Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue PZK A 301 |
| Chain | Residue |
| A | ALA12 |
| A | ARG91 |
| A | ARG92 |
| A | LEU93 |
| A | MET95 |
| A | ALA212 |
| A | HOH540 |
| A | SER13 |
| A | GLY14 |
| A | ARG17 |
| A | GLU18 |
| A | LEU19 |
| A | LEU27 |
| A | PHE29 |
| A | HIS69 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | ARG103 |
| A | GLY108 |
| A | SER109 |
| A | ARG222 |
| A | EDO304 |
| A | HOH450 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | PRO218 |
| A | SER221 |
| A | TYR223 |
| A | SER237 |
| A | ASP239 |
| A | LYS240 |
| A | HOH443 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ASP196 |
| A | SER220 |
| A | ARG222 |
| A | SO4302 |
| A | HOH427 |
| A | HOH476 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ASP156 |
| A | HOH556 |
| A | HOH590 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | HIS228 |
| A | VAL234 |
| A | GLN235 |
| A | ASP236 |
| A | HOH461 |
| A | HOH492 |
Functional Information from PROSITE/UniProt
| site_id | PS01057 |
| Number of Residues | 15 |
| Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. MLPVEcVARgylTGS |
| Chain | Residue | Details |
| A | MET95-SER109 | |
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. LADtKFEFG |
| Chain | Residue | Details |
| A | LEU194-GLY202 | |
