Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | HIS160 |
| A | VAL161 |
| A | HOH606 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | GLU213 |
| A | MET215 |
| A | ASP277 |
| A | HOH761 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | HOH826 |
| A | THR201 |
| A | EDO504 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | THR201 |
| A | ILE203 |
| A | ILE305 |
| A | ASP306 |
| A | EDO503 |
| A | HOH605 |
| A | HOH714 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | PRO231 |
| A | GLU232 |
| A | MET363 |
| A | GLY364 |
| A | HOH796 |
| A | HOH806 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLU251 |
| A | LYS252 |
| A | HIS253 |
| A | GLY254 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | ARG156 |
| A | TYR247 |
| A | ASN388 |
| A | LEU391 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | TYR338 |
| A | CYS341 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | GLN353 |
| A | GLU354 |
| A | GLU355 |
| A | LYS379 |
| A | HOH803 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 510 |
| Chain | Residue |
| A | ALA131 |
| A | GLU132 |
| A | ILE133 |
| A | LEU136 |
| A | PHE202 |
| A | 1E8514 |
| A | HOH631 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 511 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 512 |
| Chain | Residue |
| A | THR123 |
| A | LEU187 |
| A | CYS198 |
| A | PHE199 |
| A | GLY200 |
| A | HOH609 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 513 |
| Chain | Residue |
| A | GLU141 |
| A | VAL150 |
| A | TRP151 |
| A | LYS416 |
| site_id | AD5 |
| Number of Residues | 12 |
| Details | binding site for residue 1E8 A 514 |
| Chain | Residue |
| A | TYR121 |
| A | LEU122 |
| A | ILE133 |
| A | ASN138 |
| A | TRP151 |
| A | MET153 |
| A | GLY200 |
| A | THR201 |
| A | PHE209 |
| A | GLN227 |
| A | DMS510 |
| A | HOH645 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ViHrDVKpsNILL |
| Chain | Residue | Details |
| A | VAL255-LEU267 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP259 | |
| Chain | Residue | Details |
| A | LYS165 | |
| A | MET142 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by MAP3K => ECO:0000250 |
| Chain | Residue | Details |
| A | SER287 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by MAP3K => ECO:0000250 |
| Chain | Residue | Details |
| A | THR291 | |
