6YSP
Arabidopsis aspartate transcarbamoylase complex with PALA and carbamoyl phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| C | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue CP A 401 |
| Chain | Residue |
| A | SER134 |
| A | HOH644 |
| C | SER163 |
| C | HOH510 |
| A | THR135 |
| A | ARG136 |
| A | THR137 |
| A | ARG187 |
| A | HIS215 |
| A | GLN218 |
| A | PRO349 |
| A | LEU350 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG310 |
| A | GLN312 |
| A | ARG313 |
| A | HOH512 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | ILE111 |
| A | GLU112 |
| A | SER114 |
| A | SER116 |
| A | GLN117 |
| A | SER118 |
| A | ARG147 |
| A | HOH505 |
| C | GLY123 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue CP B 401 |
| Chain | Residue |
| A | SER163 |
| A | LYS166 |
| B | SER134 |
| B | THR135 |
| B | ARG136 |
| B | THR137 |
| B | ARG187 |
| B | HIS215 |
| B | GLN218 |
| B | PRO349 |
| B | LEU350 |
| B | GOL404 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | ARG248 |
| B | THR249 |
| B | GLN312 |
| B | ARG315 |
| B | GOL404 |
| B | HOH603 |
| B | HOH632 |
| B | HOH670 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | ARG95 |
| B | SER99 |
| B | GLN227 |
| B | LYS232 |
| B | LEU233 |
| B | ASP234 |
| B | HOH507 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| A | LYS166 |
| A | HOH622 |
| A | HOH685 |
| B | HIS215 |
| B | LEU350 |
| B | PRO351 |
| B | CP401 |
| B | SO4402 |
| B | HOH511 |
| B | HOH528 |
| B | HOH603 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| A | GLY123 |
| B | ILE111 |
| B | SER114 |
| B | SER116 |
| B | GLN117 |
| B | SER118 |
| B | ARG147 |
| B | HOH675 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue PAL C 401 |
| Chain | Residue |
| B | SER163 |
| B | LYS166 |
| C | SER134 |
| C | THR135 |
| C | ARG136 |
| C | THR137 |
| C | ARG187 |
| C | HIS215 |
| C | GLN218 |
| C | ARG248 |
| C | THR249 |
| C | ARG310 |
| C | GLN312 |
| C | LEU350 |
| C | PRO351 |
| C | HOH586 |
| C | HOH587 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| B | GLY123 |
| B | LYS342 |
| C | ILE111 |
| C | SER114 |
| C | SER116 |
| C | GLN117 |
| C | SER118 |
| C | ARG147 |
| C | HOH522 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | ILE331 |
| C | HOH504 |
| C | HOH566 |
| C | HOH634 |
| C | LYS329 |
| C | PHE330 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FyEpSTRT |
| Chain | Residue | Details |
| A | PHE130-THR137 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33574254 |
| Chain | Residue | Details |
| A | ARG136 | |
| B | HIS215 | |
| B | ARG248 | |
| B | ARG310 | |
| C | ARG136 | |
| C | THR137 | |
| C | ARG187 | |
| C | HIS215 | |
| C | ARG248 | |
| C | ARG310 | |
| A | THR137 | |
| A | ARG187 | |
| A | HIS215 | |
| A | ARG248 | |
| A | ARG310 | |
| B | ARG136 | |
| B | THR137 | |
| B | ARG187 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P0A786 |
| Chain | Residue | Details |
| A | LYS166 | |
| C | GLN218 | |
| C | LEU350 | |
| C | PRO351 | |
| A | GLN218 | |
| A | LEU350 | |
| A | PRO351 | |
| B | LYS166 | |
| B | GLN218 | |
| B | LEU350 | |
| B | PRO351 | |
| C | LYS166 |
