Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | binding site for residue OMP A 501 |
Chain | Residue |
A | SER257 |
A | ASN341 |
A | MET371 |
A | SER372 |
A | PRO417 |
A | GLN430 |
A | TYR432 |
A | GLY450 |
A | ARG451 |
A | U502 |
A | HOH631 |
A | ASP259 |
A | HOH634 |
A | HOH676 |
A | HOH759 |
A | LYS281 |
A | HIS283 |
A | ASP312 |
A | ALY314 |
A | ASP317 |
A | ILE318 |
A | THR321 |
site_id | AC2 |
Number of Residues | 20 |
Details | binding site for residue U A 502 |
Chain | Residue |
A | SER257 |
A | ASP259 |
A | LYS281 |
A | HIS283 |
A | ASP312 |
A | ALY314 |
A | ASP317 |
A | ILE318 |
A | THR321 |
A | MET371 |
A | SER372 |
A | PRO417 |
A | GLN430 |
A | TYR432 |
A | GLY450 |
A | ARG451 |
A | OMP501 |
A | HOH631 |
A | HOH634 |
A | HOH676 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue GOL A 503 |
Chain | Residue |
A | ARG235 |
A | LYS468 |
A | HOH611 |
A | HOH912 |
A | HOH921 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 504 |
Chain | Residue |
A | THR374 |
A | GLY429 |
A | HOH620 |
A | HOH633 |
A | HOH640 |
site_id | AC5 |
Number of Residues | 1 |
Details | binding site for residue SO4 A 505 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 506 |
Chain | Residue |
A | ASN433 |
A | ARG442 |
A | HOH604 |
site_id | AC7 |
Number of Residues | 2 |
Details | binding site for residue SO4 A 507 |
Chain | Residue |
A | GLY380 |
A | ARG384 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 508 |
Chain | Residue |
A | SER348 |
A | LYS352 |
A | HIS393 |
A | HOH632 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 509 |
Chain | Residue |
A | ARG388 |
A | HOH644 |
A | HOH665 |
A | HOH735 |
Functional Information from PROSITE/UniProt
site_id | PS00156 |
Number of Residues | 14 |
Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IFeDrKfaDIGnTV |
Chain | Residue | Details |
A | ILE309-VAL322 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | PRO435 | |
Chain | Residue | Details |
A | GLU437 | |
Chain | Residue | Details |
A | ARG459 | |
Chain | Residue | Details |
A | GLU392 | |