Z1990904cellular_componentribonucleoprotein complex
a0002181biological_processcytoplasmic translation
a0003735molecular_functionstructural constituent of ribosome
a0005737cellular_componentcytoplasm
a0005829cellular_componentcytosol
a0005840cellular_componentribosome
a0022627cellular_componentcytosolic small ribosomal subunit
a1990904cellular_componentribonucleoprotein complex
b0000054biological_processribosomal subunit export from nucleus
b0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
b0002181biological_processcytoplasmic translation
b0003729molecular_functionmRNA binding
b0003735molecular_functionstructural constituent of ribosome
b0005515molecular_functionprotein binding
b0005737cellular_componentcytoplasm
b0005829cellular_componentcytosol
b0005840cellular_componentribosome
b0006412biological_processtranslation
b0008270molecular_functionzinc ion binding
b0022627cellular_componentcytosolic small ribosomal subunit
b0030686cellular_component90S preribosome
b0042255biological_processribosome assembly
b1990904cellular_componentribonucleoprotein complex
c0000028biological_processribosomal small subunit assembly
c0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
c0003723molecular_functionRNA binding
c0003735molecular_functionstructural constituent of ribosome
c0005737cellular_componentcytoplasm
c0005829cellular_componentcytosol
c0005840cellular_componentribosome
c0006412biological_processtranslation
c0008270molecular_functionzinc ion binding
c0022627cellular_componentcytosolic small ribosomal subunit
c0044391cellular_componentribosomal subunit
c0046872molecular_functionmetal ion binding
c1990904cellular_componentribonucleoprotein complex
d0000028biological_processribosomal small subunit assembly
d0000054biological_processribosomal subunit export from nucleus
d0002181biological_processcytoplasmic translation
d0003735molecular_functionstructural constituent of ribosome
d0005737cellular_componentcytoplasm
d0005829cellular_componentcytosol
d0005840cellular_componentribosome
d0006412biological_processtranslation
d0022627cellular_componentcytosolic small ribosomal subunit
d0030490biological_processmaturation of SSU-rRNA
d1900153biological_processpositive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
d1990904cellular_componentribonucleoprotein complex
e0002181biological_processcytoplasmic translation
e0003735molecular_functionstructural constituent of ribosome
e0005737cellular_componentcytoplasm
e0005829cellular_componentcytosol
e0005840cellular_componentribosome
e0006412biological_processtranslation
e0008270molecular_functionzinc ion binding
e0022627cellular_componentcytosolic small ribosomal subunit
e0046872molecular_functionmetal ion binding
e1990904cellular_componentribonucleoprotein complex
f0002181biological_processcytoplasmic translation
f0003735molecular_functionstructural constituent of ribosome
f0005737cellular_componentcytoplasm
f0005829cellular_componentcytosol
f0005840cellular_componentribosome
f0006412biological_processtranslation
f0010494cellular_componentcytoplasmic stress granule
f0022627cellular_componentcytosolic small ribosomal subunit
f1990904cellular_componentribonucleoprotein complex
g0000028biological_processribosomal small subunit assembly
g0002109biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)
g0002181biological_processcytoplasmic translation
g0003735molecular_functionstructural constituent of ribosome
g0005634cellular_componentnucleus
g0005737cellular_componentcytoplasm
g0005829cellular_componentcytosol
g0005840cellular_componentribosome
g0006412biological_processtranslation
g0008270molecular_functionzinc ion binding
g0016567biological_processprotein ubiquitination
g0019941biological_processmodification-dependent protein catabolic process
g0022627cellular_componentcytosolic small ribosomal subunit
g0031386molecular_functionprotein tag activity
g0031625molecular_functionubiquitin protein ligase binding
g0042254biological_processribosome biogenesis
g0044391cellular_componentribosomal subunit
g0046872molecular_functionmetal ion binding
g1990145biological_processmaintenance of translational fidelity
g1990904cellular_componentribonucleoprotein complex
h0001965molecular_functionG-protein alpha-subunit binding
h0002181biological_processcytoplasmic translation
h0005080molecular_functionprotein kinase C binding
h0005092molecular_functionGDP-dissociation inhibitor activity
h0005634cellular_componentnucleus
h0005737cellular_componentcytoplasm
h0005829cellular_componentcytosol
h0005840cellular_componentribosome
h0006521biological_processregulation of cellular amino acid metabolic process
h0007186biological_processG protein-coupled receptor signaling pathway
h0010629biological_processnegative regulation of gene expression
h0017148biological_processnegative regulation of translation
h0022627cellular_componentcytosolic small ribosomal subunit
h0043022molecular_functionribosome binding
h0045182molecular_functiontranslation regulator activity
h0061157biological_processmRNA destabilization
h0070651biological_processnonfunctional rRNA decay
h0072344biological_processrescue of stalled ribosome
h1902660biological_processnegative regulation of glucose mediated signaling pathway
h1990116biological_processribosome-associated ubiquitin-dependent protein catabolic process
h1990145biological_processmaintenance of translational fidelity
h1990904cellular_componentribonucleoprotein complex
h2001125biological_processnegative regulation of translational frameshifting
i0001677biological_processformation of translation initiation ternary complex
i0001731biological_processformation of translation preinitiation complex
i0001732biological_processformation of cytoplasmic translation initiation complex
i0002188biological_processtranslation reinitiation
i0003723molecular_functionRNA binding
i0003725molecular_functiondouble-stranded RNA binding
i0003743molecular_functiontranslation initiation factor activity
i0005515molecular_functionprotein binding
i0005737cellular_componentcytoplasm
i0006412biological_processtranslation
i0006413biological_processtranslational initiation
i0010494cellular_componentcytoplasmic stress granule
i0016282cellular_componenteukaryotic 43S preinitiation complex
i0019901molecular_functionprotein kinase binding
i0031369molecular_functiontranslation initiation factor binding
i0033290cellular_componenteukaryotic 48S preinitiation complex
i0043024molecular_functionribosomal small subunit binding
j0050825molecular_functionice binding
k0000054biological_processribosomal subunit export from nucleus
k0003743molecular_functiontranslation initiation factor activity
k0005506molecular_functioniron ion binding
k0005515molecular_functionprotein binding
k0005524molecular_functionATP binding
k0005634cellular_componentnucleus
k0005737cellular_componentcytoplasm
k0005852cellular_componenteukaryotic translation initiation factor 3 complex
k0006364biological_processrRNA processing
k0006412biological_processtranslation
k0006413biological_processtranslational initiation
k0006415biological_processtranslational termination
k0016887molecular_functionATP hydrolysis activity
k0032790biological_processribosome disassembly
k0042254biological_processribosome biogenesis
k0042273biological_processribosomal large subunit biogenesis
k0043024molecular_functionribosomal small subunit binding
k0045727biological_processpositive regulation of translation
l0001732biological_processformation of cytoplasmic translation initiation complex
l0002183biological_processcytoplasmic translational initiation
l0002188biological_processtranslation reinitiation
l0003723molecular_functionRNA binding
l0003743molecular_functiontranslation initiation factor activity
l0005515molecular_functionprotein binding
l0005737cellular_componentcytoplasm
l0005852cellular_componenteukaryotic translation initiation factor 3 complex
l0006412biological_processtranslation
l0006413biological_processtranslational initiation
l0010494cellular_componentcytoplasmic stress granule
l0016282cellular_componenteukaryotic 43S preinitiation complex
l0033290cellular_componenteukaryotic 48S preinitiation complex
l0043614cellular_componentmulti-eIF complex
l0071541cellular_componenteukaryotic translation initiation factor 3 complex, eIF3m
m0001731biological_processformation of translation preinitiation complex
m0003723molecular_functionRNA binding
m0003743molecular_functiontranslation initiation factor activity
m0005515molecular_functionprotein binding
m0006412biological_processtranslation
m0006413biological_processtranslational initiation
m0006417biological_processregulation of translation
m0006450biological_processregulation of translational fidelity
m0016282cellular_componenteukaryotic 43S preinitiation complex
m0031369molecular_functiontranslation initiation factor binding
m0043024molecular_functionribosomal small subunit binding
m0043614cellular_componentmulti-eIF complex
m1990145biological_processmaintenance of translational fidelity
o0000131cellular_componentincipient cellular bud site
o0001732biological_processformation of cytoplasmic translation initiation complex
o0002183biological_processcytoplasmic translational initiation
o0002188biological_processtranslation reinitiation
o0003723molecular_functionRNA binding
o0003729molecular_functionmRNA binding
o0003743molecular_functiontranslation initiation factor activity
o0005515molecular_functionprotein binding
o0005737cellular_componentcytoplasm
o0005852cellular_componenteukaryotic translation initiation factor 3 complex
o0006412biological_processtranslation
o0006413biological_processtranslational initiation
o0010494cellular_componentcytoplasmic stress granule
o0016282cellular_componenteukaryotic 43S preinitiation complex
o0033290cellular_componenteukaryotic 48S preinitiation complex
o0043614cellular_componentmulti-eIF complex
o0071540cellular_componenteukaryotic translation initiation factor 3 complex, eIF3e
o0071541cellular_componenteukaryotic translation initiation factor 3 complex, eIF3m
p0001732biological_processformation of cytoplasmic translation initiation complex
p0002183biological_processcytoplasmic translational initiation
p0003676molecular_functionnucleic acid binding
p0003723molecular_functionRNA binding
p0003743molecular_functiontranslation initiation factor activity
p0005515molecular_functionprotein binding
p0005737cellular_componentcytoplasm
p0005852cellular_componenteukaryotic translation initiation factor 3 complex
p0006412biological_processtranslation
p0006413biological_processtranslational initiation
p0010494cellular_componentcytoplasmic stress granule
p0016282cellular_componenteukaryotic 43S preinitiation complex
p0031369molecular_functiontranslation initiation factor binding
p0033290cellular_componenteukaryotic 48S preinitiation complex
p0042802molecular_functionidentical protein binding
p0043614cellular_componentmulti-eIF complex
q0001732biological_processformation of cytoplasmic translation initiation complex
q0002183biological_processcytoplasmic translational initiation
q0003723molecular_functionRNA binding
q0003729molecular_functionmRNA binding
q0003743molecular_functiontranslation initiation factor activity
q0005515molecular_functionprotein binding
q0005737cellular_componentcytoplasm
q0005852cellular_componenteukaryotic translation initiation factor 3 complex
q0006412biological_processtranslation
q0006413biological_processtranslational initiation
q0010494cellular_componentcytoplasmic stress granule
q0016282cellular_componenteukaryotic 43S preinitiation complex
q0031369molecular_functiontranslation initiation factor binding
q0033290cellular_componenteukaryotic 48S preinitiation complex
q0043614cellular_componentmulti-eIF complex
r0001732biological_processformation of cytoplasmic translation initiation complex
r0002183biological_processcytoplasmic translational initiation
r0002188biological_processtranslation reinitiation
r0003676molecular_functionnucleic acid binding
r0003723molecular_functionRNA binding
r0003743molecular_functiontranslation initiation factor activity
r0005515molecular_functionprotein binding
r0005737cellular_componentcytoplasm
r0005852cellular_componenteukaryotic translation initiation factor 3 complex
r0006412biological_processtranslation
r0006413biological_processtranslational initiation
r0006415biological_processtranslational termination
r0008270molecular_functionzinc ion binding
r0010494cellular_componentcytoplasmic stress granule
r0016282cellular_componenteukaryotic 43S preinitiation complex
r0033290cellular_componenteukaryotic 48S preinitiation complex
r0043614cellular_componentmulti-eIF complex
s0000184biological_processnuclear-transcribed mRNA catabolic process, nonsense-mediated decay
s0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
s0001732biological_processformation of cytoplasmic translation initiation complex
s0002181biological_processcytoplasmic translation
s0002183biological_processcytoplasmic translational initiation
s0003743molecular_functiontranslation initiation factor activity
s0005515molecular_functionprotein binding
s0005737cellular_componentcytoplasm
s0005852cellular_componenteukaryotic translation initiation factor 3 complex
s0006412biological_processtranslation
s0006413biological_processtranslational initiation
s0010494cellular_componentcytoplasmic stress granule
s0016282cellular_componenteukaryotic 43S preinitiation complex
s0033290cellular_componenteukaryotic 48S preinitiation complex
t0000184biological_processnuclear-transcribed mRNA catabolic process, nonsense-mediated decay
t0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
t0001732biological_processformation of cytoplasmic translation initiation complex
t0002181biological_processcytoplasmic translation
t0002183biological_processcytoplasmic translational initiation
t0003743molecular_functiontranslation initiation factor activity
t0005515molecular_functionprotein binding
t0005737cellular_componentcytoplasm
t0005852cellular_componenteukaryotic translation initiation factor 3 complex
t0006412biological_processtranslation
t0006413biological_processtranslational initiation
t0010494cellular_componentcytoplasmic stress granule
t0016282cellular_componenteukaryotic 43S preinitiation complex
t0033290cellular_componenteukaryotic 48S preinitiation complex
Functional Information from PROSITE/UniProt
site_idPS00052
Number of Residues27
DetailsRIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIIkhT
ChainResidueDetails
GGLU91-THR117

site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR
ChainResidueDetails
XGLY100-ARG117

site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD
ChainResidueDetails
PLEU102-ASP124

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR
ChainResidueDetails
YLYS62-ARG69

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS
ChainResidueDetails
MGLY120-SER132

site_idPS00198
Number of Residues12
Details4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiGCGiCVkKCP
ChainResidueDetails
kCYS55-PRO66

site_idPS00211
Number of Residues15
DetailsABC_TRANSPORTER_1 ABC transporters family signature. LSGGELQRVAIVLAL
ChainResidueDetails
kLEU468-LEU482

site_idPS00299
Number of Residues26
DetailsUBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD
ChainResidueDetails
gLYS27-ASP52

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGKafnqveIrpemLGhyLGEFsiT
ChainResidueDetails
QASN98-THR122

site_idPS00360
Number of Residues19
DetailsRIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL
ChainResidueDetails
RGLY71-LEU89

site_idPS00361
Number of Residues16
DetailsRIBOSOMAL_S10 Ribosomal protein S10 signature. AeqhNLvkkGPVrLPT
ChainResidueDetails
VALA45-THR60

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY
ChainResidueDetails
OVAL98-TYR128

site_idPS00527
Number of Residues23
DetailsRIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsshtglirkyg.LNICRqCFR
ChainResidueDetails
eARG22-ARG44

site_idPS00528
Number of Residues15
DetailsRIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWlLdK
ChainResidueDetails
FHIS8-LYS22

site_idPS00529
Number of Residues23
DetailsRIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKSvGFGlVYNSvaeakkfE
ChainResidueDetails
ZPHE64-GLU86

site_idPS00548
Number of Residues37
DetailsRIBOSOMAL_S3 Ribosomal protein S3 signature. AKamkfadGfLihSgqpVndfIDtatrhvlMrqGvlG
ChainResidueDetails
EALA147-GLY183

site_idPS00578
Number of Residues12
DetailsRIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM
ChainResidueDetails
HILE52-MET63

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI
ChainResidueDetails
DGLY93-ILE125

site_idPS00628
Number of Residues20
DetailsRIBOSOMAL_S19E Ribosomal protein S19e signature. PykhidaSgsInRkVLQaLE
ChainResidueDetails
UPRO90-GLU109

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI
ChainResidueDetails
KLEU105-ILE129

site_idPS00646
Number of Residues14
DetailsRIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHfwGlrVRGQ
ChainResidueDetails
TARG123-GLN136

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSAswDkTLRLWDV
ChainResidueDetails
hALA80-VAL94
hILE169-LEU183
hILE211-LEU225
lCYS67-VAL81

site_idPS00712
Number of Residues16
DetailsRIBOSOMAL_S17E Ribosomal protein S17e signature. IqSKrLRNkIAGYtTH
ChainResidueDetails
SILE41-HIS56

site_idPS00733
Number of Residues8
DetailsRIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH
ChainResidueDetails
bTYR73-HIS80

site_idPS00948
Number of Residues14
DetailsRIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH
ChainResidueDetails
ILYS76-HIS89

site_idPS00961
Number of Residues9
DetailsRIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL
ChainResidueDetails
dGLU58-LEU66

site_idPS00962
Number of Residues12
DetailsRIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. AqLLLAANTHLG
ChainResidueDetails
BALA14-GLY25

site_idPS00963
Number of Residues25
DetailsRIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlVIVtDprsDaqaIkEasyvNIP
ChainResidueDetails
BPRO118-PRO142

site_idPS00996
Number of Residues9
DetailsRIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA
ChainResidueDetails
WLEU11-ALA19

site_idPS01168
Number of Residues33
DetailsRIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStiLctPtG
ChainResidueDetails
cLYS36-GLY68

site_idPS01189
Number of Residues19
DetailsRIBOSOMAL_S12E Ribosomal protein S12e signature. ALKvvLrtAlvhDGLarGL
ChainResidueDetails
NALA27-LEU45

site_idPS01191
Number of Residues13
DetailsRIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL
ChainResidueDetails
CLEU61-LEU73

site_idPS01193
Number of Residues20
DetailsRIBOSOMAL_S8E Ribosomal protein S8e signature. RsaTGAkraqf.RkKrKfELG
ChainResidueDetails
JARG11-GLY30

site_idPS01262
Number of Residues23
DetailsIF1A Eukaryotic initiation factor 1A signature. MlGnGRveasCfDGnkRmaHIrG
ChainResidueDetails
iMET41-GLY63

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434
ChainResidueDetails
kGLY110
kGLY385
qSER103
NLYS114

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
kSER349
MLYS141
MLYS148
sTHR75
QLYS35
QLYS64
MLYS57
MLYS79
MLYS96
MLYS105
MLYS133

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
tSER92
gLYS113
sSER92
VLYS32
VLYS101
TLYS96
gLYS33
gLYS48
gLYS63
gLYS107

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Omega-N-methylarginine => ECO:0000269|PubMed:33856219
ChainResidueDetails
tARG220
sARG220
hLYS53
hLYS107
hLYS137
hLYS161
FLYS179
FLYS211
FLYS233

site_idSWS_FT_FI5
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
RLYS30
RLYS47
RLYS59

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
JSER158

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
ETHR231

site_idSWS_FT_FI8
Number of Residues5
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
ELYS106
ELYS132
ELYS141
ELYS151
ELYS200

site_idSWS_FT_FI9
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:28757607, ECO:0000269|PubMed:30718516, ECO:0000269|PubMed:30893611, ECO:0000269|PubMed:31819057, ECO:0007744|PubMed:22106047
ChainResidueDetails
ELYS212

226707

PDB entries from 2024-10-30

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