6Z6G
Cryo-EM structure of La Crosse virus polymerase at pre-initiation stage
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001172 | biological_process | RNA-templated transcription |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019079 | biological_process | viral genome replication |
| A | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| A | 0044165 | cellular_component | host cell endoplasmic reticulum |
| A | 0044172 | cellular_component | host cell endoplasmic reticulum-Golgi intermediate compartment |
| A | 0044177 | cellular_component | host cell Golgi apparatus |
| A | 0044423 | cellular_component | virion component |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. MGSiNLTITGYNRSItI |
| Chain | Residue | Details |
| A | MET1858-ILE1874 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 188 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 184 |
| Details | Region: {"description":"Endonuclease","evidences":[{"source":"PubMed","id":"32681014","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20862319","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26004069","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32681014","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6Z6B","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
