Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6Z9T

Transcription termination intermediate complex 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001000	molecular_function	bacterial-type RNA polymerase core enzyme binding
A	0003676	molecular_function	nucleic acid binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006353	biological_process	DNA-templated transcription termination
A	0008023	cellular_component	transcription elongation factor complex
A	0019904	molecular_function	protein domain specific binding
A	0031554	biological_process	regulation of termination of DNA-templated transcription
A	0031564	biological_process	transcription antitermination
A	0032784	biological_process	regulation of DNA-templated transcription elongation
A	0042254	biological_process	ribosome biogenesis
A	0051259	biological_process	protein complex oligomerization
U	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
U	0000428	cellular_component	DNA-directed RNA polymerase complex
U	0003677	molecular_function	DNA binding
U	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006351	biological_process	DNA-templated transcription
U	0006352	biological_process	DNA-templated transcription initiation
U	0006879	biological_process	intracellular iron ion homeostasis
U	0008023	cellular_component	transcription elongation factor complex
U	0009408	biological_process	response to heat
U	0016020	cellular_component	membrane
U	0016779	molecular_function	nucleotidyltransferase activity
U	0031564	biological_process	transcription antitermination
U	0032784	biological_process	regulation of DNA-templated transcription elongation
U	0034062	molecular_function	5'-3' RNA polymerase activity
U	0036460	biological_process	cellular response to cell envelope stress
U	0042128	biological_process	nitrate assimilation
U	0044780	biological_process	bacterial-type flagellum assembly
U	0046983	molecular_function	protein dimerization activity
U	0048870	biological_process	cell motility
U	0071973	biological_process	bacterial-type flagellum-dependent cell motility
U	0090605	biological_process	submerged biofilm formation
U	2000142	biological_process	regulation of DNA-templated transcription initiation
V	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
V	0000428	cellular_component	DNA-directed RNA polymerase complex
V	0003677	molecular_function	DNA binding
V	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
V	0005515	molecular_function	protein binding
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006351	biological_process	DNA-templated transcription
V	0006352	biological_process	DNA-templated transcription initiation
V	0006879	biological_process	intracellular iron ion homeostasis
V	0008023	cellular_component	transcription elongation factor complex
V	0009408	biological_process	response to heat
V	0016020	cellular_component	membrane
V	0016779	molecular_function	nucleotidyltransferase activity
V	0031564	biological_process	transcription antitermination
V	0032784	biological_process	regulation of DNA-templated transcription elongation
V	0034062	molecular_function	5'-3' RNA polymerase activity
V	0036460	biological_process	cellular response to cell envelope stress
V	0042128	biological_process	nitrate assimilation
V	0044780	biological_process	bacterial-type flagellum assembly
V	0046983	molecular_function	protein dimerization activity
V	0048870	biological_process	cell motility
V	0071973	biological_process	bacterial-type flagellum-dependent cell motility
V	0090605	biological_process	submerged biofilm formation
V	2000142	biological_process	regulation of DNA-templated transcription initiation
W	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
W	0000428	cellular_component	DNA-directed RNA polymerase complex
W	0001000	molecular_function	bacterial-type RNA polymerase core enzyme binding
W	0003677	molecular_function	DNA binding
W	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
W	0005829	cellular_component	cytosol
W	0006351	biological_process	DNA-templated transcription
W	0006352	biological_process	DNA-templated transcription initiation
W	0006879	biological_process	intracellular iron ion homeostasis
W	0008023	cellular_component	transcription elongation factor complex
W	0009408	biological_process	response to heat
W	0016779	molecular_function	nucleotidyltransferase activity
W	0030880	cellular_component	RNA polymerase complex
W	0031564	biological_process	transcription antitermination
W	0032784	biological_process	regulation of DNA-templated transcription elongation
W	0034062	molecular_function	5'-3' RNA polymerase activity
W	0036460	biological_process	cellular response to cell envelope stress
W	0042128	biological_process	nitrate assimilation
W	0044780	biological_process	bacterial-type flagellum assembly
W	0048870	biological_process	cell motility
W	0065003	biological_process	protein-containing complex assembly
W	0071973	biological_process	bacterial-type flagellum-dependent cell motility
W	0090605	biological_process	submerged biofilm formation
W	2000142	biological_process	regulation of DNA-templated transcription initiation
X	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
X	0000428	cellular_component	DNA-directed RNA polymerase complex
X	0003677	molecular_function	DNA binding
X	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006351	biological_process	DNA-templated transcription
X	0006352	biological_process	DNA-templated transcription initiation
X	0006879	biological_process	intracellular iron ion homeostasis
X	0008023	cellular_component	transcription elongation factor complex
X	0009408	biological_process	response to heat
X	0016020	cellular_component	membrane
X	0016779	molecular_function	nucleotidyltransferase activity
X	0031564	biological_process	transcription antitermination
X	0032549	molecular_function	ribonucleoside binding
X	0032784	biological_process	regulation of DNA-templated transcription elongation
X	0034062	molecular_function	5'-3' RNA polymerase activity
X	0036460	biological_process	cellular response to cell envelope stress
X	0042128	biological_process	nitrate assimilation
X	0044780	biological_process	bacterial-type flagellum assembly
X	0046677	biological_process	response to antibiotic
X	0048870	biological_process	cell motility
X	0071973	biological_process	bacterial-type flagellum-dependent cell motility
X	0090605	biological_process	submerged biofilm formation
X	2000142	biological_process	regulation of DNA-templated transcription initiation
Y	0000287	molecular_function	magnesium ion binding
Y	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
Y	0000428	cellular_component	DNA-directed RNA polymerase complex
Y	0003677	molecular_function	DNA binding
Y	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
Y	0005515	molecular_function	protein binding
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0006351	biological_process	DNA-templated transcription
Y	0006352	biological_process	DNA-templated transcription initiation
Y	0006879	biological_process	intracellular iron ion homeostasis
Y	0008023	cellular_component	transcription elongation factor complex
Y	0008270	molecular_function	zinc ion binding
Y	0009408	biological_process	response to heat
Y	0016020	cellular_component	membrane
Y	0016779	molecular_function	nucleotidyltransferase activity
Y	0031564	biological_process	transcription antitermination
Y	0032784	biological_process	regulation of DNA-templated transcription elongation
Y	0034062	molecular_function	5'-3' RNA polymerase activity
Y	0036460	biological_process	cellular response to cell envelope stress
Y	0042128	biological_process	nitrate assimilation
Y	0044780	biological_process	bacterial-type flagellum assembly
Y	0046677	biological_process	response to antibiotic
Y	0046872	molecular_function	metal ion binding
Y	0048870	biological_process	cell motility
Y	0071973	biological_process	bacterial-type flagellum-dependent cell motility
Y	0090605	biological_process	submerged biofilm formation
Y	2000142	biological_process	regulation of DNA-templated transcription initiation
a	0003676	molecular_function	nucleic acid binding
a	0003723	molecular_function	RNA binding
a	0004386	molecular_function	helicase activity
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005829	cellular_component	cytosol
a	0006353	biological_process	DNA-templated transcription termination
a	0008186	molecular_function	ATP-dependent activity, acting on RNA
a	0016020	cellular_component	membrane
a	0016787	molecular_function	hydrolase activity
a	0016887	molecular_function	ATP hydrolysis activity
a	0042802	molecular_function	identical protein binding
b	0003676	molecular_function	nucleic acid binding
b	0003723	molecular_function	RNA binding
b	0004386	molecular_function	helicase activity
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005829	cellular_component	cytosol
b	0006353	biological_process	DNA-templated transcription termination
b	0008186	molecular_function	ATP-dependent activity, acting on RNA
b	0016020	cellular_component	membrane
b	0016787	molecular_function	hydrolase activity
b	0016887	molecular_function	ATP hydrolysis activity
b	0042802	molecular_function	identical protein binding
c	0003676	molecular_function	nucleic acid binding
c	0003723	molecular_function	RNA binding
c	0004386	molecular_function	helicase activity
c	0005515	molecular_function	protein binding
c	0005524	molecular_function	ATP binding
c	0005829	cellular_component	cytosol
c	0006353	biological_process	DNA-templated transcription termination
c	0008186	molecular_function	ATP-dependent activity, acting on RNA
c	0016020	cellular_component	membrane
c	0016787	molecular_function	hydrolase activity
c	0016887	molecular_function	ATP hydrolysis activity
c	0042802	molecular_function	identical protein binding
d	0003676	molecular_function	nucleic acid binding
d	0003723	molecular_function	RNA binding
d	0004386	molecular_function	helicase activity
d	0005515	molecular_function	protein binding
d	0005524	molecular_function	ATP binding
d	0005829	cellular_component	cytosol
d	0006353	biological_process	DNA-templated transcription termination
d	0008186	molecular_function	ATP-dependent activity, acting on RNA
d	0016020	cellular_component	membrane
d	0016787	molecular_function	hydrolase activity
d	0016887	molecular_function	ATP hydrolysis activity
d	0042802	molecular_function	identical protein binding
e	0003676	molecular_function	nucleic acid binding
e	0003723	molecular_function	RNA binding
e	0004386	molecular_function	helicase activity
e	0005515	molecular_function	protein binding
e	0005524	molecular_function	ATP binding
e	0005829	cellular_component	cytosol
e	0006353	biological_process	DNA-templated transcription termination
e	0008186	molecular_function	ATP-dependent activity, acting on RNA
e	0016020	cellular_component	membrane
e	0016787	molecular_function	hydrolase activity
e	0016887	molecular_function	ATP hydrolysis activity
e	0042802	molecular_function	identical protein binding
f	0003676	molecular_function	nucleic acid binding
f	0003723	molecular_function	RNA binding
f	0004386	molecular_function	helicase activity
f	0005515	molecular_function	protein binding
f	0005524	molecular_function	ATP binding
f	0005829	cellular_component	cytosol
f	0006353	biological_process	DNA-templated transcription termination
f	0008186	molecular_function	ATP-dependent activity, acting on RNA
f	0016020	cellular_component	membrane
f	0016787	molecular_function	hydrolase activity
f	0016887	molecular_function	ATP hydrolysis activity
f	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue ADP a 1000

Chain	Residue
a	ALA182
f	ARG366
f	LYS367
f	GLU369
a	GLY183
a	LYS184
a	THR185
a	MET186
a	PHE355
a	MG1001
a	BEF1002
a	HOH1102

site_id	AC2
Number of Residues	6
Details	binding site for residue MG a 1001

Chain	Residue
a	THR185
a	ADP1000
a	BEF1002
a	HOH1101
a	HOH1102
a	HOH1103

site_id	AC3
Number of Residues	8
Details	binding site for residue BEF a 1002

Chain	Residue
a	LYS181
a	LYS184
a	ADP1000
a	MG1001
a	HOH1101
a	HOH1102
a	HOH1103
f	ARG366

site_id	AC4
Number of Residues	13
Details	binding site for residue ADP b 1000

Chain	Residue
a	ARG366
a	GLU369
b	THR158
b	LYS181
b	ALA182
b	GLY183
b	LYS184
b	THR185
b	MET186
b	PHE355
b	MG1001
b	BEF1002
b	HOH1101

site_id	AC5
Number of Residues	6
Details	binding site for residue MG b 1001

Chain	Residue
b	THR185
b	ADP1000
b	BEF1002
b	HOH1101
b	HOH1102
b	HOH1103

site_id	AC6
Number of Residues	8
Details	binding site for residue BEF b 1002

Chain	Residue
a	ARG366
b	PRO180
b	LYS181
b	ADP1000
b	MG1001
b	HOH1101
b	HOH1102
b	HOH1103

site_id	AC7
Number of Residues	12
Details	binding site for residue ADP c 1000

Chain	Residue
b	ARG366
b	LYS367
b	GLU369
c	LYS181
c	ALA182
c	GLY183
c	LYS184
c	THR185
c	MET186
c	MG1001
c	BEF1002
c	HOH1103

site_id	AC8
Number of Residues	7
Details	binding site for residue MG c 1001

Chain	Residue
c	LYS184
c	THR185
c	ADP1000
c	BEF1002
c	HOH1101
c	HOH1102
c	HOH1103

site_id	AC9
Number of Residues	8
Details	binding site for residue BEF c 1002

Chain	Residue
b	ARG366
c	PRO180
c	LYS181
c	ADP1000
c	MG1001
c	HOH1101
c	HOH1102
c	HOH1103

site_id	AD1
Number of Residues	12
Details	binding site for residue ADP d 1000

Chain	Residue
c	ARG366
c	GLU369
d	LYS181
d	ALA182
d	GLY183
d	LYS184
d	THR185
d	MET186
d	PHE355
d	MG1001
d	BEF1002
d	HOH1101

site_id	AD2
Number of Residues	6
Details	binding site for residue MG d 1001

Chain	Residue
d	THR185
d	ADP1000
d	BEF1002
d	HOH1101
d	HOH1102
d	HOH1103

site_id	AD3
Number of Residues	9
Details	binding site for residue BEF d 1002

Chain	Residue
d	PRO180
d	LYS181
d	LYS184
d	ADP1000
d	MG1001
d	HOH1101
d	HOH1102
d	HOH1103
c	ARG366

site_id	AD4
Number of Residues	12
Details	binding site for residue ADP e 1000

Chain	Residue
d	ARG366
d	GLU369
e	LYS181
e	ALA182
e	GLY183
e	LYS184
e	THR185
e	MET186
e	PHE355
e	MG1001
e	BEF1002
e	HOH1102

site_id	AD5
Number of Residues	6
Details	binding site for residue MG e 1001

Chain	Residue
e	THR185
e	ADP1000
e	BEF1002
e	HOH1101
e	HOH1102
e	HOH1103

site_id	AD6
Number of Residues	10
Details	binding site for residue BEF e 1002

Chain	Residue
d	ARG366
e	PRO180
e	LYS181
e	ALA182
e	LYS184
e	ADP1000
e	MG1001
e	HOH1101
e	HOH1102
e	HOH1103

site_id	AD7
Number of Residues	3
Details	binding site for residue MG Y 1501

Chain	Residue
Y	ASP460
Y	ASP462
Y	ASP464

site_id	AD8
Number of Residues	4
Details	binding site for residue ZN Y 1502

Chain	Residue
Y	CYS70
Y	CYS72
Y	CYS85
Y	CYS88

site_id	AD9
Number of Residues	4
Details	binding site for residue ZN Y 1503

Chain	Residue
Y	CYS814
Y	CYS888
Y	CYS895
Y	CYS898

site_id	AE1
Number of Residues	4
Details	binding site for residue DT Y 1504

Chain	Residue
L	DT101
Y	THR48
Y	LYS50
Y	DA1505

site_id	AE2
Number of Residues	4
Details	binding site for residue DA Y 1505

Chain	Residue
Y	LYS50
Y	GLU86
Y	LYS87
Y	DT1504

site_id	AE3
Number of Residues	6
Details	binding site for residue DT L 101

Chain	Residue
L	DG22
Y	ASN45
Y	DT1504
a	GLY107
a	GLU108
a	ARG109

Functional Information from PROSITE/UniProt

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV

Chain	Residue	Details
X	GLY1063-VAL1075

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
f	GLY169
Y	CYS895
Y	CYS898
a	GLY169
b	GLY169
c	GLY169
d	GLY169
e	GLY169
Y	ASP464
Y	CYS814
Y	CYS888

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
f	LYS181
d	ARG212
e	LYS181
e	ARG212
f	ARG212
a	LYS181
a	ARG212
b	LYS181
b	ARG212
c	LYS181
c	ARG212
d	LYS181

site_id	SWS_FT_FI3
Number of Residues	6
Details	SITE: RNA-binding 2

Chain	Residue	Details
f	LYS326
a	LYS326
b	LYS326
c	LYS326
d	LYS326
e	LYS326

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)