6Z4N
CRYSTAL STRUCTURE OF OASS COMPLEXED WITH UPAR INHIBITOR
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0004124 | molecular_function | cysteine synthase activity |
| AAA | 0005737 | cellular_component | cytoplasm |
| AAA | 0006535 | biological_process | cysteine biosynthetic process from serine |
| AAA | 0016740 | molecular_function | transferase activity |
| AAA | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| AAA | 0019344 | biological_process | cysteine biosynthetic process |
| AAA | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| BBB | 0004124 | molecular_function | cysteine synthase activity |
| BBB | 0005737 | cellular_component | cytoplasm |
| BBB | 0006535 | biological_process | cysteine biosynthetic process from serine |
| BBB | 0016740 | molecular_function | transferase activity |
| BBB | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| BBB | 0019344 | biological_process | cysteine biosynthetic process |
| BBB | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KvEsrn.PSfSVKcRiGanM |
| Chain | Residue | Details |
| AAA | LYS30-MET48 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:11023792 |
| Chain | Residue | Details |
| BBB | ASN7 | |
| AAA | ASN7 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: in other chain => ECO:0000305|PubMed:11023792 |
| Chain | Residue | Details |
| BBB | ARG34 | |
| BBB | LEU268 | |
| AAA | LEU268 | |
| AAA | ARG34 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10452898, ECO:0000269|PubMed:11023792, ECO:0000269|PubMed:9761678 |
| Chain | Residue | Details |
| BBB | ASN71 | |
| BBB | SER272 | |
| AAA | ASN71 | |
| AAA | SER272 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| BBB | GLY176 | |
| AAA | GLY176 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine |
| Chain | Residue | Details |
| BBB | LYS41 | |
| AAA | LYS41 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 865 |
| Chain | Residue | Details |
| AAA | LYS41 | covalent catalysis, proton shuttle (general acid/base) |
| AAA | SER272 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 865 |
| Chain | Residue | Details |
| BBB | LYS41 | covalent catalysis, proton shuttle (general acid/base) |
| BBB | SER272 | electrostatic stabiliser |
