Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6YWE

The structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003735	molecular_function	structural constituent of ribosome
0	0005739	cellular_component	mitochondrion
0	0005840	cellular_component	ribosome
0	0006412	biological_process	translation
0	1990904	cellular_component	ribonucleoprotein complex
00	0005739	cellular_component	mitochondrion
00	0032780	biological_process	negative regulation of ATP-dependent activity
00	0042030	molecular_function	ATPase inhibitor activity
11	0003735	molecular_function	structural constituent of ribosome
11	0032543	biological_process	mitochondrial translation
2	0003735	molecular_function	structural constituent of ribosome
2	0032543	biological_process	mitochondrial translation
22	0005739	cellular_component	mitochondrion
3	0003735	molecular_function	structural constituent of ribosome
3	0005762	cellular_component	mitochondrial large ribosomal subunit
4	0003735	molecular_function	structural constituent of ribosome
4	0032543	biological_process	mitochondrial translation
44	0004784	molecular_function	superoxide dismutase activity
44	0006801	biological_process	superoxide metabolic process
44	0046872	molecular_function	metal ion binding
5	0003725	molecular_function	double-stranded RNA binding
5	0004525	molecular_function	ribonuclease III activity
5	0006396	biological_process	RNA processing
55	0004784	molecular_function	superoxide dismutase activity
55	0006801	biological_process	superoxide metabolic process
55	0046872	molecular_function	metal ion binding
6	0003735	molecular_function	structural constituent of ribosome
66	0003735	molecular_function	structural constituent of ribosome
66	0005739	cellular_component	mitochondrion
66	0005763	cellular_component	mitochondrial small ribosomal subunit
66	0032543	biological_process	mitochondrial translation
7	0003735	molecular_function	structural constituent of ribosome
7	0005739	cellular_component	mitochondrion
7	0005762	cellular_component	mitochondrial large ribosomal subunit
7	0005840	cellular_component	ribosome
7	0006412	biological_process	translation
7	1990904	cellular_component	ribonucleoprotein complex
8	0005739	cellular_component	mitochondrion
8	0005840	cellular_component	ribosome
8	1990904	cellular_component	ribonucleoprotein complex
88	0003824	molecular_function	catalytic activity
88	0003860	molecular_function	3-hydroxyisobutyryl-CoA hydrolase activity
88	0005739	cellular_component	mitochondrion
88	0006574	biological_process	L-valine catabolic process
88	0016787	molecular_function	hydrolase activity
9	0003735	molecular_function	structural constituent of ribosome
9	0004525	molecular_function	ribonuclease III activity
9	0005762	cellular_component	mitochondrial large ribosomal subunit
9	0006396	biological_process	RNA processing
9	0032543	biological_process	mitochondrial translation
99	0005739	cellular_component	mitochondrion
99	0032780	biological_process	negative regulation of ATP-dependent activity
99	0042030	molecular_function	ATPase inhibitor activity
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0015934	cellular_component	large ribosomal subunit
B	0016740	molecular_function	transferase activity
BB	0003735	molecular_function	structural constituent of ribosome
BB	0005739	cellular_component	mitochondrion
BB	0005763	cellular_component	mitochondrial small ribosomal subunit
BB	0005840	cellular_component	ribosome
BB	0006412	biological_process	translation
BB	0015935	cellular_component	small ribosomal subunit
BB	1990904	cellular_component	ribonucleoprotein complex
C	0003735	molecular_function	structural constituent of ribosome
C	0005762	cellular_component	mitochondrial large ribosomal subunit
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	1990904	cellular_component	ribonucleoprotein complex
CC	0005840	cellular_component	ribosome
D	0003735	molecular_function	structural constituent of ribosome
D	0005739	cellular_component	mitochondrion
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	1990904	cellular_component	ribonucleoprotein complex
DD	0003723	molecular_function	RNA binding
DD	0019843	molecular_function	rRNA binding
E	0000166	molecular_function	nucleotide binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	1990904	cellular_component	ribonucleoprotein complex
EE	0003723	molecular_function	RNA binding
EE	0003735	molecular_function	structural constituent of ribosome
EE	0005739	cellular_component	mitochondrion
EE	0005763	cellular_component	mitochondrial small ribosomal subunit
EE	0005840	cellular_component	ribosome
EE	0006412	biological_process	translation
EE	1990904	cellular_component	ribonucleoprotein complex
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
FF	0003735	molecular_function	structural constituent of ribosome
FF	0005840	cellular_component	ribosome
FF	0006412	biological_process	translation
FF	0019843	molecular_function	rRNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
GG	0006412	biological_process	translation
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
HH	0003735	molecular_function	structural constituent of ribosome
HH	0005840	cellular_component	ribosome
HH	0006412	biological_process	translation
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0015934	cellular_component	large ribosomal subunit
II	0003735	molecular_function	structural constituent of ribosome
II	0005840	cellular_component	ribosome
II	0006412	biological_process	translation
J	0003735	molecular_function	structural constituent of ribosome
J	0006412	biological_process	translation
J	0015934	cellular_component	large ribosomal subunit
JJ	0003735	molecular_function	structural constituent of ribosome
JJ	0005840	cellular_component	ribosome
JJ	0006412	biological_process	translation
K	0003735	molecular_function	structural constituent of ribosome
K	0005762	cellular_component	mitochondrial large ribosomal subunit
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
K	0032543	biological_process	mitochondrial translation
K	0046872	molecular_function	metal ion binding
K	1990904	cellular_component	ribonucleoprotein complex
KK	0003735	molecular_function	structural constituent of ribosome
KK	0005840	cellular_component	ribosome
KK	0006412	biological_process	translation
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
LL	0003735	molecular_function	structural constituent of ribosome
LL	0005840	cellular_component	ribosome
LL	0006412	biological_process	translation
LL	0015935	cellular_component	small ribosomal subunit
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
MM	0003676	molecular_function	nucleic acid binding
MM	0003723	molecular_function	RNA binding
MM	0003735	molecular_function	structural constituent of ribosome
MM	0005739	cellular_component	mitochondrion
MM	0005763	cellular_component	mitochondrial small ribosomal subunit
MM	0005777	cellular_component	peroxisome
MM	0005840	cellular_component	ribosome
MM	0006412	biological_process	translation
MM	0015935	cellular_component	small ribosomal subunit
MM	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005762	cellular_component	mitochondrial large ribosomal subunit
N	0005840	cellular_component	ribosome
NN	0003735	molecular_function	structural constituent of ribosome
NN	0005840	cellular_component	ribosome
NN	0006412	biological_process	translation
O	0003735	molecular_function	structural constituent of ribosome
O	0005739	cellular_component	mitochondrion
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015934	cellular_component	large ribosomal subunit
O	1990904	cellular_component	ribonucleoprotein complex
OO	0003735	molecular_function	structural constituent of ribosome
OO	0005737	cellular_component	cytoplasm
OO	0005840	cellular_component	ribosome
OO	0006412	biological_process	translation
OO	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
PP	0003735	molecular_function	structural constituent of ribosome
PP	0005840	cellular_component	ribosome
PP	0006412	biological_process	translation
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
QQ	0003735	molecular_function	structural constituent of ribosome
QQ	0005840	cellular_component	ribosome
QQ	0006412	biological_process	translation
R	0003735	molecular_function	structural constituent of ribosome
R	0005739	cellular_component	mitochondrion
R	0005762	cellular_component	mitochondrial large ribosomal subunit
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	1990904	cellular_component	ribonucleoprotein complex
RR	0003735	molecular_function	structural constituent of ribosome
RR	0005763	cellular_component	mitochondrial small ribosomal subunit
RR	0005840	cellular_component	ribosome
RR	0006412	biological_process	translation
RR	0032543	biological_process	mitochondrial translation
RR	0070181	molecular_function	small ribosomal subunit rRNA binding
RR	1990904	cellular_component	ribonucleoprotein complex
S	0003735	molecular_function	structural constituent of ribosome
SS	0003723	molecular_function	RNA binding
SS	0003735	molecular_function	structural constituent of ribosome
SS	0005840	cellular_component	ribosome
SS	0006412	biological_process	translation
T	0003735	molecular_function	structural constituent of ribosome
T	0005761	cellular_component	mitochondrial ribosome
T	0006412	biological_process	translation
TT	0003735	molecular_function	structural constituent of ribosome
TT	0005840	cellular_component	ribosome
TT	0006412	biological_process	translation
U	0003735	molecular_function	structural constituent of ribosome
U	0005739	cellular_component	mitochondrion
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015934	cellular_component	large ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
UU	0003735	molecular_function	structural constituent of ribosome
UU	0005763	cellular_component	mitochondrial small ribosomal subunit
V	0003735	molecular_function	structural constituent of ribosome
V	0005762	cellular_component	mitochondrial large ribosomal subunit
V	0005840	cellular_component	ribosome
V	0032543	biological_process	mitochondrial translation
VV	0003735	molecular_function	structural constituent of ribosome
VV	0005739	cellular_component	mitochondrion
W	0003735	molecular_function	structural constituent of ribosome
W	0005739	cellular_component	mitochondrion
W	0005762	cellular_component	mitochondrial large ribosomal subunit
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0015934	cellular_component	large ribosomal subunit
W	0046872	molecular_function	metal ion binding
W	1990904	cellular_component	ribonucleoprotein complex
WW	0005739	cellular_component	mitochondrion
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
XX	0003735	molecular_function	structural constituent of ribosome
XX	0005739	cellular_component	mitochondrion
XX	0005763	cellular_component	mitochondrial small ribosomal subunit
XX	0005840	cellular_component	ribosome
XX	0032543	biological_process	mitochondrial translation
XX	1990904	cellular_component	ribonucleoprotein complex
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	1990904	cellular_component	ribonucleoprotein complex
ZZ	0003735	molecular_function	structural constituent of ribosome
ZZ	0005739	cellular_component	mitochondrion
ZZ	0005763	cellular_component	mitochondrial small ribosomal subunit
ZZ	0005840	cellular_component	ribosome
ZZ	0032543	biological_process	mitochondrial translation
ZZ	1990904	cellular_component	ribonucleoprotein complex
a	0003735	molecular_function	structural constituent of ribosome
a	0005762	cellular_component	mitochondrial large ribosomal subunit
a	0005840	cellular_component	ribosome
b	0003735	molecular_function	structural constituent of ribosome
b	0005762	cellular_component	mitochondrial large ribosomal subunit
d	0000150	molecular_function	DNA strand exchange activity
d	0003697	molecular_function	single-stranded DNA binding
d	0006310	biological_process	DNA recombination
d	0032543	biological_process	mitochondrial translation
e	0003735	molecular_function	structural constituent of ribosome
e	0005762	cellular_component	mitochondrial large ribosomal subunit
e	0005840	cellular_component	ribosome
e	1990904	cellular_component	ribonucleoprotein complex
f	0005840	cellular_component	ribosome
g	0003735	molecular_function	structural constituent of ribosome
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
h	0003735	molecular_function	structural constituent of ribosome
h	0005739	cellular_component	mitochondrion
h	0005762	cellular_component	mitochondrial large ribosomal subunit
h	0005840	cellular_component	ribosome
h	1990904	cellular_component	ribonucleoprotein complex
j	0003735	molecular_function	structural constituent of ribosome
j	0005739	cellular_component	mitochondrion
j	0005840	cellular_component	ribosome
j	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkqkvqrr.DGsvvrFddNacVL

Chain	Residue	Details
I	ALA69-LEU95

site_id	PS00166
Number of Residues	21
Details	ENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. VAfLDGitmGGGvglsIhAPF

Chain	Residue	Details
88	VAL163-PHE183

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKdyidltVteemVGhkLGEFsaT

Chain	Residue	Details
SS	ASN57-THR81

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGttGQaeAitlAiAKAL

Chain	Residue	Details
II	GLY254-LEU272

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGI

Chain	Residue	Details
F	PRO232-ILE240

site_id	PS00626
Number of Residues	11
Details	RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. FTSGtQHGLTL

Chain	Residue	Details
AA	PHE98-LEU108

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLdiaIFRalfAsSarqARqMV

Chain	Residue	Details
DD	LEU140-VAL164

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLaaLgLrRrnQtVfhpvepqfagMLmkVkeLV

Chain	Residue	Details
U	VAL22-VAL54

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGrRHamGlpVRGQ

Chain	Residue	Details
MM	ARG87-GLN100

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGkGKGsfdhW

Chain	Residue	Details
K	ARG149-TRP160

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. LkLRLARFGR

Chain	Residue	Details
PP	LEU3-ARG12

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. LeDLMAAQAHMG

Chain	Residue	Details
BB	LEU160-GLY171

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IhTTypKaKeaqrlaEkLITlSK

Chain	Residue	Details
L	ILE35-LYS57

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P25348","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33056988","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	13
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)