6Z70
Structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0035350 | biological_process | FAD transmembrane transport |
| A | 0042908 | biological_process | xenobiotic transport |
| A | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| A | 0044610 | molecular_function | FMN transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 1901264 | biological_process | carbohydrate derivative transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0015297 | molecular_function | antiporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0035350 | biological_process | FAD transmembrane transport |
| B | 0042908 | biological_process | xenobiotic transport |
| B | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| B | 0044610 | molecular_function | FMN transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
| B | 1901264 | biological_process | carbohydrate derivative transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue OLC A 501 |
| Chain | Residue |
| A | LEU68 |
| B | ILE393 |
| B | SER394 |
| B | TRP397 |
| B | OLC502 |
| A | LEU103 |
| A | PRO107 |
| A | TYR111 |
| A | PHE115 |
| A | PHE118 |
| B | LEU255 |
| B | ASN258 |
| B | VAL259 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue OLC A 502 |
| Chain | Residue |
| A | LYS384 |
| A | SER394 |
| A | VAL439 |
| A | LYS442 |
| B | LEU71 |
| B | LEU103 |
| B | PRO233 |
| B | LYS234 |
| B | OLC501 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue OLC A 503 |
| Chain | Residue |
| A | TRP63 |
| A | TYR66 |
| A | SER67 |
| A | MET69 |
| A | TYR73 |
| A | GLY147 |
| A | THR150 |
| A | ASN151 |
| A | GLU207 |
| A | PHE290 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue OLC A 504 |
| Chain | Residue |
| A | ASN37 |
| A | MET41 |
| A | LEU59 |
| A | SER60 |
| A | TRP63 |
| A | ARG250 |
| A | THR253 |
| A | THR254 |
| A | PHE257 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue OLC B 501 |
| Chain | Residue |
| A | LEU123 |
| A | ASN258 |
| A | ILE393 |
| A | SER394 |
| A | TRP397 |
| A | OLC502 |
| B | LEU68 |
| B | LEU103 |
| B | ILE104 |
| B | LEU106 |
| B | PRO107 |
| B | TYR111 |
| B | PHE115 |
| B | PHE118 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue OLC B 502 |
| Chain | Residue |
| A | LEU103 |
| A | PRO233 |
| A | LYS234 |
| A | PHE237 |
| A | OLC501 |
| B | LYS384 |
| B | LEU389 |
| B | VAL439 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue OLC B 503 |
| Chain | Residue |
| B | TRP63 |
| B | TYR66 |
| B | SER67 |
| B | MET69 |
| B | ALA70 |
| B | TYR73 |
| B | GLY147 |
| B | THR150 |
| B | ASN151 |
| B | TYR154 |
| B | MET173 |
| B | GLU207 |
| B | ARG250 |
| B | PHE290 |
