Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0003677 | molecular_function | DNA binding |
B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006259 | biological_process | DNA metabolic process |
B | 0006265 | biological_process | DNA topological change |
D | 0003677 | molecular_function | DNA binding |
D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
D | 0005524 | molecular_function | ATP binding |
D | 0006259 | biological_process | DNA metabolic process |
D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue EPE B 1701 |
Chain | Residue |
B | ASN1182 |
B | GLN1267 |
B | VAL1268 |
B | ASN1269 |
B | ARG1272 |
B | PRO1326 |
E | DC3 |
E | DC4 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue MN B 1702 |
Chain | Residue |
B | ASP510 |
B | HOH1815 |
B | HOH1834 |
B | HOH1861 |
B | HOH1869 |
B | ASP508 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue DMS D 1601 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue DMS D 1602 |
Chain | Residue |
D | ARG630 |
D | MET1179 |
D | PRO1343 |
D | HOH1791 |
site_id | AC5 |
Number of Residues | 9 |
Details | binding site for residue EPE D 1603 |
Chain | Residue |
D | ASN1182 |
D | GLN1267 |
D | VAL1268 |
D | ASN1269 |
D | ARG1272 |
D | PRO1326 |
D | HOH1792 |
F | DC3 |
F | DC4 |
site_id | AC6 |
Number of Residues | 1 |
Details | binding site for residue CL D 1604 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue MN D 1605 |
Chain | Residue |
D | GLU435 |
D | ASP508 |
D | HOH1705 |
D | HOH1777 |
F | DG8 |
H | DG2009 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue MN D 1606 |
Chain | Residue |
D | HIS1390 |
D | HOH1836 |
D | HOH1840 |
D | HOH1853 |
E | DA1 |
E | HOH1702 |
E | HOH1707 |
site_id | AC9 |
Number of Residues | 1 |
Details | binding site for residue DMS E 1601 |
site_id | AD1 |
Number of Residues | 8 |
Details | binding site for residue Q52 G 2101 |
Chain | Residue |
B | ASP1083 |
B | MET1121 |
D | ALA1068 |
D | ASP1083 |
G | DT2010 |
G | DA2011 |
H | DT2010 |
H | DA2011 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue MN G 2102 |
Chain | Residue |
E | HOH1704 |
E | HOH1708 |
G | DG2009 |
G | HOH2201 |
G | HOH2204 |
G | HOH2208 |
Functional Information from PROSITE/UniProt
site_id | PS00177 |
Number of Residues | 9 |
Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
Chain | Residue | Details |
B | LEU433-GLY441 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
B | GLU435 | |
B | ASP508 | |
B | ASP510 | |
D | GLU435 | |
D | ASP508 | |
D | ASP510 | |
Chain | Residue | Details |
B | LYS460 | |
B | ASN463 | |
D | LYS460 | |
D | ASN463 | |
Chain | Residue | Details |
B | PHE1123 | |
D | PHE1123 | |