6YS3
Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| 0 | 0003735 | molecular_function | structural constituent of ribosome |
| 0 | 0005840 | cellular_component | ribosome |
| 0 | 0006412 | biological_process | translation |
| 1 | 0003735 | molecular_function | structural constituent of ribosome |
| 1 | 0005840 | cellular_component | ribosome |
| 1 | 0006412 | biological_process | translation |
| 2 | 0003735 | molecular_function | structural constituent of ribosome |
| 2 | 0006412 | biological_process | translation |
| 2 | 0015934 | cellular_component | large ribosomal subunit |
| 3 | 0003735 | molecular_function | structural constituent of ribosome |
| 3 | 0006412 | biological_process | translation |
| 3 | 0015934 | cellular_component | large ribosomal subunit |
| 4 | 0003735 | molecular_function | structural constituent of ribosome |
| 4 | 0005840 | cellular_component | ribosome |
| 4 | 0006412 | biological_process | translation |
| 6 | 0003735 | molecular_function | structural constituent of ribosome |
| 6 | 0005840 | cellular_component | ribosome |
| 6 | 0006412 | biological_process | translation |
| 7 | 0003735 | molecular_function | structural constituent of ribosome |
| 7 | 0005840 | cellular_component | ribosome |
| 7 | 0006412 | biological_process | translation |
| 8 | 0003735 | molecular_function | structural constituent of ribosome |
| 8 | 0005840 | cellular_component | ribosome |
| 8 | 0006412 | biological_process | translation |
| c | 0003723 | molecular_function | RNA binding |
| c | 0003735 | molecular_function | structural constituent of ribosome |
| c | 0005840 | cellular_component | ribosome |
| c | 0006412 | biological_process | translation |
| c | 0015934 | cellular_component | large ribosomal subunit |
| c | 0016740 | molecular_function | transferase activity |
| d | 0003735 | molecular_function | structural constituent of ribosome |
| d | 0005840 | cellular_component | ribosome |
| d | 0006412 | biological_process | translation |
| e | 0003735 | molecular_function | structural constituent of ribosome |
| e | 0005840 | cellular_component | ribosome |
| e | 0006412 | biological_process | translation |
| f | 0003735 | molecular_function | structural constituent of ribosome |
| f | 0005840 | cellular_component | ribosome |
| f | 0006412 | biological_process | translation |
| g | 0003735 | molecular_function | structural constituent of ribosome |
| g | 0005840 | cellular_component | ribosome |
| g | 0006412 | biological_process | translation |
| g | 0019843 | molecular_function | rRNA binding |
| h | 0003735 | molecular_function | structural constituent of ribosome |
| h | 0005840 | cellular_component | ribosome |
| h | 0006412 | biological_process | translation |
| j | 0003735 | molecular_function | structural constituent of ribosome |
| j | 0005840 | cellular_component | ribosome |
| j | 0006412 | biological_process | translation |
| k | 0003735 | molecular_function | structural constituent of ribosome |
| k | 0005840 | cellular_component | ribosome |
| k | 0006412 | biological_process | translation |
| k | 0015934 | cellular_component | large ribosomal subunit |
| l | 0003735 | molecular_function | structural constituent of ribosome |
| l | 0005840 | cellular_component | ribosome |
| l | 0006412 | biological_process | translation |
| l | 0015934 | cellular_component | large ribosomal subunit |
| m | 0003735 | molecular_function | structural constituent of ribosome |
| m | 0005840 | cellular_component | ribosome |
| m | 0006412 | biological_process | translation |
| m | 0019843 | molecular_function | rRNA binding |
| n | 0003735 | molecular_function | structural constituent of ribosome |
| n | 0005840 | cellular_component | ribosome |
| n | 0006412 | biological_process | translation |
| o | 0003735 | molecular_function | structural constituent of ribosome |
| o | 0005840 | cellular_component | ribosome |
| o | 0006412 | biological_process | translation |
| p | 0003735 | molecular_function | structural constituent of ribosome |
| p | 0005840 | cellular_component | ribosome |
| p | 0006412 | biological_process | translation |
| q | 0003735 | molecular_function | structural constituent of ribosome |
| q | 0005840 | cellular_component | ribosome |
| q | 0006412 | biological_process | translation |
| q | 0019843 | molecular_function | rRNA binding |
| r | 0003723 | molecular_function | RNA binding |
| r | 0003735 | molecular_function | structural constituent of ribosome |
| r | 0005840 | cellular_component | ribosome |
| r | 0006412 | biological_process | translation |
| s | 0003735 | molecular_function | structural constituent of ribosome |
| s | 0005840 | cellular_component | ribosome |
| s | 0006412 | biological_process | translation |
| s | 0015934 | cellular_component | large ribosomal subunit |
| t | 0003735 | molecular_function | structural constituent of ribosome |
| t | 0005840 | cellular_component | ribosome |
| t | 0006412 | biological_process | translation |
| t | 0019843 | molecular_function | rRNA binding |
| u | 0003723 | molecular_function | RNA binding |
| u | 0003735 | molecular_function | structural constituent of ribosome |
| u | 0005840 | cellular_component | ribosome |
| u | 0006412 | biological_process | translation |
| w | 0003735 | molecular_function | structural constituent of ribosome |
| w | 0005840 | cellular_component | ribosome |
| w | 0006412 | biological_process | translation |
| w | 0008097 | molecular_function | 5S rRNA binding |
| y | 0003735 | molecular_function | structural constituent of ribosome |
| y | 0005840 | cellular_component | ribosome |
| y | 0006412 | biological_process | translation |
Functional Information from PROSITE/UniProt
| site_id | PS00049 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkgvrrp.DGsvirFdgNacVL |
| Chain | Residue | Details |
| k | ALA60-LEU86 |
| site_id | PS00050 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVTLKegqnldfV |
| Chain | Residue | Details |
| t | LYS81-VAL96 |
| site_id | PS00358 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L5 Ribosomal protein L5 signature. LaaISGQkpLiTkARkS |
| Chain | Residue | Details |
| f | LEU57-SER73 |
| site_id | PS00430 |
| Number of Residues | 66 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK |
| Chain | Residue | Details |
| t | MET1-LYS66 |
| site_id | PS00464 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV |
| Chain | Residue | Details |
| s | LYS83-VAL107 |
| site_id | PS00467 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGTAmNPvD |
| Chain | Residue | Details |
| c | PRO218-ASP229 |
| site_id | PS00474 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FadvkkvDvtGtSkGKGfaGtvkR |
| Chain | Residue | Details |
| d | PHE101-ARG124 |
| site_id | PS00475 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_L15 Ribosomal protein L15 signature. KVILaGeVttp..VtVrglrVTkgAraaIeaaG |
| Chain | Residue | Details |
| l | LYS109-GLY139 |
| site_id | PS00525 |
| Number of Residues | 9 |
| Details | RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGV |
| Chain | Residue | Details |
| g | PRO154-VAL162 |
| site_id | PS00579 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV |
| Chain | Residue | Details |
| 1 | GLN39-VAL53 |
| site_id | PS00582 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L33 Ribosomal protein L33 signature. YtTtKNkrtkPekLElkKFD |
| Chain | Residue | Details |
| 4 | TYR21-ASP40 |
| site_id | PS00586 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRqGKIWIRVFP |
| Chain | Residue | Details |
| m | LYS58-PRO69 |
| site_id | PS00634 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_L30 Ribosomal protein L30 signature. TLlgLgLrRigHtVeredtpairgMInaVsfMV |
| Chain | Residue | Details |
| 2 | THR23-VAL55 |
| site_id | PS00651 |
| Number of Residues | 28 |
| Details | RIBOSOMAL_L9 Ribosomal protein L9 signature. GslGdqvnVkaGYarNFLvpqgkAvpaT |
| Chain | Residue | Details |
| h | GLY13-THR40 |
| site_id | PS00701 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGkGKGnveyW |
| Chain | Residue | Details |
| m | ARG81-TRP92 |
| site_id | PS00783 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRamfrkLkVYaG |
| Chain | Residue | Details |
| j | VAL105-GLY127 |
| site_id | PS00784 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR |
| Chain | Residue | Details |
| 6 | LYS2-ARG21 |
| site_id | PS00828 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L36 Ribosomal protein L36 signature. CrnCkiVkRdgvIrViCsaepKHkQrQ |
| Chain | Residue | Details |
| 8 | CYS11-GLN37 |
| site_id | PS00831 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L27 Ribosomal protein L27 signature. GsIIvRQRGtkfhaG |
| Chain | Residue | Details |
| y | GLY34-GLY48 |
| site_id | PS00936 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L35 Ribosomal protein L35 signature. KTVrGAaKRFkktgkggfkhkhanl.RH |
| Chain | Residue | Details |
| 7 | LYS5-HIS31 |
| site_id | PS00937 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRqLWIARINaaaR |
| Chain | Residue | Details |
| q | LYS54-ARG70 |
| site_id | PS01015 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGAVR.KAKLYYLR |
| Chain | Residue | Details |
| p | VAL86-ARG101 |
| site_id | PS01108 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV |
| Chain | Residue | Details |
| u | ASP8-VAL25 |
| site_id | PS01167 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTlpKaKelrrvvEpLITlAK |
| Chain | Residue | Details |
| n | ILE34-LYS56 |
| site_id | PS01169 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L21 Ribosomal protein L21 signature. VkivKfrrRKhyrkqqGHRQwfT |
| Chain | Residue | Details |
| r | VAL72-THR94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:34403461, ECO:0000269|PubMed:34504068, ECO:0000312|PDB:7O19, ECO:0000312|PDB:7O1A, ECO:0000312|PDB:7O1C, ECO:0000312|PDB:7OIZ, ECO:0000312|PDB:7OJ0 |
| Chain | Residue | Details |
| s | LYS90 | |
| h | LYS83 | |
| h | LYS112 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: (3R)-3-hydroxyarginine => ECO:0000269|PubMed:23103944 |
| Chain | Residue | Details |
| m | ARG81 |
